TY  - JOUR
AU  - Stanojević, Maja
AU  - Nikolić, V.
AU  - Stajković, Novica
AU  - Stamenković, Gorana
AU  - Božović, Bojana
AU  - Čekanac, Radovan
AU  - Marušić, Predrag
AU  - Gligić, Ana
PY  - 2015
UR  - http://intor.torlakinstitut.com/handle/123456789/439
AB  - Hantaviruses are endemic in the Balkans, particularly in Serbia, where sporadic cases and/or outbreaks of hantaviral human disease have been reported repeatedly, and evidenced serologically. Here, we present genetic detection of Dobrava-Belgrade virus (DOBV) hantaviral sequences in wild rodents trapped in central Serbia. All the animals were pre-screened serologically by indirect immunofluorescence (IF) test and only those with a positive finding of hantaviral antigens were further tested by polymerase chain reaction. Of the total of 104 trapped animals, 20 were found to be IF positive and of those three were positive for hantaviral RNA: one Microtus arvalis for Tula virus, and one each of Apodemus agrarius and Glis glis for DOBV. Phylogenetic analysis of the obtained sequences implies putative DOBV spillover infection of A. agrarius and G. glis from Apodemus flavicollis. However, future investigations should help to identify the most common natural host and geographical distribution of DOBV in its reservoir hosts in Serbia.
PB  - Cambridge Univ Press, New York
T2  - Epidemiology and Infection
T1  - Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia
EP  - 404
IS  - 2
SP  - 400
VL  - 143
DO  - 10.1017/S0950268814001010
ER  - 

@article{
author = "Stanojević, Maja and Nikolić, V. and Stajković, Novica and Stamenković, Gorana and Božović, Bojana and Čekanac, Radovan and Marušić, Predrag and Gligić, Ana",
year = "2015",
abstract = "Hantaviruses are endemic in the Balkans, particularly in Serbia, where sporadic cases and/or outbreaks of hantaviral human disease have been reported repeatedly, and evidenced serologically. Here, we present genetic detection of Dobrava-Belgrade virus (DOBV) hantaviral sequences in wild rodents trapped in central Serbia. All the animals were pre-screened serologically by indirect immunofluorescence (IF) test and only those with a positive finding of hantaviral antigens were further tested by polymerase chain reaction. Of the total of 104 trapped animals, 20 were found to be IF positive and of those three were positive for hantaviral RNA: one Microtus arvalis for Tula virus, and one each of Apodemus agrarius and Glis glis for DOBV. Phylogenetic analysis of the obtained sequences implies putative DOBV spillover infection of A. agrarius and G. glis from Apodemus flavicollis. However, future investigations should help to identify the most common natural host and geographical distribution of DOBV in its reservoir hosts in Serbia.",
publisher = "Cambridge Univ Press, New York",
journal = "Epidemiology and Infection",
title = "Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia",
pages = "404-400",
number = "2",
volume = "143",
doi = "10.1017/S0950268814001010"
}

Stanojević, M., Nikolić, V., Stajković, N., Stamenković, G., Božović, B., Čekanac, R., Marušić, P.,& Gligić, A.. (2015). Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia. in Epidemiology and Infection
Cambridge Univ Press, New York., 143(2), 400-404.
https://doi.org/10.1017/S0950268814001010

Stanojević M, Nikolić V, Stajković N, Stamenković G, Božović B, Čekanac R, Marušić P, Gligić A. Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia. in Epidemiology and Infection. 2015;143(2):400-404.
doi:10.1017/S0950268814001010 .

Stanojević, Maja, Nikolić, V., Stajković, Novica, Stamenković, Gorana, Božović, Bojana, Čekanac, Radovan, Marušić, Predrag, Gligić, Ana, "Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia" in Epidemiology and Infection, 143, no. 2 (2015):400-404,
https://doi.org/10.1017/S0950268814001010 . .

