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Correlation between age-related changes in open field behavior and plaque forming cell response in DA female rats
(Taylor & Francis Ltd, Abingdon, 2003)
We investigated the relationship between immunological and behavioral changes during ageing in Dark Agouti female rats. Results showed that ageing was associated with decreased exploratory behavior and increased emotionality ...
Polymorphisms of the Prion Protein Gene (PRNP) in a Serbian Population
(Taylor & Francis Ltd, Abingdon, 2010)
Prion diseases are a group of etiologically heterogenous neurodegenerative disorders. We have analyzed the coding region of PRNP gene in 121 healthy citizens of Serbia to determine whether the frequencies of M129V, E219K, ...
Schizophrenia and Apolipoprotein E Gene Polymorphism in Serbian Population
(Taylor & Francis Ltd, Abingdon, 2010)
Apolipoprotein E (APOE) gene variants are associated with alterations in brain function and increased risk of Alzheimer's disease (AD) and conflicting results have been reported in schizophrenia. Our results showed no ...
Orchidectomy affects the innervation of the rat thymus
(Taylor & Francis Ltd, Abingdon, 1999)
To assess a putative role of the neural pathways in transfer of information from the gonads to the thymus, adult AO rats were orchidectomized (ORX) or sham ORX (controls); sacrificed 1, 3, 7, or 15 days later and their ...
Behavioral and adaptive status in an experimental model of Alzheimer's disease in rats
(Taylor & Francis Ltd, Abingdon, 1996)
Ten days after bilateral electrolytic lesions of nucleus basalis magnocellularis (NBM) we tested behavioral (spontaneous motor activity, acquisition and performance of two-way active avoidance, fear-response in open field ...
Importance of immunological and inflammatory processes in the pathogenesis and therapy of Alzheimer's disease
(Taylor & Francis Ltd, Abingdon, 1998)
The contribution of autoimmune processes or inflammatory components in the etiology and pathogenesis of Alzheimer's disease (AD) has been suspected for many years. The presence of antigen-presenting, HLA-DR-positive and ...
Cold restraint-induced gastric lesions in individual- and group-stressed rats
(Taylor & Francis Ltd, Abingdon, 1997)
The aim of the present study was to 1) determine the intensity of cold restraint-induced gastric lesions and core body temperature in single-and group-stressed rats, and establish a correlation between them; and 2) determine ...
Humoral and cell-mediated immune responses following lesions of the nucleus basalis magnocellularis in the rat
(Taylor & Francis Ltd, Abingdon, 1997)
The present study was undertaken to elucidate whether electrolytic lesions of nucleus basalis magnocellularis-NBM (an animal model of Alzheimer's disease-AD) may influence humoral and cellular immune responses in adult ...
Open field behavior in nucleus basalis magnocellularis-lesioned rats treated with physostigmine and verapamil
(Taylor & Francis Ltd, Abingdon, 1997)
The present study was done to investigate and compare the effect of acetylcholinesterase inhibitor, physostigmine (0.030, 0.045, 0.060 and 0.075 mg/kg sc) and Ca-antagonist, verapamil (1.0, 2.5, 5.0 and 10.0 mg/kg sc) on ...
Effects of beta-adrenoceptor blockade on the phenotypic characteristics of thymocytes and peripheral blood lymphocytes
(Taylor & Francis Ltd, Abingdon, 2003)
The study revealed that beta-adrenoceptor blockade with propranolol (0.40 mg/100 g/day, s.c.) in adult male DA rats: (i) increased the thymocyte proliferation and apoptosis, (ii) caused disturbances in kinetics of T cell ...