TY  - JOUR
AU  - Šuljagić, Vesna
AU  - Đurić-Petković, Danijela
AU  - Lazić, Srdan
AU  - Mladenović, Jovan
AU  - Rakonjac, Bojan
AU  - Opačić, Dolores
AU  - Ljubenović, Nenad
AU  - Milojković, Biljana
AU  - Radojević, Katarina
AU  - Nenezić, Ivana
AU  - Rančić, Nemanja
PY  - 2023
UR  - http://intor.torlakinstitut.com/handle/123456789/655
AB  - Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its resulting coronavirus disease 2019 (COVID-19) has caused a fast-moving pandemic. Diagnostic testing, aimed to identify patients infected with SARS-CoV-2, plays a key role in controlling the COVID-19 pandemic in different populations. (2) Methods: This retrospective cohort study aimed to investigate predictors associated with positive polymerase chain reaction (PCR) SARS-CoV-2 test results in hospitalized patients, healthcare workers (HCWs), and military personnel (MP) during 2020, before the widespread availability of COVID-19 vaccines. Persons with a positive test result were compared with persons with a negative test result in three cohorts during the study period. (3) Results: A total of 6912 respondents were tested, and 1334 (19.3%) of them had positive PCR SARS-CoV-2 test results. Contact with a known COVID-19 case within 14 days (p < 0.001; OR: 1.48; 95% CI: 1.25–1.76), fever (p < 0.001; OR: 3.66; 95% CI: 3.04–4.41), cough (p < 0.001; OR: 1.91; 95% CI: 1.59–2.30), headache (p = 0.028; OR: 1.24; 95% CI: 1.02–1.50), and myalgia/arthralgia (p < 0.001; OR: 1.99; 95% CI: 1.65–2.42) were independently associated with positive PCR SARS-CoV-2 test results in the cohort of MP. Furthermore, fever (p < 0.001; OR: 2.75; 95% CI: 1.83–4.13), cough (p < 0.001; OR: 2.04; 95% CI: 1.32–3.13), headache (p = 0.008; OR: 1.76; 95% CI: 1.15–2.68), and myalgia/arthralgia (p = 0.039; OR: 1.58; 95% CI: 1.02–2.45) were independently associated with positive PCR SARS-CoV-2 test results in the cohort of HCWs. Moreover, independent predictors of positive PCR SARS-CoV-2 test results in hospitalized patients were contact with a known COVID-19 case within 14 days (p < 0.001; OR: 2.56; 95% CI: 1.71–3.83), fever (p < 0.001; OR: 1.89; 95% CI: 1.38–2.59), pneumonia (p = 0.041; OR: 1.45; 95% CI: 1.01–2.09), and neurological diseases (p = 0.009; OR: 0.375; 95% CI: 0.18–0.78). (4) Conclusions: According to data gathered from cohorts of hospitalized patients, HCWs, and MP, before the widespread availability of COVID-19 vaccines in Serbia, we can conclude that predictors of positive PCR SARS-CoV-2 test results in MP and HCWs were similar. Accurate estimates of COVID-19 in different population groups are important for health authorities.
PB  - MDPI
T2  - International Journal of Environmental Research and Public Health
T1  - Epidemiological Predictors of Positive SARS-CoV-2 Polymerase Chain Reaction Test in Three Cohorts: Hospitalized Patients, Healthcare Workers, and Military Population, Serbia, 2020
IS  - 4
SP  - 3601
VL  - 20
DO  - 10.3390/ijerph20043601
ER  - 

