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Changes in thymus size, cellularity and relation between thymocyte subpopulations in young adult rats induced by Somatostatin-14
(Churchill Livingstone, Edinburgh, 2007)
The role of somatostatin on inhibition of both normal and tumor cell cycle, secretion of endocrine and exocrine cells, as well as induction apoptosis is well documented. However, its effect on T cell development and thymic ...
Dysregulation of T-Cell Development in Adrenal Glucocorticoid-Deprived Rats
(Sage Publications Ltd, London, 2009)
A number of different experimental approaches have been used to elucidate the impact: of basal levels of adrenal gland-derived glucocorticoids (GCs) on T cell development, and thereby T cell-mediated immune responses. ...
Sexual dimorphism in the catecholamine-containing thymus microenvironment: A role for gonadal hormones
(Elsevier Science Bv, Amsterdam, 2008)
The study was undertaken to explore whether there were: i) apart from neural and circulatory, some other sources of catecholamines (CAs) in rat thymus and ii) gender-specific differences in thymic CA levels, and if so to ...
Neuropeptide Y receptor-specifically modulates human neutrophil function
(Elsevier Science Bv, Amsterdam, 2008)
Despite a continuously growing body of evidence highlighting the role of NPY in the immune system, surprisingly little is known about its ability to alter human leukocyte function. We therefore set out to examine NPY ...
The anti-inflammatory effect of neuropeptide Y (NPY) in rats is dependent on dipeptidyl peptidase 4 (DP4) activity and age
(Elsevier Science Inc, New York, 2008)
Neuropeptide Y (NPY)-induced modulation of the immune and inflammatory responses is regulated by tissue-specific expression of different receptor subtypes (Y1-Y6) and the activity of the enzyme dipeptidyl peptidase 4 (DP4, ...
Chronic propranolol treatment affects expression of adrenoceptors on peritoneal macrophages and their ability to produce hydrogen peroxide and nitric oxide
(Elsevier, Amsterdam, 2009)
Using both immunocytochemical and flow cytometric analyses of rat peritoneal exudate cells constitutive expression of tyrosine hydroxylase and both beta(2)- and alpha(1)-adrenoceptors on macrophages was revealed. Furthermore, ...
Methionine-enkephalin modulation of hydrogen peroxide (H2O2) release by rat peritoneal macrophages involves different types of opioid receptors
(Churchill Livingstone, Edinburgh, 2008)
We investigated the involvement of specific types of opioid receptors in methionine-enkephalin (MET)-induced modulation of hydrogen peroxide (H2O2) release by rat macrophages primed with sub-optimal concentrations of phorbol ...
Expression of alpha(1)-adrenoceptors on thymic cells and their role in fine tuning of thymopoiesis
(Elsevier Science Bv, Amsterdam, 2009)
The study was undertaken to explore: i) the presence of alpha(1)-adrenoceptors (AR) on thymic lymphoid and non-lymphoid cells and ii) their putative role in T-cell development. The expression of alpha(1)-AR on thymic cells ...
Somatostatin-14 alters relation between the thymocyte subpopulations in adult rats
(Elsevier, Amsterdam, 2004)