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Neonatal castration affects intrathymic kinetics of T-cell differentiation and the spleen T-cell level
(Bioscientifica Ltd, Bristol, 2007)
To test putative interdependence in the ontogenesis of the hypothalamic-pituitary-gonadal and thymic-lymphatic axes, thymocyte differentiation and maturation was examined in neonatally castrated (Cx) adult rats. In the ...
Long-term beta-adrenergic receptor blockade increases levels of the most mature thymocyte subsets in aged rats
(Elsevier, Amsterdam, 2007)
Age-related increase in the density of thymic noradrenergic fibres and noradrenaline (NA) concentration is proposed to be associated with thymic involution and altered thymopoiesis. To test this hypothesis thymocyte ...
Murine Monoclonal Antibody 26 Raised Against Tetanus Toxoid Cross-Reacts with beta(2)-Glycoprotein I: Its Characteristics and Role in Molecular Mimicry
(Wiley, Hoboken, 2009)
Studies on experimental antiphospholipid syndrome (APS) models proved that molecular mimicry between plasma protein beta(2)-glycoprotein I (beta(2)GPI) and structure within micro-organisms or their products, might be a ...
Differential effects of chronic propranolol treatment on the phenotypic profile of thymocytes from immature and adult rats
(Elsevier, Amsterdam, 2000)
To elucidate a putative role of beta-adrenoceptors in the modulation of intrathymic T-cell maturation, the expression of major differentiational antigene (CD4/CD8 and TCR alpha beta) on the thymocytes from both immature ...
Changes in thymus size, cellularity and relation between thymocyte subpopulations in young adult rats induced by Somatostatin-14
(Churchill Livingstone, Edinburgh, 2007)
The role of somatostatin on inhibition of both normal and tumor cell cycle, secretion of endocrine and exocrine cells, as well as induction apoptosis is well documented. However, its effect on T cell development and thymic ...
Maturation of IgG avidity to individual rubella virus structural proteins
(Elsevier, Amsterdam, 2001)
Background: the structural proteins of rubella virus, the capsid protein C and the envelope glycoproteins E1 and E2 were produced in lepidopteran insect cells using baculovirus expression vectors. The C-terminal ends of ...
Beta-endorphin differentially affects inflammation in two inbred rat strains
(Elsevier, Amsterdam, 2006)
It has been shown that inflammation of rat paws elicits accumulation of opioid peptide is-endorphin-containing immune cells in the inflamed subcutaneous tissue, contributing to immumocyte-produced pain suppression. However, ...
The influence of stress and methionine-enkephalin on macrophage functions in two inbred rat strains
(Pergamon-Elsevier Science Ltd, Oxford, 2007)
The aim of our current study was to investigate the effect of acute exposure to electric tail shock stress (ES) and to a stress witnessing procedure (SW), as models for physical and psychological stress paradigms, respectively, ...
Methionine-enkephalin stimulates hydrogen peroxide and nitric oxide production in rat peritoneal macrophages: Interaction of mu, delta and kappa opioid receptors
(Karger, Basel, 2004)
Objective: Methionine-enkephalin ( MET) modulates various functions of macrophages related to both immune and inflammatory reactions in a naloxone reversible manner, suggesting that opioid receptors are involved in the ...
Reactive oxygen species (ROS), but not nitric oxide (NO), contribute to strain differences in the susceptibility to experimental arthritis in rats
(Elsevier Gmbh, Munich, 2007)
There is extensive evidence for the critical role of reactive oxygen species (ROS) and nitric oxide (NO) produced by phagocytes in development of inflammatory processes and pathogenesis of numerous diseases, including ...