TY  - JOUR
AU  - Bedoui, Sammy
AU  - Kromer, Andreas
AU  - Gebhardt, Thomas
AU  - Jacobs, Roland
AU  - Raber, Kerstin
AU  - Dimitrijević, Mirjana
AU  - Heine, Joern
AU  - von Hoersten, Stephan
PY  - 2008
UR  - http://intor.torlakinstitut.com/handle/123456789/252
AB  - Despite a continuously growing body of evidence highlighting the role of NPY in the immune system, surprisingly little is known about its ability to alter human leukocyte function. We therefore set out to examine NPY receptor expression and functional effects of NPY in freshly isolated human neutrophils. Our results not only demonstrate for the first time the presence of specific NPY receptors on human neutrophils, but also unveil of how these receptors differentially modulate critical functions of neutrophils such as phagocytosis of bacteria as well as the release of reactive oxygen species. (C) 2008 Elsevier B.V. All rights reserved.
PB  - Elsevier Science Bv, Amsterdam
T2  - Journal of Neuroimmunology
T1  - Neuropeptide Y receptor-specifically modulates human neutrophil function
EP  - 95
IS  - 1-2
SP  - 88
VL  - 195
DO  - 10.1016/j.jneuroim.2008.01.012
ER  - 

@article{
author = "Bedoui, Sammy and Kromer, Andreas and Gebhardt, Thomas and Jacobs, Roland and Raber, Kerstin and Dimitrijević, Mirjana and Heine, Joern and von Hoersten, Stephan",
year = "2008",
abstract = "Despite a continuously growing body of evidence highlighting the role of NPY in the immune system, surprisingly little is known about its ability to alter human leukocyte function. We therefore set out to examine NPY receptor expression and functional effects of NPY in freshly isolated human neutrophils. Our results not only demonstrate for the first time the presence of specific NPY receptors on human neutrophils, but also unveil of how these receptors differentially modulate critical functions of neutrophils such as phagocytosis of bacteria as well as the release of reactive oxygen species. (C) 2008 Elsevier B.V. All rights reserved.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Neuroimmunology",
title = "Neuropeptide Y receptor-specifically modulates human neutrophil function",
pages = "95-88",
number = "1-2",
volume = "195",
doi = "10.1016/j.jneuroim.2008.01.012"
}

Bedoui, S., Kromer, A., Gebhardt, T., Jacobs, R., Raber, K., Dimitrijević, M., Heine, J.,& von Hoersten, S.. (2008). Neuropeptide Y receptor-specifically modulates human neutrophil function. in Journal of Neuroimmunology
Elsevier Science Bv, Amsterdam., 195(1-2), 88-95.
https://doi.org/10.1016/j.jneuroim.2008.01.012

Bedoui S, Kromer A, Gebhardt T, Jacobs R, Raber K, Dimitrijević M, Heine J, von Hoersten S. Neuropeptide Y receptor-specifically modulates human neutrophil function. in Journal of Neuroimmunology. 2008;195(1-2):88-95.
doi:10.1016/j.jneuroim.2008.01.012 .

Bedoui, Sammy, Kromer, Andreas, Gebhardt, Thomas, Jacobs, Roland, Raber, Kerstin, Dimitrijević, Mirjana, Heine, Joern, von Hoersten, Stephan, "Neuropeptide Y receptor-specifically modulates human neutrophil function" in Journal of Neuroimmunology, 195, no. 1-2 (2008):88-95,
https://doi.org/10.1016/j.jneuroim.2008.01.012 . .

