Neuropeptide Y: The story, the players, the outcomes
Samo za registrovane korisnike
2012
Poglavlje u monografiji (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Neuropeptide Y (NPY) is a peptide consisted of 36 amino acids. It is designated by a capital letter Y due to the presence of many tyrosine residues which are abbreviated by the letter Y in the single letter amino acid code. NPY is one of the most evolutionary conserved peptides, originally isolated from pig brain (Tatemoto et al. 1982; Larhammar 1996). Due to a very wide tissue distribution of NPY and its significance for the human and animal physiology, peptides with high structural homology to NPY, e.g., peptide YY (PYY), pancreatic polypeptide (PP) and their truncated forms NPY2-36, NPY3-36 and PYY3-36, sharing amino acid backbone that forms a hair-pin turn called the PP-fold (Fuhlendorff et al. 1990), are now specified as members of NPY family. NPY was previously considered a companion and amplifier of norepinephrine activity. It is now known that NPY could be stored alone in small vesicles of sympathetic nerves, and in combination with catecholamines in large vesicles (Fried et al.... 1985). Although NPY is preferentially released under conditions of high frequency nerve stimulation, the endogenous NPY modulates the effects of norepinephrine at both high and low levels of sympathetic nerve activity (Han et al. 1998).
Ključne reči:
Experimental Autoimmune Encephalomyelitis / Cutaneous Leishmaniasis / Pancreatic Polypeptide / Single Letter Amino Acid Code / Receptor Specific AgonistIzvor:
Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System, 2012, 227-256Izdavač:
- Springer-Verlag Wien
Finansiranje / projekti:
- Plastičnost imunskog sistema tokom starenja: imunomodulatorni potencijal estrogena (RS-175050)
- Neuroendokrina modulacija imunskog odgovora: uloga simpato-adrenomedularnog sistema (RS-145049)
DOI: 10.1007/978-3-7091-0888-8_8
ISBN: Hardcover ISBN 978-3-7091-0887-1
Scopus: 2-s2.0-84883810683
Institucija/grupa
TorlakTY - CHAP AU - Dimitrijević, Mirjana AU - Stanojević, Stanislava PY - 2012 UR - http://intor.torlakinstitut.com/handle/123456789/352 AB - Neuropeptide Y (NPY) is a peptide consisted of 36 amino acids. It is designated by a capital letter Y due to the presence of many tyrosine residues which are abbreviated by the letter Y in the single letter amino acid code. NPY is one of the most evolutionary conserved peptides, originally isolated from pig brain (Tatemoto et al. 1982; Larhammar 1996). Due to a very wide tissue distribution of NPY and its significance for the human and animal physiology, peptides with high structural homology to NPY, e.g., peptide YY (PYY), pancreatic polypeptide (PP) and their truncated forms NPY2-36, NPY3-36 and PYY3-36, sharing amino acid backbone that forms a hair-pin turn called the PP-fold (Fuhlendorff et al. 1990), are now specified as members of NPY family. NPY was previously considered a companion and amplifier of norepinephrine activity. It is now known that NPY could be stored alone in small vesicles of sympathetic nerves, and in combination with catecholamines in large vesicles (Fried et al. 1985). Although NPY is preferentially released under conditions of high frequency nerve stimulation, the endogenous NPY modulates the effects of norepinephrine at both high and low levels of sympathetic nerve activity (Han et al. 1998). PB - Springer-Verlag Wien T2 - Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System T1 - Neuropeptide Y: The story, the players, the outcomes EP - 256 SP - 227 DO - 10.1007/978-3-7091-0888-8_8 ER -
@inbook{ author = "Dimitrijević, Mirjana and Stanojević, Stanislava", year = "2012", abstract = "Neuropeptide Y (NPY) is a peptide consisted of 36 amino acids. It is designated by a capital letter Y due to the presence of many tyrosine residues which are abbreviated by the letter Y in the single letter amino acid code. NPY is one of the most evolutionary conserved peptides, originally isolated from pig brain (Tatemoto et al. 1982; Larhammar 1996). Due to a very wide tissue distribution of NPY and its significance for the human and animal physiology, peptides with high structural homology to NPY, e.g., peptide YY (PYY), pancreatic polypeptide (PP) and their truncated forms NPY2-36, NPY3-36 and PYY3-36, sharing amino acid backbone that forms a hair-pin turn called the PP-fold (Fuhlendorff et al. 1990), are now specified as members of NPY family. NPY was previously considered a companion and amplifier of norepinephrine activity. It is now known that NPY could be stored alone in small vesicles of sympathetic nerves, and in combination with catecholamines in large vesicles (Fried et al. 1985). Although NPY is preferentially released under conditions of high frequency nerve stimulation, the endogenous NPY modulates the effects of norepinephrine at both high and low levels of sympathetic nerve activity (Han et al. 1998).", publisher = "Springer-Verlag Wien", journal = "Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System", booktitle = "Neuropeptide Y: The story, the players, the outcomes", pages = "256-227", doi = "10.1007/978-3-7091-0888-8_8" }
Dimitrijević, M.,& Stanojević, S.. (2012). Neuropeptide Y: The story, the players, the outcomes. in Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System Springer-Verlag Wien., 227-256. https://doi.org/10.1007/978-3-7091-0888-8_8
Dimitrijević M, Stanojević S. Neuropeptide Y: The story, the players, the outcomes. in Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System. 2012;:227-256. doi:10.1007/978-3-7091-0888-8_8 .
Dimitrijević, Mirjana, Stanojević, Stanislava, "Neuropeptide Y: The story, the players, the outcomes" in Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System (2012):227-256, https://doi.org/10.1007/978-3-7091-0888-8_8 . .