Претраживање
Приказ резултата 1-10 од 123
Evidence of recombination in Tula virus strains from Serbia
(Elsevier, Amsterdam, 2014)
Tula hantavirus (TULV) belongs to Bunyaviridae family, with negative sense RNA genome. Segmented nature of hantaviral genome allows for genetic reassortment, but the evidence of homologous recombination also exists. In ...
Chronic alpha(1)-adrenoreceptor blockade produces age-dependent changes in rat thymus structure and thymocyte differentiation
(F Hernandez, Murcia, 2005)
In order to examine the influence of chronic alpha(1)-adrenergic receptor (alpha(1)-AR) blockade on the thymus structure and T-cell maturation, peripubertal and adult male rats were treated with urapidil (0.20 mg/kg BW/d; ...
Gonadal hormone dependent developmental plasticity of catecholamine:beta 2-adrenoceptor signaling complex in male rat thymus: Putative implications for thymopoiesis
(Elsevier, Amsterdam, 2013)
The study was undertaken considering that: i) androgens affect beta(2)-adrenoceptor (AR)-mediated catecholamine (CA) action in many tissues; and ii) peripubertal changes in both circulating androgen and thymic CA levels ...
Long-term beta-adrenergic receptor blockade increases levels of the most mature thymocyte subsets in aged rats
(Elsevier, Amsterdam, 2007)
Age-related increase in the density of thymic noradrenergic fibres and noradrenaline (NA) concentration is proposed to be associated with thymic involution and altered thymopoiesis. To test this hypothesis thymocyte ...
Murine Monoclonal Antibody 26 Raised Against Tetanus Toxoid Cross-Reacts with beta(2)-Glycoprotein I: Its Characteristics and Role in Molecular Mimicry
(Wiley, Hoboken, 2009)
Studies on experimental antiphospholipid syndrome (APS) models proved that molecular mimicry between plasma protein beta(2)-glycoprotein I (beta(2)GPI) and structure within micro-organisms or their products, might be a ...
Differential effects of chronic propranolol treatment on the phenotypic profile of thymocytes from immature and adult rats
(Elsevier, Amsterdam, 2000)
To elucidate a putative role of beta-adrenoceptors in the modulation of intrathymic T-cell maturation, the expression of major differentiational antigene (CD4/CD8 and TCR alpha beta) on the thymocytes from both immature ...
Sex-Based Differences in Monocytic Lineage Cells Contribute to More Severe Collagen-Induced Arthritis in Female Rats Compared with Male Rats
(Springer/Plenum Publishers, New York, 2020)
Monocytes' plasticity has an important role in the development of rheumatoid arthritis (RA), an autoimmune disease exhibiting greater prevalence in women. Contribution of this phenomenon to sex bias in RA severity was ...
Role of ovarian hormones in T-cell homeostasis: From the thymus to the periphery
(Elsevier Gmbh, Urban & Fischer Verlag, Jena, 2013)
The study explored the putative role of ovarian hormones in the peripubertal remodelling of peripheral T-cell compartment. Ovariectomy at age of 1 month enhanced the peripubertal rise in CD4+ and CD8+ cell numbers in ...
Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4+T cells in aged rats
(BMC, London, 2015)
Background: Aging influences immune response and susceptibility to EAE in a strain specific manner. The study was designed to examine influence of aging on EAE induction in Albino Oxford (AO) rats. Results: Differently ...
Somatostatin modulates T cells development in adult rat thymus
(Elsevier Science Bv, Amsterdam, 2007)
It is well known that somatostatin modulates thymic functions, such as binding to receptors. In order to elucidate the influence of somatostatin on the thymus architecture and the T cells maturation, young adult male rats ...