TY  - JOUR
AU  - Fernandez-García, M.D.
AU  - Negredo, A.
AU  - Papa, Anna
AU  - Donoso-Mantke, O.
AU  - Niedrig, M.
AU  - Zeller, H.
AU  - Tenorio, A.
AU  - Franco, L.
AU  - Aberle, S.
AU  - van Esbroeck, M.
AU  - Christova, I.
AU  - Markotić, A.
AU  - Kurolt, I.-C.
AU  - Zelena, H.
AU  - Golovljova, I.
AU  - Pannetier, D.
AU  - Charrel, R.
AU  - Schmidt-Chanasit, J.
AU  - Wölfel, R.
AU  - Capobianchi, M.R.
AU  - Jakupi, X.
AU  - Storozenko, J.
AU  - Griskevicius, A.
AU  - Bosevska, G.
AU  - Muscat, C.
AU  - Schutten, M.
AU  - Dudman, S.G.
AU  - Alves, M.J.
AU  - Ceianu, C.
AU  - Platonov, A.
AU  - Božović, Bojana
AU  - Klempa, B.
AU  - Avsić, T.
AU  - Tenorio, A.
AU  - Lundkvist, A.
AU  - Cherpillod, P.
AU  - Korukluoglu, G.
AU  - Brown, D.
AU  - Brooks, T.
PY  - 2014
UR  - http://intor.torlakinstitut.com/handle/123456789/412
AB  - Crimean-Congo haemorrhagic fever (CCHF) is an infectious viral disease that has (re-)emerged in the last decade in south-eastern Europe, and there is a risk for further geographical expansion to western Europe. Here we report the results of a survey covering 28 countries, conducted in 2012 among the member laboratories of the European Network for Diagnostics of 'Imported' Viral Diseases (ENIVD) to assess laboratory preparedness and response capacities for CCHF. The answers of 31 laboratories of the European region regarding CCHF case definition, training necessity, biosafety, quality assurance and diagnostic tests are presented. In addition, we identified the lack of a Regional Reference Expert Laboratory in or near endemic areas. Moreover, a comprehensive review of the biosafety level suitable to the reality of endemic areas is needed. These issues are challenges that should be addressed by European public health authorities. However, all respondent laboratories have suitable diagnostic capacities for the current situation.
PB  - European Centre for Disease Prevention and Control (ECDC)
T2  - Eurosurveillance
T1  - European survey on laboratory preparedness, response and diagnostic capacity for crimean-congo haemorrhagic fever, 2012
IS  - 26
VL  - 19
DO  - 10.2807/1560-7917.ES2014.19.26.20844
ER  - 

@article{
author = "Fernandez-García, M.D. and Negredo, A. and Papa, Anna and Donoso-Mantke, O. and Niedrig, M. and Zeller, H. and Tenorio, A. and Franco, L. and Aberle, S. and van Esbroeck, M. and Christova, I. and Markotić, A. and Kurolt, I.-C. and Zelena, H. and Golovljova, I. and Pannetier, D. and Charrel, R. and Schmidt-Chanasit, J. and Wölfel, R. and Capobianchi, M.R. and Jakupi, X. and Storozenko, J. and Griskevicius, A. and Bosevska, G. and Muscat, C. and Schutten, M. and Dudman, S.G. and Alves, M.J. and Ceianu, C. and Platonov, A. and Božović, Bojana and Klempa, B. and Avsić, T. and Tenorio, A. and Lundkvist, A. and Cherpillod, P. and Korukluoglu, G. and Brown, D. and Brooks, T.",
year = "2014",
abstract = "Crimean-Congo haemorrhagic fever (CCHF) is an infectious viral disease that has (re-)emerged in the last decade in south-eastern Europe, and there is a risk for further geographical expansion to western Europe. Here we report the results of a survey covering 28 countries, conducted in 2012 among the member laboratories of the European Network for Diagnostics of 'Imported' Viral Diseases (ENIVD) to assess laboratory preparedness and response capacities for CCHF. The answers of 31 laboratories of the European region regarding CCHF case definition, training necessity, biosafety, quality assurance and diagnostic tests are presented. In addition, we identified the lack of a Regional Reference Expert Laboratory in or near endemic areas. Moreover, a comprehensive review of the biosafety level suitable to the reality of endemic areas is needed. These issues are challenges that should be addressed by European public health authorities. However, all respondent laboratories have suitable diagnostic capacities for the current situation.",
publisher = "European Centre for Disease Prevention and Control (ECDC)",
journal = "Eurosurveillance",
title = "European survey on laboratory preparedness, response and diagnostic capacity for crimean-congo haemorrhagic fever, 2012",
number = "26",
volume = "19",
doi = "10.2807/1560-7917.ES2014.19.26.20844"
}

