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dc.creatorMirić, M.
dc.creatorBrkić, S.
dc.creatorKeserović, N.
dc.date.accessioned2021-02-18T10:18:33Z
dc.date.available2021-02-18T10:18:33Z
dc.date.issued1994
dc.identifier.issn0042-8450
dc.identifier.urihttp://intor.torlakinstitut.com/handle/123456789/56
dc.description.abstractThe therapeutic effects of human leucocytic interferon-α (IFN) on viral myocarditis and dilative cardiomyopathy (IDC) were investigated interferon-α in a dose of 3 million U/m body surface area daily for 4 weeks was administered i.m. to 7 patients, while 44 patients were treated with conventional therapy alone. During the 7-year follow-up period, initially depressed cardiac function normalized in patients treated with IFN, while it improved insignificantly in conventionally treated patients. Five patients on conventional therapy alone died during the follow-up period compared to one patient treated with interferon-α. No significant side effects attributable to interferon-α were observed during the study. According to several studies enterovirus genomes are found in about 25% of endomyocardial biopsies in patients with myocarditis and IDC, so that double-blind randomized trials to evaluate the therapeutic effects of IFN in this subgroup of patients are warranted.en
dc.publisherVojnomedicinska akademija - Institut za naučne informacije, Beograd
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-sa/4.0/
dc.sourceVojnosanitetski Pregled
dc.subjectCardiomyopathyen
dc.subjectCongestiveen
dc.subjectInterferon type Ien
dc.subjectMyocarditisen
dc.subjectVirus diseasesen
dc.titleInterferon-alpha: Elective therapy in viral myocarditis and idiopathic dilative cardiomyopathy?en
dc.typeconferenceObject
dc.rights.licenseBY-SA
dc.citation.epage97
dc.citation.issue4 SUPPL.
dc.citation.other51(4 SUPPL.): 93-97
dc.citation.spage93
dc.citation.volume51
dc.identifier.rcubconv_601
dc.identifier.scopus2-s2.0-0028564997
dc.type.versionpublishedVersion


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