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Long-term beta-adrenergic receptor blockade increases levels of the most mature thymocyte subsets in aged rats
(Elsevier, Amsterdam, 2007)
Age-related increase in the density of thymic noradrenergic fibres and noradrenaline (NA) concentration is proposed to be associated with thymic involution and altered thymopoiesis. To test this hypothesis thymocyte ...
Murine Monoclonal Antibody 26 Raised Against Tetanus Toxoid Cross-Reacts with beta(2)-Glycoprotein I: Its Characteristics and Role in Molecular Mimicry
(Wiley, Hoboken, 2009)
Studies on experimental antiphospholipid syndrome (APS) models proved that molecular mimicry between plasma protein beta(2)-glycoprotein I (beta(2)GPI) and structure within micro-organisms or their products, might be a ...
Differential effects of chronic propranolol treatment on the phenotypic profile of thymocytes from immature and adult rats
(Elsevier, Amsterdam, 2000)
To elucidate a putative role of beta-adrenoceptors in the modulation of intrathymic T-cell maturation, the expression of major differentiational antigene (CD4/CD8 and TCR alpha beta) on the thymocytes from both immature ...
Changes in pools of autoantibodies and anti-bacterial antibodies in patients suffering from recurrent infections of the urinary tract and undergoing bacterial immunization treatment
(Elsevier, Amsterdam, 2004)
Antibodies (Abs) (IgM, IgA IgG and IgG subclasses) specific for several uropathogenic strains (Escherichia coli, Pseudomonas sp. and Klebsiella sp.) as well as anti-phospholipids, anti-beta(2)-glycoprotein I and anti-laminin ...
Early postnatal castration affects thymic and thymocyte noradrenaline levels and beta-adrenoceptor-mediated influence on the thymopoiesis in adult rats
(Elsevier, Amsterdam, 2007)
The interactions among the nervous, endocrine and immune system were studied by examining: i) thymic and thymocyte catecholamine levels in adult rats castrated (Cx) at postnatal day 3 and ii) effects of 14-day-long propranolol ...
Beta-adrenoceptor blockade ameliorates the clinical course of experimental allergic encephalomyelitis and diminishes its aggravation in adrenalectomized rats
(Elsevier Science Bv, Amsterdam, 2007)
As glucocorticoids influence both catecholamine synthesis and adrenoceptor expression by immune cells, the current study was undertaken to distinguish their direct effects on the development of experimental allergic ...
Peripubertal orchidectomy transitorily affects age-associated thymic involution in rats
(Assoc Bras Divulg Cientifica, Sao Paulo, 2007)
The role of gonadal hormones in induction and, particularly, maintenance/ progression of rat thymic involution, which normally starts around puberty, was reassessed by examining the effects of peripubertal orchidectomy on ...
Somatostatin modulates T cells development in adult rat thymus
(Elsevier Science Bv, Amsterdam, 2007)
It is well known that somatostatin modulates thymic functions, such as binding to receptors. In order to elucidate the influence of somatostatin on the thymus architecture and the T cells maturation, young adult male rats ...
Changes in thymus size, cellularity and relation between thymocyte subpopulations in young adult rats induced by Somatostatin-14
(Churchill Livingstone, Edinburgh, 2007)
The role of somatostatin on inhibition of both normal and tumor cell cycle, secretion of endocrine and exocrine cells, as well as induction apoptosis is well documented. However, its effect on T cell development and thymic ...
Morphometrical characteristics of age-associated changes in the thymus of old male wistar rats
(Wiley, Hoboken, 2006)
In order to provide a morphometrical description of the changes in the aged rat thymus and to relate them to apoptotic and proliferative activity of thymocytes, the thymuses from 3- and 18-month-old male Wistar rats and ...