Fernandez-García, M.D., Negredo, A., Papa, A., Donoso-Mantke, O., Niedrig, M., Zeller, H., Tenorio, A., Franco, L., Aberle, S., van Esbroeck, M., Christova, I., Markotić, A., Kurolt, I.-C., Zelena, H., Golovljova, I., Pannetier, D., Charrel, R., Schmidt-Chanasit, J., Wölfel, R., Capobianchi, M.R., Jakupi, X., Storozenko, J., Griskevicius, A., Bosevska, G., Muscat, C., Schutten, M., Dudman, S.G., Alves, M.J., Ceianu, C., Platonov, A., Božović, B., Klempa, B., Avsić, T., Tenorio, A., Lundkvist, A., Cherpillod, P., Korukluoglu, G., Brown, D.,& Brooks, T.. (2014). European survey on laboratory preparedness, response and diagnostic capacity for crimean-congo haemorrhagic fever, 2012. in Eurosurveillance
European Centre for Disease Prevention and Control (ECDC)., 19(26).
https://doi.org/10.2807/1560-7917.ES2014.19.26.20844

Fernandez-García M, Negredo A, Papa A, Donoso-Mantke O, Niedrig M, Zeller H, Tenorio A, Franco L, Aberle S, van Esbroeck M, Christova I, Markotić A, Kurolt I, Zelena H, Golovljova I, Pannetier D, Charrel R, Schmidt-Chanasit J, Wölfel R, Capobianchi M, Jakupi X, Storozenko J, Griskevicius A, Bosevska G, Muscat C, Schutten M, Dudman S, Alves M, Ceianu C, Platonov A, Božović B, Klempa B, Avsić T, Tenorio A, Lundkvist A, Cherpillod P, Korukluoglu G, Brown D, Brooks T. European survey on laboratory preparedness, response and diagnostic capacity for crimean-congo haemorrhagic fever, 2012. in Eurosurveillance. 2014;19(26).
doi:10.2807/1560-7917.ES2014.19.26.20844 .

Fernandez-García, M.D., Negredo, A., Papa, Anna, Donoso-Mantke, O., Niedrig, M., Zeller, H., Tenorio, A., Franco, L., Aberle, S., van Esbroeck, M., Christova, I., Markotić, A., Kurolt, I.-C., Zelena, H., Golovljova, I., Pannetier, D., Charrel, R., Schmidt-Chanasit, J., Wölfel, R., Capobianchi, M.R., Jakupi, X., Storozenko, J., Griskevicius, A., Bosevska, G., Muscat, C., Schutten, M., Dudman, S.G., Alves, M.J., Ceianu, C., Platonov, A., Božović, Bojana, Klempa, B., Avsić, T., Tenorio, A., Lundkvist, A., Cherpillod, P., Korukluoglu, G., Brown, D., Brooks, T., "European survey on laboratory preparedness, response and diagnostic capacity for crimean-congo haemorrhagic fever, 2012" in Eurosurveillance, 19, no. 26 (2014),
https://doi.org/10.2807/1560-7917.ES2014.19.26.20844 . .

