The neuronal and immune memory systems as supervisors of neural plasticity and aging of the brain - From phenomenology to coding of information
Samo za registrovane korisnike
2005
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The ultimate goal of this report is to learn how to manipulate the level of memory T cells for more effective treatment of such neurological diseases as multiple sclerosis (MS), where certain T cell subsets recognize self-antigens as opposed to pathogen antigens, and Alzheimer's disease (AD). Brain lesions (electrolitically, by kainic acid, with AlCl, and with 6-OHDA); stimulations (electrical, magnetic, or pharmacological); or restoration of some neurological functions (thermoregulatory and behavioral) by fetal graft allotransplantations in bilaterally lesioned anterior hypothalamic area (AHA-immune regulation) and nucleus basalis magnocellularis (NBM-experimental AD) in our studies were designed to reproduce immune and cognitive deficits induced by lesions of these brain structures. To localize memory traces in the immune system and in the brain we used ethanol and drugs such as kainic acid and 6-OHDA, which have been used very effectively to produce temporary lesions in the brain. R...ats showed no learning and memory ability as well as inhibition of immune reactions.
Ključne reči:
rats / brain lesions / brain stimulation / fetal allotransplantation / behavior / experimental allergic encephalomyelitis / Alzheimer's diseaseIzvor:
Reversal of Aging: Resetting the Pineal Clock, 2005, 1057, 279-295Izdavač:
- New York Acad Sciences, New York
DOI: 10.1196/annals.1356.022
ISSN: 0077-8923
PubMed: 16399901
WoS: 000236116800018
Scopus: 2-s2.0-32244434515
Institucija/grupa
TorlakTY - JOUR AU - Jovanova-Nešić, Katica AU - Janković, B.D. PY - 2005 UR - http://intor.torlakinstitut.com/handle/123456789/202 AB - The ultimate goal of this report is to learn how to manipulate the level of memory T cells for more effective treatment of such neurological diseases as multiple sclerosis (MS), where certain T cell subsets recognize self-antigens as opposed to pathogen antigens, and Alzheimer's disease (AD). Brain lesions (electrolitically, by kainic acid, with AlCl, and with 6-OHDA); stimulations (electrical, magnetic, or pharmacological); or restoration of some neurological functions (thermoregulatory and behavioral) by fetal graft allotransplantations in bilaterally lesioned anterior hypothalamic area (AHA-immune regulation) and nucleus basalis magnocellularis (NBM-experimental AD) in our studies were designed to reproduce immune and cognitive deficits induced by lesions of these brain structures. To localize memory traces in the immune system and in the brain we used ethanol and drugs such as kainic acid and 6-OHDA, which have been used very effectively to produce temporary lesions in the brain. Rats showed no learning and memory ability as well as inhibition of immune reactions. PB - New York Acad Sciences, New York T2 - Reversal of Aging: Resetting the Pineal Clock T1 - The neuronal and immune memory systems as supervisors of neural plasticity and aging of the brain - From phenomenology to coding of information EP - 295 SP - 279 VL - 1057 DO - 10.1196/annals.1356.022 ER -
@article{ author = "Jovanova-Nešić, Katica and Janković, B.D.", year = "2005", abstract = "The ultimate goal of this report is to learn how to manipulate the level of memory T cells for more effective treatment of such neurological diseases as multiple sclerosis (MS), where certain T cell subsets recognize self-antigens as opposed to pathogen antigens, and Alzheimer's disease (AD). Brain lesions (electrolitically, by kainic acid, with AlCl, and with 6-OHDA); stimulations (electrical, magnetic, or pharmacological); or restoration of some neurological functions (thermoregulatory and behavioral) by fetal graft allotransplantations in bilaterally lesioned anterior hypothalamic area (AHA-immune regulation) and nucleus basalis magnocellularis (NBM-experimental AD) in our studies were designed to reproduce immune and cognitive deficits induced by lesions of these brain structures. To localize memory traces in the immune system and in the brain we used ethanol and drugs such as kainic acid and 6-OHDA, which have been used very effectively to produce temporary lesions in the brain. Rats showed no learning and memory ability as well as inhibition of immune reactions.", publisher = "New York Acad Sciences, New York", journal = "Reversal of Aging: Resetting the Pineal Clock", title = "The neuronal and immune memory systems as supervisors of neural plasticity and aging of the brain - From phenomenology to coding of information", pages = "295-279", volume = "1057", doi = "10.1196/annals.1356.022" }
Jovanova-Nešić, K.,& Janković, B.D.. (2005). The neuronal and immune memory systems as supervisors of neural plasticity and aging of the brain - From phenomenology to coding of information. in Reversal of Aging: Resetting the Pineal Clock New York Acad Sciences, New York., 1057, 279-295. https://doi.org/10.1196/annals.1356.022
Jovanova-Nešić K, Janković B. The neuronal and immune memory systems as supervisors of neural plasticity and aging of the brain - From phenomenology to coding of information. in Reversal of Aging: Resetting the Pineal Clock. 2005;1057:279-295. doi:10.1196/annals.1356.022 .
Jovanova-Nešić, Katica, Janković, B.D., "The neuronal and immune memory systems as supervisors of neural plasticity and aging of the brain - From phenomenology to coding of information" in Reversal of Aging: Resetting the Pineal Clock, 1057 (2005):279-295, https://doi.org/10.1196/annals.1356.022 . .