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Sex Difference in Oxidative Stress Parameters in Spinal Cord of Rats with Experimental Autoimmune Encephalomyelitis: Relation to Neurological Deficit
(Springer/Plenum Publishers, New York, 2017)
The study examined (a) whether there is sex difference in spinal cord and plasma oxidative stress profiles in Dark Agouti rats immunised for experimental autoimmune encephalomyelitis (EAE), the principal experimental model ...
Strain specificities in influence of ageing on germinal centre reaction to inactivated influenza virus antigens in mice: Sex-based differences
(Pergamon-Elsevier Science Ltd, Oxford, 2020)
Considering variability in vaccine responsiveness across human populations, in respect to magnitude and quality, and importance of vaccines in the elderly, the influence of recipient genetic background on the kinetics of ...
Age and sex determine CD4+T cell stimulatory and polarizing capacity of rat splenic dendritic cells
(Springer, New York, 2020)
The study investigated influence of sex and age on splenic myeloid dendritic cells (DCs) from Dark Agouti rats. Freshly isolated DCs from young males exhibited less mature phenotype and greater endocytic capacity compared ...
Influence of aging on germinal centre reaction and antibody response to inactivated influenza virus antigens in mice: sex-based differences
(Springer, New York, 2019)
The study examined sex-specificities in age-related changes in BALB/c mice IgG antibody responses to immunisation with trivalent inactivated split-virus influenza bulk. Aging diminished the total serum IgG antibody responses ...
Sexual diergism in antibody response to whole virus trivalent inactivated influenza vaccine in outbred mice
(Elsevier Sci Ltd, Oxford, 2015)
An outbred mouse model was used to determine if antibody response to immunization with whole-virus trivalent inactivated influenza vaccine (TIV) differs between the sexes. The antibody response was examined one (serum titer ...
Mouse strain and sex as determinants of immune response to trivalent influenza vaccine
(Pergamon-Elsevier Science Ltd, Oxford, 2018)
Aims: The study examined the influence of sex and mouse strain on germinal center (GC) reaction and antibody responses to seasonal split trivalent influenza vaccine (TIV). Main methods: C57BL/6 and BALB/c mice of both sexes ...
Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammation
(Springer, New York, 2019)
The study investigated mechanisms underlying sex differences in thymic involution in Dark Agouti rats. Adverse effects of aging on thymus were more pronounced in males than in females. Thymi from old males exhibited more ...
Sex as a confounding factor in the effects of ageing on rat lymph node t cell compartment
(Pergamon-Elsevier Science Ltd, Oxford, 2020)
The study examined the influence of sex on the alterations occurring with ageing in rat lymph node (LN) T cell compartment. In female and male rats the decrease in LN T cell counts was followed by a shift in CD4+/CD8+ T ...
Sexual dimorphism in Th17/Treg axis in lymph nodes draining inflamed joints in rats with collagen-induced arthritis
(Academic Press Inc Elsevier Science, San Diego, 2019)
Collagen type II-induced arthritis (CIA) in Dark Agouti rats, a model of rheumatoid arthritis (RA), reproduces sexual dimorphism in the incidence and severity of the human disease. Th17 cells are central in the ...
Sex bias in mouse humoral immune response to influenza vaccine depends on the vaccine type
(Academic Press Ltd- Elsevier Science Ltd, London, 2018)
The study explored influence of biological sex on development of humoral immune response to seasonal trivalent whole inactivated virus (WIV) and split virus (SV) influenza vaccines in outbred Swiss mouse model. To this ...