TY  - JOUR
AU  - Samardžić, Svetomir
AU  - Marinković, Tatjana
AU  - Marinković, Dragan
AU  - Đuricić, Bosiljka
AU  - Ristanović, Elizabeta
AU  - Simović, Tatjana
AU  - Lako, Branislav
AU  - Vukov, Biljana
AU  - Božović, Bojana
AU  - Gligić, Ana
PY  - 2008
UR  - http://intor.torlakinstitut.com/handle/123456789/258
AB  - We assayed the presence of antibodies specific for Rickettsia typhi, R. akari, and R. conorii in sera of persons from several localities in Serbia with different geographic, climatic, and lifestyle characteristics. Sera from 140 patients with unclear clinical symptoms and 273 healthy persons were tested for the presence of rickettsiae-specific antibodies by indirect immunofluorescence assay. In this study, for the first time we detected the presence of rickettsiae from the spotted fever group in Serbia. We detected the presence of antibodies against R. conorii in the samples from all tested localities. The proportion of positive cases was low in the plain agricultural areas but reached up to 23% in the mountain areas. We also observed a significant number of cases positive for antibodies against R. akari. Antibodies specific for the antigens of R. typhi were detected in only 2 samples from the municipality of Pec (Kosovo region). These findings contribute to the prevalence of Rickettsia species in Southeast Europe. Our study also revealed a dramatic lack of awareness of rickettsioses among medical personnel and pointed to the need for urgent measures that would help improve the current situation in the region.
PB  - Mary Ann Liebert, Inc, New Rochelle
T2  - Vector-Borne and Zoonotic Diseases
T1  - Prevalence of antibodies to Rickettsiae in different regions of Serbia
EP  - 224
IS  - 2
SP  - 219
VL  - 8
DO  - 10.1089/vbz.2007.0122
ER  - 

@article{
author = "Samardžić, Svetomir and Marinković, Tatjana and Marinković, Dragan and Đuricić, Bosiljka and Ristanović, Elizabeta and Simović, Tatjana and Lako, Branislav and Vukov, Biljana and Božović, Bojana and Gligić, Ana",
year = "2008",
abstract = "We assayed the presence of antibodies specific for Rickettsia typhi, R. akari, and R. conorii in sera of persons from several localities in Serbia with different geographic, climatic, and lifestyle characteristics. Sera from 140 patients with unclear clinical symptoms and 273 healthy persons were tested for the presence of rickettsiae-specific antibodies by indirect immunofluorescence assay. In this study, for the first time we detected the presence of rickettsiae from the spotted fever group in Serbia. We detected the presence of antibodies against R. conorii in the samples from all tested localities. The proportion of positive cases was low in the plain agricultural areas but reached up to 23% in the mountain areas. We also observed a significant number of cases positive for antibodies against R. akari. Antibodies specific for the antigens of R. typhi were detected in only 2 samples from the municipality of Pec (Kosovo region). These findings contribute to the prevalence of Rickettsia species in Southeast Europe. Our study also revealed a dramatic lack of awareness of rickettsioses among medical personnel and pointed to the need for urgent measures that would help improve the current situation in the region.",
publisher = "Mary Ann Liebert, Inc, New Rochelle",
journal = "Vector-Borne and Zoonotic Diseases",
title = "Prevalence of antibodies to Rickettsiae in different regions of Serbia",
pages = "224-219",
number = "2",
volume = "8",
doi = "10.1089/vbz.2007.0122"
}

Samardžić, S., Marinković, T., Marinković, D., Đuricić, B., Ristanović, E., Simović, T., Lako, B., Vukov, B., Božović, B.,& Gligić, A.. (2008). Prevalence of antibodies to Rickettsiae in different regions of Serbia. in Vector-Borne and Zoonotic Diseases
Mary Ann Liebert, Inc, New Rochelle., 8(2), 219-224.
https://doi.org/10.1089/vbz.2007.0122

Samardžić S, Marinković T, Marinković D, Đuricić B, Ristanović E, Simović T, Lako B, Vukov B, Božović B, Gligić A. Prevalence of antibodies to Rickettsiae in different regions of Serbia. in Vector-Borne and Zoonotic Diseases. 2008;8(2):219-224.
doi:10.1089/vbz.2007.0122 .