TY  - JOUR
AU  - Nave, H.
AU  - Bedoui, Sammy
AU  - Moenter, F.
AU  - Steffens, J.
AU  - Felies, M.
AU  - Gebhardt, Thomas
AU  - Straub, RH
AU  - Pabst, R.
AU  - Dimitrijević, Mirjana
AU  - Stanojević, Stanislava
AU  - von Hoersten, Stephan
PY  - 2004
UR  - http://intor.torlakinstitut.com/handle/123456789/175
AB  - Neuropeptide Y (NPY) increases survival in experimental septic shock, which might be mediated by cardiovascular and/or immunological effects. To study the latter hypothesis, we monitored blood leukocyte subsets over 96 h after intravenous (i.v.) application of LPS in chronically i.v.-cannulated rats. LPS induced a dramatic leukopenia at 4 h after challenge, which was blunted in NPY-treated animals by stabilizing granulocyte and T-lymphocyte numbers. In addition, NPY treatment prevented tissue immigration of monocytes at early time points and consecutively mobilized activated monocytes from the third day after challenge. RT-PCR and in vitro adhesion studies provided evidence for a NPY Y-2 receptor-mediated effect on monocytes. Thus, NPY treatment has profound receptor-specific effects on the migration and adhesion of leukocytes under endotoxemic conditions. (C) 2004 Elsevier B.V. All rights reserved.
PB  - Elsevier, Amsterdam
T2  - Journal of Neuroimmunology
T1  - Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y-2 receptor activation
EP  - 12
IS  - 1-2
SP  - 1
VL  - 155
DO  - 10.1016/j.jneuroim.2004.05.009
ER  - 

@article{
author = "Nave, H. and Bedoui, Sammy and Moenter, F. and Steffens, J. and Felies, M. and Gebhardt, Thomas and Straub, RH and Pabst, R. and Dimitrijević, Mirjana and Stanojević, Stanislava and von Hoersten, Stephan",
year = "2004",
abstract = "Neuropeptide Y (NPY) increases survival in experimental septic shock, which might be mediated by cardiovascular and/or immunological effects. To study the latter hypothesis, we monitored blood leukocyte subsets over 96 h after intravenous (i.v.) application of LPS in chronically i.v.-cannulated rats. LPS induced a dramatic leukopenia at 4 h after challenge, which was blunted in NPY-treated animals by stabilizing granulocyte and T-lymphocyte numbers. In addition, NPY treatment prevented tissue immigration of monocytes at early time points and consecutively mobilized activated monocytes from the third day after challenge. RT-PCR and in vitro adhesion studies provided evidence for a NPY Y-2 receptor-mediated effect on monocytes. Thus, NPY treatment has profound receptor-specific effects on the migration and adhesion of leukocytes under endotoxemic conditions. (C) 2004 Elsevier B.V. All rights reserved.",
publisher = "Elsevier, Amsterdam",
journal = "Journal of Neuroimmunology",
title = "Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y-2 receptor activation",
pages = "12-1",
number = "1-2",
volume = "155",
doi = "10.1016/j.jneuroim.2004.05.009"
}

Nave, H., Bedoui, S., Moenter, F., Steffens, J., Felies, M., Gebhardt, T., Straub, R., Pabst, R., Dimitrijević, M., Stanojević, S.,& von Hoersten, S.. (2004). Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y-2 receptor activation. in Journal of Neuroimmunology
Elsevier, Amsterdam., 155(1-2), 1-12.
https://doi.org/10.1016/j.jneuroim.2004.05.009

Nave H, Bedoui S, Moenter F, Steffens J, Felies M, Gebhardt T, Straub R, Pabst R, Dimitrijević M, Stanojević S, von Hoersten S. Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y-2 receptor activation. in Journal of Neuroimmunology. 2004;155(1-2):1-12.
doi:10.1016/j.jneuroim.2004.05.009 .

Nave, H., Bedoui, Sammy, Moenter, F., Steffens, J., Felies, M., Gebhardt, Thomas, Straub, RH, Pabst, R., Dimitrijević, Mirjana, Stanojević, Stanislava, von Hoersten, Stephan, "Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y-2 receptor activation" in Journal of Neuroimmunology, 155, no. 1-2 (2004):1-12,
https://doi.org/10.1016/j.jneuroim.2004.05.009 . .