@article{
author = "Šuljagić, Vesna and Đurić-Petković, Danijela and Lazić, Srdan and Mladenović, Jovan and Rakonjac, Bojan and Opačić, Dolores and Ljubenović, Nenad and Milojković, Biljana and Radojević, Katarina and Nenezić, Ivana and Rančić, Nemanja",
year = "2023",
abstract = "Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its resulting coronavirus disease 2019 (COVID-19) has caused a fast-moving pandemic. Diagnostic testing, aimed to identify patients infected with SARS-CoV-2, plays a key role in controlling the COVID-19 pandemic in different populations. (2) Methods: This retrospective cohort study aimed to investigate predictors associated with positive polymerase chain reaction (PCR) SARS-CoV-2 test results in hospitalized patients, healthcare workers (HCWs), and military personnel (MP) during 2020, before the widespread availability of COVID-19 vaccines. Persons with a positive test result were compared with persons with a negative test result in three cohorts during the study period. (3) Results: A total of 6912 respondents were tested, and 1334 (19.3%) of them had positive PCR SARS-CoV-2 test results. Contact with a known COVID-19 case within 14 days (p < 0.001; OR: 1.48; 95% CI: 1.25–1.76), fever (p < 0.001; OR: 3.66; 95% CI: 3.04–4.41), cough (p < 0.001; OR: 1.91; 95% CI: 1.59–2.30), headache (p = 0.028; OR: 1.24; 95% CI: 1.02–1.50), and myalgia/arthralgia (p < 0.001; OR: 1.99; 95% CI: 1.65–2.42) were independently associated with positive PCR SARS-CoV-2 test results in the cohort of MP. Furthermore, fever (p < 0.001; OR: 2.75; 95% CI: 1.83–4.13), cough (p < 0.001; OR: 2.04; 95% CI: 1.32–3.13), headache (p = 0.008; OR: 1.76; 95% CI: 1.15–2.68), and myalgia/arthralgia (p = 0.039; OR: 1.58; 95% CI: 1.02–2.45) were independently associated with positive PCR SARS-CoV-2 test results in the cohort of HCWs. Moreover, independent predictors of positive PCR SARS-CoV-2 test results in hospitalized patients were contact with a known COVID-19 case within 14 days (p < 0.001; OR: 2.56; 95% CI: 1.71–3.83), fever (p < 0.001; OR: 1.89; 95% CI: 1.38–2.59), pneumonia (p = 0.041; OR: 1.45; 95% CI: 1.01–2.09), and neurological diseases (p = 0.009; OR: 0.375; 95% CI: 0.18–0.78). (4) Conclusions: According to data gathered from cohorts of hospitalized patients, HCWs, and MP, before the widespread availability of COVID-19 vaccines in Serbia, we can conclude that predictors of positive PCR SARS-CoV-2 test results in MP and HCWs were similar. Accurate estimates of COVID-19 in different population groups are important for health authorities.",
publisher = "MDPI",
journal = "International Journal of Environmental Research and Public Health",
title = "Epidemiological Predictors of Positive SARS-CoV-2 Polymerase Chain Reaction Test in Three Cohorts: Hospitalized Patients, Healthcare Workers, and Military Population, Serbia, 2020",
number = "4",
pages = "3601",
volume = "20",
doi = "10.3390/ijerph20043601"
}

Šuljagić, V., Đurić-Petković, D., Lazić, S., Mladenović, J., Rakonjac, B., Opačić, D., Ljubenović, N., Milojković, B., Radojević, K., Nenezić, I.,& Rančić, N.. (2023). Epidemiological Predictors of Positive SARS-CoV-2 Polymerase Chain Reaction Test in Three Cohorts: Hospitalized Patients, Healthcare Workers, and Military Population, Serbia, 2020. in International Journal of Environmental Research and Public Health
MDPI., 20(4), 3601.
https://doi.org/10.3390/ijerph20043601

Šuljagić V, Đurić-Petković D, Lazić S, Mladenović J, Rakonjac B, Opačić D, Ljubenović N, Milojković B, Radojević K, Nenezić I, Rančić N. Epidemiological Predictors of Positive SARS-CoV-2 Polymerase Chain Reaction Test in Three Cohorts: Hospitalized Patients, Healthcare Workers, and Military Population, Serbia, 2020. in International Journal of Environmental Research and Public Health. 2023;20(4):3601.
doi:10.3390/ijerph20043601 .