Samardžić, Svetomir, Marinković, Tatjana, Marinković, Dragan, Đuricić, Bosiljka, Ristanović, Elizabeta, Simović, Tatjana, Lako, Branislav, Vukov, Biljana, Božović, Bojana, Gligić, Ana, "Prevalence of antibodies to Rickettsiae in different regions of Serbia" in Vector-Borne and Zoonotic Diseases, 8, no. 2 (2008):219-224,
https://doi.org/10.1089/vbz.2007.0122 . .

TY  - JOUR
AU  - Gledović, Z.B.
AU  - Jeknić, A.S.
AU  - Grgurević, Anita
AU  - Rakočević, B.B.
AU  - Božović, Bojana
AU  - Mugosa, B.V.
PY  - 2008
UR  - http://intor.torlakinstitut.com/handle/123456789/267
AB  - The objective of the study was to analyze the epidemiological features of hemorrhagic fever with renal syndrome (HFRS) in Montenegro. The study included 169 cases of HFRS diagnosed in the period between 1995 and 2005 according to the clinical symptoms and serological confirmation. For the analysis of the demographic characteristics of the cases, as well as of the chronological and topographical features of the disease, a descriptive epidemiological method was employed. The average incidence rate in the observed period was 2.6 per 100,000. In the observed period, 8 people died; the average case fatality rate was 4.8% (range: 0.1-15%). Among the diseased persons, 116 were males and 53 were females; most of the cases were adults. The greatest number of HFRS cases occurred during the summer months. The highest incidence rates were registered in the northeastern, rural part of the country. The most frequent type of hantaviruses in Montenegro were Dobrava-Belgrade and Hantaan, carried by rodent species, i.e., the yellow-neck mouse and the striped-field mouse. It is likely that HFRS in Montenegro will become more common in the near future, unless public health control measures are taken.
PB  - Natl Inst Infectious Diseases, Tokyo
T2  - Japanese Journal of Infectious Diseases
T1  - Hemorrhagic fever with renal syndrome in Montenegro
EP  - 387
IS  - 5
SP  - 386
VL  - 61
UR  - https://hdl.handle.net/21.15107/rcub_intor_267
ER  - 

@article{
author = "Gledović, Z.B. and Jeknić, A.S. and Grgurević, Anita and Rakočević, B.B. and Božović, Bojana and Mugosa, B.V.",
year = "2008",
abstract = "The objective of the study was to analyze the epidemiological features of hemorrhagic fever with renal syndrome (HFRS) in Montenegro. The study included 169 cases of HFRS diagnosed in the period between 1995 and 2005 according to the clinical symptoms and serological confirmation. For the analysis of the demographic characteristics of the cases, as well as of the chronological and topographical features of the disease, a descriptive epidemiological method was employed. The average incidence rate in the observed period was 2.6 per 100,000. In the observed period, 8 people died; the average case fatality rate was 4.8% (range: 0.1-15%). Among the diseased persons, 116 were males and 53 were females; most of the cases were adults. The greatest number of HFRS cases occurred during the summer months. The highest incidence rates were registered in the northeastern, rural part of the country. The most frequent type of hantaviruses in Montenegro were Dobrava-Belgrade and Hantaan, carried by rodent species, i.e., the yellow-neck mouse and the striped-field mouse. It is likely that HFRS in Montenegro will become more common in the near future, unless public health control measures are taken.",
publisher = "Natl Inst Infectious Diseases, Tokyo",
journal = "Japanese Journal of Infectious Diseases",
title = "Hemorrhagic fever with renal syndrome in Montenegro",
pages = "387-386",
number = "5",
volume = "61",
url = "https://hdl.handle.net/21.15107/rcub_intor_267"
}

