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Importance of immunological and inflammatory processes in the pathogenesis and therapy of Alzheimer's disease
(Taylor & Francis Ltd, Abingdon, 1998)
The contribution of autoimmune processes or inflammatory components in the etiology and pathogenesis of Alzheimer's disease (AD) has been suspected for many years. The presence of antigen-presenting, HLA-DR-positive and ...
Cold restraint-induced gastric lesions in individual- and group-stressed rats
(Taylor & Francis Ltd, Abingdon, 1997)
The aim of the present study was to 1) determine the intensity of cold restraint-induced gastric lesions and core body temperature in single-and group-stressed rats, and establish a correlation between them; and 2) determine ...
Cold restraint-induced gastric lesions in individual-and group-stressed rats in an experimental model of Alzheimer's disease
(Taylor & Francis Ltd, Abingdon, 1998)
Ten days after bilateral electrolytic lesions of the nucleus basalis magnocellularis (NBM) (an experimental model of Alzheimer's disease), adult male Wistar rats were exposed to cold restraint stress in individual and ...
Neuroprotective effect of chronic verapamil treatment on cognitive and noncognitive deficits in an experimental Alzheimer's disease in rats
(Taylor & Francis Ltd, Abingdon, 1997)
It is well known that disturbance of calcium homeostasis has a significant role in the development of neurodegenerative disorders, such as Alzheimer's disease (AD). Our recent data suggest that acute treatment with the ...
Humoral and cell-mediated immune responses following lesions of the nucleus basalis magnocellularis in the rat
(Taylor & Francis Ltd, Abingdon, 1997)
The present study was undertaken to elucidate whether electrolytic lesions of nucleus basalis magnocellularis-NBM (an animal model of Alzheimer's disease-AD) may influence humoral and cellular immune responses in adult ...
Effect of physostigmine and verapamil on active avoidance in an experimental model of Alzheimer's disease
(Taylor & Francis Ltd, Abingdon, 1997)
The present study was performed to investigate and compare the effect of acetylcholinesterase inhibitor, physostigmine (0.045, 0.060 and 0.075 mg/kg sc, 30 min before the tests) and Ca-antagonist, verapamil (1.0, 2.5, 5.0 ...
Open field behavior in nucleus basalis magnocellularis-lesioned rats treated with physostigmine and verapamil
(Taylor & Francis Ltd, Abingdon, 1997)
The present study was done to investigate and compare the effect of acetylcholinesterase inhibitor, physostigmine (0.030, 0.045, 0.060 and 0.075 mg/kg sc) and Ca-antagonist, verapamil (1.0, 2.5, 5.0 and 10.0 mg/kg sc) on ...
Orchidectomy affects the innervation of the rat thymus
(Taylor & Francis Ltd, Abingdon, 1999)
To assess a putative role of the neural pathways in transfer of information from the gonads to the thymus, adult AO rats were orchidectomized (ORX) or sham ORX (controls); sacrificed 1, 3, 7, or 15 days later and their ...
Behavioral and adaptive status in an experimental model of Alzheimer's disease in rats
(Taylor & Francis Ltd, Abingdon, 1996)
Ten days after bilateral electrolytic lesions of nucleus basalis magnocellularis (NBM) we tested behavioral (spontaneous motor activity, acquisition and performance of two-way active avoidance, fear-response in open field ...
Learning and memory in nucleus basalis magnocellularis-lesioned rats after transplantation of fetal frontal cortex
(Taylor & Francis Ltd, Abingdon, 1997)
The effect of fetal frontal cortex transplantation on behaviour performance was examined in adult male Wistar rats with lesions of the nucleus basalis magnocellularis (NBM). Compared to intact and sham-operated controls, ...