Cytomegalovirus infection may be oncoprotective against neoplasms of B-lymphocyte lineage: single-institution experience and survey of global evidence
Authors
Janković, MarkoKnežević, Aleksandra
Todorović, Milena
Đunić, Irena
Mihaljević, Biljana
Soldatović, Ivan
Protić, Jelena
Miković, Nevenka
Stoiljković, Vera
Jovanović, Tanja
Article (Published version)
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Show full item recordAbstract
Although cytomegalovirus (CMV) is not considered tumorigenic, there is evidence for its oncomodulatory effects and association with hematological neoplasms. Conversely, a number of experimental and clinical studies suggest its putative anti-tumour effect. We investigated the potential connection between chronic CMV infection in patients with B-lymphocyte (B-cell) malignancies in a retrospective single-center study and extracted relevant data on CMV prevalences and the incidences of B-cell cancers the world over.
Keywords:
B-cell malignancies / Cytomegalovirus / Global / Oncoprotection / SeroprevalenceSource:
Virology Journal, 2022, 19, 1, 155-Publisher:
- BMC
Funding / projects:
- Rare Diseases:Molecular Pathophysiology, Diagnostic and Therapeutic Modalities and Social, Ethical and Legal Aspects (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41004)
- Importance of viral genetic variability in human diseases (RS-MESTD-Basic Research (BR or ON)-175073)
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TorlakTY - JOUR AU - Janković, Marko AU - Knežević, Aleksandra AU - Todorović, Milena AU - Đunić, Irena AU - Mihaljević, Biljana AU - Soldatović, Ivan AU - Protić, Jelena AU - Miković, Nevenka AU - Stoiljković, Vera AU - Jovanović, Tanja PY - 2022 UR - http://intor.torlakinstitut.com/handle/123456789/629 AB - Although cytomegalovirus (CMV) is not considered tumorigenic, there is evidence for its oncomodulatory effects and association with hematological neoplasms. Conversely, a number of experimental and clinical studies suggest its putative anti-tumour effect. We investigated the potential connection between chronic CMV infection in patients with B-lymphocyte (B-cell) malignancies in a retrospective single-center study and extracted relevant data on CMV prevalences and the incidences of B-cell cancers the world over. PB - BMC T2 - Virology Journal T1 - Cytomegalovirus infection may be oncoprotective against neoplasms of B-lymphocyte lineage: single-institution experience and survey of global evidence IS - 1 SP - 155 VL - 19 DO - 10.1186/s12985-022-01884-1 ER -
@article{ author = "Janković, Marko and Knežević, Aleksandra and Todorović, Milena and Đunić, Irena and Mihaljević, Biljana and Soldatović, Ivan and Protić, Jelena and Miković, Nevenka and Stoiljković, Vera and Jovanović, Tanja", year = "2022", abstract = "Although cytomegalovirus (CMV) is not considered tumorigenic, there is evidence for its oncomodulatory effects and association with hematological neoplasms. Conversely, a number of experimental and clinical studies suggest its putative anti-tumour effect. We investigated the potential connection between chronic CMV infection in patients with B-lymphocyte (B-cell) malignancies in a retrospective single-center study and extracted relevant data on CMV prevalences and the incidences of B-cell cancers the world over.", publisher = "BMC", journal = "Virology Journal", title = "Cytomegalovirus infection may be oncoprotective against neoplasms of B-lymphocyte lineage: single-institution experience and survey of global evidence", number = "1", pages = "155", volume = "19", doi = "10.1186/s12985-022-01884-1" }
Janković, M., Knežević, A., Todorović, M., Đunić, I., Mihaljević, B., Soldatović, I., Protić, J., Miković, N., Stoiljković, V.,& Jovanović, T.. (2022). Cytomegalovirus infection may be oncoprotective against neoplasms of B-lymphocyte lineage: single-institution experience and survey of global evidence. in Virology Journal BMC., 19(1), 155. https://doi.org/10.1186/s12985-022-01884-1
Janković M, Knežević A, Todorović M, Đunić I, Mihaljević B, Soldatović I, Protić J, Miković N, Stoiljković V, Jovanović T. Cytomegalovirus infection may be oncoprotective against neoplasms of B-lymphocyte lineage: single-institution experience and survey of global evidence. in Virology Journal. 2022;19(1):155. doi:10.1186/s12985-022-01884-1 .
Janković, Marko, Knežević, Aleksandra, Todorović, Milena, Đunić, Irena, Mihaljević, Biljana, Soldatović, Ivan, Protić, Jelena, Miković, Nevenka, Stoiljković, Vera, Jovanović, Tanja, "Cytomegalovirus infection may be oncoprotective against neoplasms of B-lymphocyte lineage: single-institution experience and survey of global evidence" in Virology Journal, 19, no. 1 (2022):155, https://doi.org/10.1186/s12985-022-01884-1 . .