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Noradrenaline modulates CD4+T cell priming in rat experimental autoimmune encephalomyelitis: a role for the alpha(1)-adrenoceptor
(Humana Press Inc, Totowa, 2019)
Pharmacological blockade of alpha(1)-adrenoceptor is shown to influence development of experimental autoimmune encephalomyelitis (EAE), an IL-17-producing CD4+TCR+ (Th17) cell-mediated disease mimicking multiple sclerosis. ...
Influence of aging on germinal centre reaction and antibody response to inactivated influenza virus antigens in mice: sex-based differences
(Springer, New York, 2019)
The study examined sex-specificities in age-related changes in BALB/c mice IgG antibody responses to immunisation with trivalent inactivated split-virus influenza bulk. Aging diminished the total serum IgG antibody responses ...
Noradrenaline through beta-adrenoceptor contributes to sexual dimorphism in primary CD4+T-cell response in DA rat EAE model?
(Academic Press Inc Elsevier Science, San Diego, 2019)
Males exhibit stronger sympathetic nervous system (SNS) activity, but weaker primary CD4 + T-cell (auto) immune responses. To test the role of catecholamines, major end-point SNS mediators, in this dimorphism, influence ...
Predictors of health related-quality of life among elderly with disabilities
(Wiley, Hoboken, 2019)
Aim There have been no previous studies of health-related quality of life (HRQOL) among adults aged 65 years and older with disabilities in Serbia. The aim of study was to identify predictors of HRQOL in the context of ...
Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammation
(Springer, New York, 2019)
The study investigated mechanisms underlying sex differences in thymic involution in Dark Agouti rats. Adverse effects of aging on thymus were more pronounced in males than in females. Thymi from old males exhibited more ...
Sexual dimorphism in Th17/Treg axis in lymph nodes draining inflamed joints in rats with collagen-induced arthritis
(Academic Press Inc Elsevier Science, San Diego, 2019)
Collagen type II-induced arthritis (CIA) in Dark Agouti rats, a model of rheumatoid arthritis (RA), reproduces sexual dimorphism in the incidence and severity of the human disease. Th17 cells are central in the ...
Propranolol Impairs Primary Immune Responses in Rat Experimental Autoimmune Encephalomyelitis
(Karger, Basel, 2019)
Objective: We examined the effect of beta-adrenoceptor (AR) blockade in the preclinical phase of experimental autoimmune encephalomyelitis (EAE), the most commonly used model of multiple sclerosis, on the development of ...
Health care quality challenges in low- and middle-income countries
(Oxford Univ Press, Oxford, 2019)
Sexual dimorphism in the severity of rat collagen-induced arthritis: the relevance of T follicular cell help to B cells
(Institute for Biological Research "Siniša Stanković" - National Institute of Republic of Serbia, University of BelgradeImmunological Society of Serbia, 2019)
Collagen-induced arthritis (CIA) is a well-established experimental model mimicking many immunopathogenic and clinical aspects of rheumatoid arthritis (RA), including sexual dimorphism in the clinical presentation. Our ...