Neuropeptide Y receptor-specifically modulates human neutrophil function
Само за регистроване кориснике
2008
Аутори
Bedoui, SammyKromer, Andreas
Gebhardt, Thomas
Jacobs, Roland
Raber, Kerstin
Dimitrijević, Mirjana
Heine, Joern
von Hoersten, Stephan
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Despite a continuously growing body of evidence highlighting the role of NPY in the immune system, surprisingly little is known about its ability to alter human leukocyte function. We therefore set out to examine NPY receptor expression and functional effects of NPY in freshly isolated human neutrophils. Our results not only demonstrate for the first time the presence of specific NPY receptors on human neutrophils, but also unveil of how these receptors differentially modulate critical functions of neutrophils such as phagocytosis of bacteria as well as the release of reactive oxygen species. (C) 2008 Elsevier B.V. All rights reserved.
Кључне речи:
neuroimmune interactions / neuropeptide Y (NPY) / NPY receptors / human neutrophils / phagocytosis / reactive oxygen speciesИзвор:
Journal of Neuroimmunology, 2008, 195, 1-2, 88-95Издавач:
- Elsevier Science Bv, Amsterdam
DOI: 10.1016/j.jneuroim.2008.01.012
ISSN: 0165-5728
PubMed: 18343509
WoS: 000255802000010
Scopus: 2-s2.0-41949104683
Институција/група
TorlakTY - JOUR AU - Bedoui, Sammy AU - Kromer, Andreas AU - Gebhardt, Thomas AU - Jacobs, Roland AU - Raber, Kerstin AU - Dimitrijević, Mirjana AU - Heine, Joern AU - von Hoersten, Stephan PY - 2008 UR - http://intor.torlakinstitut.com/handle/123456789/252 AB - Despite a continuously growing body of evidence highlighting the role of NPY in the immune system, surprisingly little is known about its ability to alter human leukocyte function. We therefore set out to examine NPY receptor expression and functional effects of NPY in freshly isolated human neutrophils. Our results not only demonstrate for the first time the presence of specific NPY receptors on human neutrophils, but also unveil of how these receptors differentially modulate critical functions of neutrophils such as phagocytosis of bacteria as well as the release of reactive oxygen species. (C) 2008 Elsevier B.V. All rights reserved. PB - Elsevier Science Bv, Amsterdam T2 - Journal of Neuroimmunology T1 - Neuropeptide Y receptor-specifically modulates human neutrophil function EP - 95 IS - 1-2 SP - 88 VL - 195 DO - 10.1016/j.jneuroim.2008.01.012 ER -
@article{ author = "Bedoui, Sammy and Kromer, Andreas and Gebhardt, Thomas and Jacobs, Roland and Raber, Kerstin and Dimitrijević, Mirjana and Heine, Joern and von Hoersten, Stephan", year = "2008", abstract = "Despite a continuously growing body of evidence highlighting the role of NPY in the immune system, surprisingly little is known about its ability to alter human leukocyte function. We therefore set out to examine NPY receptor expression and functional effects of NPY in freshly isolated human neutrophils. Our results not only demonstrate for the first time the presence of specific NPY receptors on human neutrophils, but also unveil of how these receptors differentially modulate critical functions of neutrophils such as phagocytosis of bacteria as well as the release of reactive oxygen species. (C) 2008 Elsevier B.V. All rights reserved.", publisher = "Elsevier Science Bv, Amsterdam", journal = "Journal of Neuroimmunology", title = "Neuropeptide Y receptor-specifically modulates human neutrophil function", pages = "95-88", number = "1-2", volume = "195", doi = "10.1016/j.jneuroim.2008.01.012" }
Bedoui, S., Kromer, A., Gebhardt, T., Jacobs, R., Raber, K., Dimitrijević, M., Heine, J.,& von Hoersten, S.. (2008). Neuropeptide Y receptor-specifically modulates human neutrophil function. in Journal of Neuroimmunology Elsevier Science Bv, Amsterdam., 195(1-2), 88-95. https://doi.org/10.1016/j.jneuroim.2008.01.012
Bedoui S, Kromer A, Gebhardt T, Jacobs R, Raber K, Dimitrijević M, Heine J, von Hoersten S. Neuropeptide Y receptor-specifically modulates human neutrophil function. in Journal of Neuroimmunology. 2008;195(1-2):88-95. doi:10.1016/j.jneuroim.2008.01.012 .
Bedoui, Sammy, Kromer, Andreas, Gebhardt, Thomas, Jacobs, Roland, Raber, Kerstin, Dimitrijević, Mirjana, Heine, Joern, von Hoersten, Stephan, "Neuropeptide Y receptor-specifically modulates human neutrophil function" in Journal of Neuroimmunology, 195, no. 1-2 (2008):88-95, https://doi.org/10.1016/j.jneuroim.2008.01.012 . .