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Peripheral effects of methionine-enkephalin on inflammatory reactions and behavior in the rat
(Karger, Basel, 2000)
Methionine-enkephalin (Met-Enk) induces notable alterations in immune and central nervous system functions. The present study was conducted in order to compare peripheral and central effects of Met-Enk on nonspecific ...
Modulation of humoral immune responses in the rat by centrally applied Met-Enk and opioid receptor antagonists: functional interactions of brain OP1, OP2 and OP3 receptors
(Elsevier, Amsterdam, 2000)
We have previously demonstrated that central application of leucine-enkephalin (Leu-Enk) elicits potentiation and suppression of humoral immune responses through OP1 (delta) and OP2 (kappa) receptors, respectively. ...