Gledović, Z.B., Jeknić, A.S., Grgurević, A., Rakočević, B.B., Božović, B.,& Mugosa, B.V.. (2008). Hemorrhagic fever with renal syndrome in Montenegro. in Japanese Journal of Infectious Diseases
Natl Inst Infectious Diseases, Tokyo., 61(5), 386-387.
https://hdl.handle.net/21.15107/rcub_intor_267

Gledović Z, Jeknić A, Grgurević A, Rakočević B, Božović B, Mugosa B. Hemorrhagic fever with renal syndrome in Montenegro. in Japanese Journal of Infectious Diseases. 2008;61(5):386-387.
https://hdl.handle.net/21.15107/rcub_intor_267 .

Gledović, Z.B., Jeknić, A.S., Grgurević, Anita, Rakočević, B.B., Božović, Bojana, Mugosa, B.V., "Hemorrhagic fever with renal syndrome in Montenegro" in Japanese Journal of Infectious Diseases, 61, no. 5 (2008):386-387,
https://hdl.handle.net/21.15107/rcub_intor_267 .

TY  - JOUR
AU  - Samardžić, Svetomir
AU  - Marinković, Dragan
AU  - Marinković, Tatjana
AU  - Simović, Tatjana
AU  - Božović, Bojana
AU  - Milić, Aleksandra
AU  - Vukov, Biljana
AU  - Gligić, Ana
PY  - 2007
UR  - http://intor.torlakinstitut.com/handle/123456789/236
AB  - The aim of our study were to examine the prevalence of Ehrlichia chaffeensis, etiological agent of Human Monocytotropic Ehrlichiosis, in population of Serbia we assayed the presence of specific antibodies in human sera by indirect immunofluorescence assay. Sera from 273 healthy persons and 138 patients with unclear rheumatoid and influenza-like clinical symptoms from several localities with different geographical, climatic and lifestyle characteristics were tested. In this survey, for the first time, we detected presence of Ehrlichia chaffeensis-specific antibodies in the sera of healthy volunteers from the mountain/forest areas of Serbia. In addition, our findings suggest that some of the patients with unclear clinical symptoms experienced the infection with Ehrlichia chaffeensis, and most probably suffered from Human Monocytotropic Ehrlichiosis. These findings contribute to the investigation of the prevalence of Ehrlichia chaffeensis in Southeast Europe. Our study also revealed lack of awareness of Ehrlichioses and points the urge for the measures that would help improving current situation in the region.
AB  - Cilj naše studije je bio da ispitamo prevalencu Ehrlichi-je chaffeensis, etiološkog uzročnika humane monocitotropične erlihioze u Srbiji utvrđivanjem prisustva specifičnih antitela u humanom serumu metodom indirektne imunofluoroscencije. Testirani su serumi 273 zdrave osobe i 138 pacijenata sa nejasnim reumatoidnim i gripu sličnim kliničkim simptomima iz različitih geografskih, klimatskim i socijalnih sredina. Na taj način smo po prvi put, detektovali prisustvo Ehrlichia chaffeensis-specifičnih antitela u serumu zdravih dobrovoljaca iz planinskih oblasti Srbije.Naš nalaz ukazuje da su neki od pacijenata sa nejasnim kliničkim simptomima bili izloženi infekciji sa Ehrlichijom chaffeensis najverovatnije oboleli od humane monocitotropične erlihioze. Ovaj nalaz doprinosi utvrđivanju prevalence Ehrlichije chaffeensis u jugoistočno Evropi. Naša studija je takođe otkrila da se ova bolest vrlo često previđa i ukazuje na mere koje bi poboljšale trenutnu situaciju u regionu.
PB  - Kliničko-bolnički centar Zemun, Beograd
T2  - Materia medica
T1  - Ehrlichia chaffeensis infection in different regions of Serbia
T1  - Infekcije Ehrlichi-om chaffeensis u različitim regionima Srbije
EP  - 14
IS  - 2
SP  - 10
VL  - 23
UR  - https://hdl.handle.net/21.15107/rcub_intor_236
ER  - 

