TY  - JOUR
AU  - Dimitrijević, Mirjana
AU  - Stanojević, Stanislava
AU  - Vujić, Vesna
AU  - Kovačević-Jovanović, Vesna
AU  - Beck-Sickinger, A.
AU  - Demuth, H.U.
AU  - von Hoersten, Stephan
PY  - 2002
UR  - http://intor.torlakinstitut.com/handle/123456789/153
AB  - Several lines of evidence suggest that neuropeptide Y (NPY) may exert regulatory effects in local inflammatory responses. Here, we show that intraplantarly (i.pl.) applied NPY, peptide YY (PYY), and an NPY Y5 receptor-selective agonist dose-dependently potentiate concanavalin A (Con A)-induced paw edema in the rat. The NPY Y1 receptor antagonist BIBO 3304 abolishes the pro-inflammatory action of both NPY and PYY while the dipeptidyl-peptidase IV (CD26) inhibitor Ile-thiazolidide exerted synergistic and potentiating effects in vivo. Taken together, the present data reveal an NPY Y1/Y5 receptor interplay and an involvement of CD26 in the NPY-induced potentiation of paw edema in the rat. (C) 2002 Elsevier Science B.V. All rights reserved.
PB  - Elsevier, Amsterdam
T2  - Journal of Neuroimmunology
T1  - Effect of neuropeptide Y on inflammatory paw edema in the rat: involvement of peripheral NPYY1 and Y5 receptors and interaction with dipeptidyl-peptidase IV (CD26)
EP  - 42
IS  - 1-2
SP  - 35
VL  - 129
DO  - 10.1016/S0165-5728(02)00173-X
ER  - 

@article{
author = "Dimitrijević, Mirjana and Stanojević, Stanislava and Vujić, Vesna and Kovačević-Jovanović, Vesna and Beck-Sickinger, A. and Demuth, H.U. and von Hoersten, Stephan",
year = "2002",
abstract = "Several lines of evidence suggest that neuropeptide Y (NPY) may exert regulatory effects in local inflammatory responses. Here, we show that intraplantarly (i.pl.) applied NPY, peptide YY (PYY), and an NPY Y5 receptor-selective agonist dose-dependently potentiate concanavalin A (Con A)-induced paw edema in the rat. The NPY Y1 receptor antagonist BIBO 3304 abolishes the pro-inflammatory action of both NPY and PYY while the dipeptidyl-peptidase IV (CD26) inhibitor Ile-thiazolidide exerted synergistic and potentiating effects in vivo. Taken together, the present data reveal an NPY Y1/Y5 receptor interplay and an involvement of CD26 in the NPY-induced potentiation of paw edema in the rat. (C) 2002 Elsevier Science B.V. All rights reserved.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Neuroimmunology",
title = "Effect of neuropeptide Y on inflammatory paw edema in the rat: involvement of peripheral NPYY1 and Y5 receptors and interaction with dipeptidyl-peptidase IV (CD26)",
pages = "42-35",
number = "1-2",
volume = "129",
doi = "10.1016/S0165-5728(02)00173-X"
}

Dimitrijević, M., Stanojević, S., Vujić, V., Kovačević-Jovanović, V., Beck-Sickinger, A., Demuth, H.U.,& von Hoersten, S.. (2002). Effect of neuropeptide Y on inflammatory paw edema in the rat: involvement of peripheral NPYY1 and Y5 receptors and interaction with dipeptidyl-peptidase IV (CD26). in Journal of Neuroimmunology
Elsevier, Amsterdam., 129(1-2), 35-42.
https://doi.org/10.1016/S0165-5728(02)00173-X

Dimitrijević M, Stanojević S, Vujić V, Kovačević-Jovanović V, Beck-Sickinger A, Demuth H, von Hoersten S. Effect of neuropeptide Y on inflammatory paw edema in the rat: involvement of peripheral NPYY1 and Y5 receptors and interaction with dipeptidyl-peptidase IV (CD26). in Journal of Neuroimmunology. 2002;129(1-2):35-42.
doi:10.1016/S0165-5728(02)00173-X .

Dimitrijević, Mirjana, Stanojević, Stanislava, Vujić, Vesna, Kovačević-Jovanović, Vesna, Beck-Sickinger, A., Demuth, H.U., von Hoersten, Stephan, "Effect of neuropeptide Y on inflammatory paw edema in the rat: involvement of peripheral NPYY1 and Y5 receptors and interaction with dipeptidyl-peptidase IV (CD26)" in Journal of Neuroimmunology, 129, no. 1-2 (2002):35-42,
https://doi.org/10.1016/S0165-5728(02)00173-X . .