Application of the 3r concept in the production of European antiviperinum on horses - multisite, low volumes immunization protocol and Elisa
Аутори
Milovanović, VladimirDimitrijević, Ljiljana
Petrušić, Vladimir
Kadrić, Jasminka
Minić, Rajna
Živković, Irena
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
During time, both professionals and general public became aware of the importance of animal welfare. This term not only covers endangered wild animal species, animals used in food industry, pets and experimental animals, but also animals used in production of biologics. The implementation of the 3R concept (Replacement, Reduction and Refinement) is especially important in this type of production. In this article, we describe for the first time the low dose, low volume and multi-site immunization protocol, as well as appropriate ELISA we developed for production of European anti-viper (V. ammodytes, long horned) antivenom in horses, which can help to significantly improve the welfare of the used animals.
Кључне речи:
adjuvant / animal welfare / antivenom production / European vipers / horses / immunization scheduleИзвор:
Acta veterinaria - Beograd, 2018, 68, 4, 401-419Издавач:
- Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
Финансирање / пројекти:
- Алергени, антитела, ензими и мали физиолошки значајни молекули: дизајн, структура, функција и значај (RS-MESTD-Basic Research (BR or ON)-172049)
DOI: 10.2478/acve-2018-0033
ISSN: 0567-8315
WoS: 000456859500003
Scopus: 2-s2.0-85060955289
Институција/група
TorlakTY - JOUR AU - Milovanović, Vladimir AU - Dimitrijević, Ljiljana AU - Petrušić, Vladimir AU - Kadrić, Jasminka AU - Minić, Rajna AU - Živković, Irena PY - 2018 UR - http://intor.torlakinstitut.com/handle/123456789/500 AB - During time, both professionals and general public became aware of the importance of animal welfare. This term not only covers endangered wild animal species, animals used in food industry, pets and experimental animals, but also animals used in production of biologics. The implementation of the 3R concept (Replacement, Reduction and Refinement) is especially important in this type of production. In this article, we describe for the first time the low dose, low volume and multi-site immunization protocol, as well as appropriate ELISA we developed for production of European anti-viper (V. ammodytes, long horned) antivenom in horses, which can help to significantly improve the welfare of the used animals. PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd T2 - Acta veterinaria - Beograd T1 - Application of the 3r concept in the production of European antiviperinum on horses - multisite, low volumes immunization protocol and Elisa EP - 419 IS - 4 SP - 401 VL - 68 DO - 10.2478/acve-2018-0033 ER -
@article{ author = "Milovanović, Vladimir and Dimitrijević, Ljiljana and Petrušić, Vladimir and Kadrić, Jasminka and Minić, Rajna and Živković, Irena", year = "2018", abstract = "During time, both professionals and general public became aware of the importance of animal welfare. This term not only covers endangered wild animal species, animals used in food industry, pets and experimental animals, but also animals used in production of biologics. The implementation of the 3R concept (Replacement, Reduction and Refinement) is especially important in this type of production. In this article, we describe for the first time the low dose, low volume and multi-site immunization protocol, as well as appropriate ELISA we developed for production of European anti-viper (V. ammodytes, long horned) antivenom in horses, which can help to significantly improve the welfare of the used animals.", publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd", journal = "Acta veterinaria - Beograd", title = "Application of the 3r concept in the production of European antiviperinum on horses - multisite, low volumes immunization protocol and Elisa", pages = "419-401", number = "4", volume = "68", doi = "10.2478/acve-2018-0033" }
Milovanović, V., Dimitrijević, L., Petrušić, V., Kadrić, J., Minić, R.,& Živković, I.. (2018). Application of the 3r concept in the production of European antiviperinum on horses - multisite, low volumes immunization protocol and Elisa. in Acta veterinaria - Beograd Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 68(4), 401-419. https://doi.org/10.2478/acve-2018-0033
Milovanović V, Dimitrijević L, Petrušić V, Kadrić J, Minić R, Živković I. Application of the 3r concept in the production of European antiviperinum on horses - multisite, low volumes immunization protocol and Elisa. in Acta veterinaria - Beograd. 2018;68(4):401-419. doi:10.2478/acve-2018-0033 .
Milovanović, Vladimir, Dimitrijević, Ljiljana, Petrušić, Vladimir, Kadrić, Jasminka, Minić, Rajna, Živković, Irena, "Application of the 3r concept in the production of European antiviperinum on horses - multisite, low volumes immunization protocol and Elisa" in Acta veterinaria - Beograd, 68, no. 4 (2018):401-419, https://doi.org/10.2478/acve-2018-0033 . .