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Age-related changes in spleen of Dark Agouti rats immunized for experimental autoimmune encephalomyelitis
(Elsevier Science Bv, Amsterdam, 2015)
The study was undertaken considering age-related changes in susceptibility to experimental autoimmune encephalomyelitis (EAE) and a putative role of spleen in pathogenesis of this disease. The phenotypic and functional ...
Sex Bias in Pathogenesis of Autoimmune Neuroinflammation: Relevance for Dimethyl Fumarate Immunomodulatory/Anti-oxidant Action
(Springer, New York, 2018)
In the present study, upon showing sexual dimorphism in dimethyl fumarate (DMF) efficacy to moderate the clinical severity of experimental autoimmune encephalomyelitis (EAE) in Dark Agouti rats, cellular and molecular ...
NMDA Receptor Antagonist Memantine Ameliorates Experimental Autoimmune Encephalomyelitis in Aged Rats
(MDPI, 2024)
Aging is closely related to the main aspects of multiple sclerosis (MS). The average age of the MS population is increasing and the number of elderly MS patients is expected to increase. In addition to neurons, ...
Influenza vaccine and learning in C57BL mice with an acute experimental autoimmune encephalomyelitis
(Versita, Warsaw, 2014)
Literature data suggest possible link between influenza vaccination and development of autoimmune processes. Therefore, the aim of the study was to investigate the effect of influenza vaccination on spatial learning in ...
Levamisole modulates experimental autoimmune encephalomyelitis (EAE) in DA rats / Modulacija eksperimentalnog autoimunog encefalomijelitisa (EAE) DA pacova levamizolom
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2001)
We investigated the influence of an antiparasitic drug, levamisole (2,3,5,6 - tetrahydro - 6- phenyl-imidazo (2,1 - b) thiazole -hydrochloride) with potent immunomodulatory properties on the course and development of ...
Strain specificities in age-related changes in mechanisms promoting and controlling rat spinal cord damage in experimental autoimmune encephalomyelitis
(Pergamon-Elsevier Science Ltd, Oxford, 2018)
The study investigated strain specificities in age-related differences in CD8+ T cell-and microglial cell-mediated mechanisms implicated in induction/perpetuation and/or control of neuroinflammation in experimental autoimmune ...
Strain specificities in cellular and molecular immunopathogenic mechanisms underlying development of experimental autoimmune encephalomyelitis in aged rats
(Elsevier Ireland Ltd, Clare, 2017)
To understand strain-specificities of immune system in aged rats and their immunopathological implications, CD4+T lymphocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis (EAE) was studied in two ...
Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4+T cells in aged rats
(BMC, London, 2015)
Background: Aging influences immune response and susceptibility to EAE in a strain specific manner. The study was designed to examine influence of aging on EAE induction in Albino Oxford (AO) rats. Results: Differently ...
Pertussis vaccine-induced experimental autoimmune encephalomyelitis in mice
(De Gruyter Poland Sp Zoo, Warsaw, 2014)
A small dose of the Bordetella pertussis vaccine is used as an adjuvant for the induction of experimental autoimmune encephalomyelitis (EAE) in mice. The effects of two doses of the Pertussis vaccine on clinical signs, ...
Role of inactivated influenza vaccine in regulation of autoimmune processes in experimental autoimmune encephalomyelitis
(Taylor & Francis Ltd, Abingdon, 2014)
Experimental autoimmune encephalomyelitis (EAE) is characterized by appearance of anti-myelin autoantibodies in the blood and with the increased expression of MHC (major histocompatibility complex) class I and II antigens ...