Šuljagić, Vesna, Đurić-Petković, Danijela, Lazić, Srdan, Mladenović, Jovan, Rakonjac, Bojan, Opačić, Dolores, Ljubenović, Nenad, Milojković, Biljana, Radojević, Katarina, Nenezić, Ivana, Rančić, Nemanja, "Epidemiological Predictors of Positive SARS-CoV-2 Polymerase Chain Reaction Test in Three Cohorts: Hospitalized Patients, Healthcare Workers, and Military Population, Serbia, 2020" in International Journal of Environmental Research and Public Health, 20, no. 4 (2023):3601,
https://doi.org/10.3390/ijerph20043601 . .

TY  - JOUR
AU  - Nikolić, Valentina
AU  - Stajković, Novica
AU  - Stamenković, Gorana
AU  - Čekanac, Radovan
AU  - Marušić, Predrag
AU  - Jovanović, N.
AU  - Krstić, Milena
AU  - Mladenović, Jovan
AU  - Siljić, Marina
AU  - Gligić, Ana
AU  - Stanojević, Maja
PY  - 2014
UR  - http://intor.torlakinstitut.com/handle/123456789/405
AB  - The Dobrava-Belgrade virus (DOBV) is a member of the Bunyaviridae family, genus Hantavirus, possessing a single-stranded RNA genome consisting of three segments, designated L (large), M (medium) and S (small). In this study, we present phylogenetic analysis of a newly detected DOBV strain isolated from Apodemus agrarius. Analysis was based on partial L and S segment sequences, in comparison to previously published DOBV sequences from Serbia and elsewhere. A phylogenetic tree based on partial S segment revealed local geographical clustering of DOBV sequences from Serbia, unrelated to host (rodent or human). The topology of the phylogenetic tree was confirmed with a high percent of completely or partially resolved quartets in likelihood-mapping analysis, whereas no evidence of possible recombination in the examined S segment data set was found.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - Comparative phylogenetic analysis of Dobrava-Belgrade virus l and s genetic segments isolated from an animal reservoir in Serbia
EP  - 506
IS  - 2
SP  - 497
VL  - 66
DO  - 10.2298/ABS1402497N
ER  - 

@article{
author = "Nikolić, Valentina and Stajković, Novica and Stamenković, Gorana and Čekanac, Radovan and Marušić, Predrag and Jovanović, N. and Krstić, Milena and Mladenović, Jovan and Siljić, Marina and Gligić, Ana and Stanojević, Maja",
year = "2014",
abstract = "The Dobrava-Belgrade virus (DOBV) is a member of the Bunyaviridae family, genus Hantavirus, possessing a single-stranded RNA genome consisting of three segments, designated L (large), M (medium) and S (small). In this study, we present phylogenetic analysis of a newly detected DOBV strain isolated from Apodemus agrarius. Analysis was based on partial L and S segment sequences, in comparison to previously published DOBV sequences from Serbia and elsewhere. A phylogenetic tree based on partial S segment revealed local geographical clustering of DOBV sequences from Serbia, unrelated to host (rodent or human). The topology of the phylogenetic tree was confirmed with a high percent of completely or partially resolved quartets in likelihood-mapping analysis, whereas no evidence of possible recombination in the examined S segment data set was found.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "Comparative phylogenetic analysis of Dobrava-Belgrade virus l and s genetic segments isolated from an animal reservoir in Serbia",
pages = "506-497",
number = "2",
volume = "66",
doi = "10.2298/ABS1402497N"
}

Nikolić, V., Stajković, N., Stamenković, G., Čekanac, R., Marušić, P., Jovanović, N., Krstić, M., Mladenović, J., Siljić, M., Gligić, A.,& Stanojević, M.. (2014). Comparative phylogenetic analysis of Dobrava-Belgrade virus l and s genetic segments isolated from an animal reservoir in Serbia. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 66(2), 497-506.
https://doi.org/10.2298/ABS1402497N

Nikolić V, Stajković N, Stamenković G, Čekanac R, Marušić P, Jovanović N, Krstić M, Mladenović J, Siljić M, Gligić A, Stanojević M. Comparative phylogenetic analysis of Dobrava-Belgrade virus l and s genetic segments isolated from an animal reservoir in Serbia. in Archives of Biological Sciences. 2014;66(2):497-506.
doi:10.2298/ABS1402497N .

