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Peripheral effects of methionine-enkephalin on inflammatory reactions and behavior in the rat
(Karger, Basel, 2000)
Methionine-enkephalin (Met-Enk) induces notable alterations in immune and central nervous system functions. The present study was conducted in order to compare peripheral and central effects of Met-Enk on nonspecific ...
The influence of stress and methionine-enkephalin on macrophage functions in two inbred rat strains
(Pergamon-Elsevier Science Ltd, Oxford, 2007)
The aim of our current study was to investigate the effect of acute exposure to electric tail shock stress (ES) and to a stress witnessing procedure (SW), as models for physical and psychological stress paradigms, respectively, ...
Methionine-enkephalin stimulates hydrogen peroxide and nitric oxide production in rat peritoneal macrophages: Interaction of mu, delta and kappa opioid receptors
(Karger, Basel, 2004)
Objective: Methionine-enkephalin ( MET) modulates various functions of macrophages related to both immune and inflammatory reactions in a naloxone reversible manner, suggesting that opioid receptors are involved in the ...
Modulation of humoral immune responses in the rat by centrally applied Met-Enk and opioid receptor antagonists: functional interactions of brain OP1, OP2 and OP3 receptors
(Elsevier, Amsterdam, 2000)
We have previously demonstrated that central application of leucine-enkephalin (Leu-Enk) elicits potentiation and suppression of humoral immune responses through OP1 (delta) and OP2 (kappa) receptors, respectively. ...
Different effects of methionine-enkephalin on paw edema in two inbred rat strains
(Elsevier Science Inc, New York, 2002)
The effect of intraplantarly (i.pl.)-injected methionine-enkephalin (ME) on Concanavalin A (Con A)-induced paw edema in Dark Agouti (DA) and Albino Oxford (AO) rats was investigated. ME suppressed edema in DA rats, which ...
The effect of opioid peptides on superoxide, anion production in rat peritoneal macrophages stimulated with zymosan: involvement of µ, δ and κ opioid receptors / Uticaj opioidnih peptida na produkciju superoksid anjona u peritonealnim makrofagama pacova stimulisanim zimozanom - uloga µ, δ i κ opioidnih receptora
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2002)
It is well documented that endogenous opioid peptides modulate the activity of immune and inflammatory cells. Opioid peptides exert biological effects through at least three opioid receptor types, known as µ, δ and κ. In ...