Nikolić, Valentina, Stajković, Novica, Stamenković, Gorana, Čekanac, Radovan, Marušić, Predrag, Jovanović, N., Krstić, Milena, Mladenović, Jovan, Siljić, Marina, Gligić, Ana, Stanojević, Maja, "Comparative phylogenetic analysis of Dobrava-Belgrade virus l and s genetic segments isolated from an animal reservoir in Serbia" in Archives of Biological Sciences, 66, no. 2 (2014):497-506,
https://doi.org/10.2298/ABS1402497N . .

TY  - JOUR
AU  - Mladenović, Jovan
AU  - Čekanac, Radovan
AU  - Lazić, Srđan
AU  - Jadranin, Željko
AU  - Tasić, Dimitrije
AU  - Nedeljković, Jasminka
AU  - Pavlović, Miroslav
PY  - 2013
UR  - http://intor.torlakinstitut.com/handle/123456789/371
AB  - Background/Aim. The first cases of the pandemic pH1N1 influenza virus infection was observed in the United States and Mexico in April 2009 and the first laboratory confirmed case in Serbia was registered in June 2009. The aim of this paper was to report on the investigation of the first confirmed outbreak of the 2009 pandemic H1N1 influenza in Serbia and to describe the clinical and epidemiologic findings from this investigation. Methods. Descriptive and analytical epidemiological methods were used. Data were collected from medical records of the Military School students and epidemiological questionnaire. Pandemic H1N1 infection was initially confirmed by the RT-PCR assay in nasopharyngeal and oropharyngeal swabs and subsequently by the complement fixation test in serum samples. Results. The attack rate of acute respiratory illness was 70.8% (204/288). Pandemic H1N1 virus infection was confirmed in 44 of 82 tested cases of acute respiratory illness (53.7%) The most common clinical manifestations of pandemic influenza H1N1 were fever (88.6%), cough (61.4%), malaise (38.6%), runny nose (36.4%), headache (29.6%), sore throat (20.5%) and muscle pain (15.9%). Conclusion. The findings from this investigation suggest that pandemic H1N1 influenza in a high military school was widespread but did not cause severe illness.
AB  - Uvod/Cilj. Prvi slučajevi pandemijske infekcije virusom influence pH1N1 ustanovljeni su u Americi i Meksiku u aprilu 2009. a u Srbiji prvi laboratorijski potvrđen slučaj registrovan je u junu 2009. godine. Cilj rada bio je da se prikaže istraživanje prve dokazane epidemije pandemijske influence H1N1 u Srbiji i opišu klinički i epidemiološki nalazi iz ovog istraživanja. Metode. Primenjen je deskriptivni i analitički epidemiološki metod. Izvor podataka bila je medicinska dokumentacija učenika Vojne gimnazije i epidemiološki upitnik. Infekcija pandemijskim virusom H1N1 prvo je dokazana pomoću RT-PCR u nazofaringealnim i orofaringealnim brisevima, a zatim i reakcijom vezivanja komlementa u uzorcima seruma. Rezultati. Stopa javljanja akutnog respiratornog oboljenja iznosila je 70.8% (204/288). Infekcija pandemijskim H1N1 virusom potvrđena je kod 44 od 82 testiranih slučajeva akutnog respiratornog oboljenja (53,7%). Najčešće kliničke manifestacije pandemijske influence H1N1 bile su povišena temperatura (88,6%), kašalj (61,4%), malaksalost (38,6%), rinitis (36,4%), glavobolja (29,6%), gušobolja (20,5%) i bol u mišićima (15,9%). Zaključak. Rezultati ovog istraživanja ukazuju da je pandemijska influenca H1N1 bila raširena u Vojnoj gimnaziji, ali da nije izazvala teške forme oboljenja.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Pandemic influenza H1N1 outbreak in the Military School
T1  - Epidemija pandemijskog gripa H1N1 u Vojnoj gimnaziji
EP  - 585
IS  - 6
SP  - 580
VL  - 70
DO  - 10.2298/VSP1306580M
ER  - 

@article{
author = "Mladenović, Jovan and Čekanac, Radovan and Lazić, Srđan and Jadranin, Željko and Tasić, Dimitrije and Nedeljković, Jasminka and Pavlović, Miroslav",
year = "2013",
abstract = "Background/Aim. The first cases of the pandemic pH1N1 influenza virus infection was observed in the United States and Mexico in April 2009 and the first laboratory confirmed case in Serbia was registered in June 2009. The aim of this paper was to report on the investigation of the first confirmed outbreak of the 2009 pandemic H1N1 influenza in Serbia and to describe the clinical and epidemiologic findings from this investigation. Methods. Descriptive and analytical epidemiological methods were used. Data were collected from medical records of the Military School students and epidemiological questionnaire. Pandemic H1N1 infection was initially confirmed by the RT-PCR assay in nasopharyngeal and oropharyngeal swabs and subsequently by the complement fixation test in serum samples. Results. The attack rate of acute respiratory illness was 70.8% (204/288). Pandemic H1N1 virus infection was confirmed in 44 of 82 tested cases of acute respiratory illness (53.7%) The most common clinical manifestations of pandemic influenza H1N1 were fever (88.6%), cough (61.4%), malaise (38.6%), runny nose (36.4%), headache (29.6%), sore throat (20.5%) and muscle pain (15.9%). Conclusion. The findings from this investigation suggest that pandemic H1N1 influenza in a high military school was widespread but did not cause severe illness., Uvod/Cilj. Prvi slučajevi pandemijske infekcije virusom influence pH1N1 ustanovljeni su u Americi i Meksiku u aprilu 2009. a u Srbiji prvi laboratorijski potvrđen slučaj registrovan je u junu 2009. godine. Cilj rada bio je da se prikaže istraživanje prve dokazane epidemije pandemijske influence H1N1 u Srbiji i opišu klinički i epidemiološki nalazi iz ovog istraživanja. Metode. Primenjen je deskriptivni i analitički epidemiološki metod. Izvor podataka bila je medicinska dokumentacija učenika Vojne gimnazije i epidemiološki upitnik. Infekcija pandemijskim virusom H1N1 prvo je dokazana pomoću RT-PCR u nazofaringealnim i orofaringealnim brisevima, a zatim i reakcijom vezivanja komlementa u uzorcima seruma. Rezultati. Stopa javljanja akutnog respiratornog oboljenja iznosila je 70.8% (204/288). Infekcija pandemijskim H1N1 virusom potvrđena je kod 44 od 82 testiranih slučajeva akutnog respiratornog oboljenja (53,7%). Najčešće kliničke manifestacije pandemijske influence H1N1 bile su povišena temperatura (88,6%), kašalj (61,4%), malaksalost (38,6%), rinitis (36,4%), glavobolja (29,6%), gušobolja (20,5%) i bol u mišićima (15,9%). Zaključak. Rezultati ovog istraživanja ukazuju da je pandemijska influenca H1N1 bila raširena u Vojnoj gimnaziji, ali da nije izazvala teške forme oboljenja.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Pandemic influenza H1N1 outbreak in the Military School, Epidemija pandemijskog gripa H1N1 u Vojnoj gimnaziji",
pages = "585-580",
number = "6",
volume = "70",
doi = "10.2298/VSP1306580M"
}

Mladenović, J., Čekanac, R., Lazić, S., Jadranin, Ž., Tasić, D., Nedeljković, J.,& Pavlović, M.. (2013). Pandemic influenza H1N1 outbreak in the Military School. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 70(6), 580-585.
https://doi.org/10.2298/VSP1306580M

Mladenović J, Čekanac R, Lazić S, Jadranin Ž, Tasić D, Nedeljković J, Pavlović M. Pandemic influenza H1N1 outbreak in the Military School. in Vojnosanitetski pregled. 2013;70(6):580-585.
doi:10.2298/VSP1306580M .

Mladenović, Jovan, Čekanac, Radovan, Lazić, Srđan, Jadranin, Željko, Tasić, Dimitrije, Nedeljković, Jasminka, Pavlović, Miroslav, "Pandemic influenza H1N1 outbreak in the Military School" in Vojnosanitetski pregled, 70, no. 6 (2013):580-585,
https://doi.org/10.2298/VSP1306580M . .