@article{
author = "Samardžić, Svetomir and Marinković, Dragan and Marinković, Tatjana and Simović, Tatjana and Božović, Bojana and Milić, Aleksandra and Vukov, Biljana and Gligić, Ana",
year = "2007",
abstract = "The aim of our study were to examine the prevalence of Ehrlichia chaffeensis, etiological agent of Human Monocytotropic Ehrlichiosis, in population of Serbia we assayed the presence of specific antibodies in human sera by indirect immunofluorescence assay. Sera from 273 healthy persons and 138 patients with unclear rheumatoid and influenza-like clinical symptoms from several localities with different geographical, climatic and lifestyle characteristics were tested. In this survey, for the first time, we detected presence of Ehrlichia chaffeensis-specific antibodies in the sera of healthy volunteers from the mountain/forest areas of Serbia. In addition, our findings suggest that some of the patients with unclear clinical symptoms experienced the infection with Ehrlichia chaffeensis, and most probably suffered from Human Monocytotropic Ehrlichiosis. These findings contribute to the investigation of the prevalence of Ehrlichia chaffeensis in Southeast Europe. Our study also revealed lack of awareness of Ehrlichioses and points the urge for the measures that would help improving current situation in the region., Cilj naše studije je bio da ispitamo prevalencu Ehrlichi-je chaffeensis, etiološkog uzročnika humane monocitotropične erlihioze u Srbiji utvrđivanjem prisustva specifičnih antitela u humanom serumu metodom indirektne imunofluoroscencije. Testirani su serumi 273 zdrave osobe i 138 pacijenata sa nejasnim reumatoidnim i gripu sličnim kliničkim simptomima iz različitih geografskih, klimatskim i socijalnih sredina. Na taj način smo po prvi put, detektovali prisustvo Ehrlichia chaffeensis-specifičnih antitela u serumu zdravih dobrovoljaca iz planinskih oblasti Srbije.Naš nalaz ukazuje da su neki od pacijenata sa nejasnim kliničkim simptomima bili izloženi infekciji sa Ehrlichijom chaffeensis najverovatnije oboleli od humane monocitotropične erlihioze. Ovaj nalaz doprinosi utvrđivanju prevalence Ehrlichije chaffeensis u jugoistočno Evropi. Naša studija je takođe otkrila da se ova bolest vrlo često previđa i ukazuje na mere koje bi poboljšale trenutnu situaciju u regionu.",
publisher = "Kliničko-bolnički centar Zemun, Beograd",
journal = "Materia medica",
title = "Ehrlichia chaffeensis infection in different regions of Serbia, Infekcije Ehrlichi-om chaffeensis u različitim regionima Srbije",
pages = "14-10",
number = "2",
volume = "23",
url = "https://hdl.handle.net/21.15107/rcub_intor_236"
}

Samardžić, S., Marinković, D., Marinković, T., Simović, T., Božović, B., Milić, A., Vukov, B.,& Gligić, A.. (2007). Ehrlichia chaffeensis infection in different regions of Serbia. in Materia medica
Kliničko-bolnički centar Zemun, Beograd., 23(2), 10-14.
https://hdl.handle.net/21.15107/rcub_intor_236

Samardžić S, Marinković D, Marinković T, Simović T, Božović B, Milić A, Vukov B, Gligić A. Ehrlichia chaffeensis infection in different regions of Serbia. in Materia medica. 2007;23(2):10-14.
https://hdl.handle.net/21.15107/rcub_intor_236 .

Samardžić, Svetomir, Marinković, Dragan, Marinković, Tatjana, Simović, Tatjana, Božović, Bojana, Milić, Aleksandra, Vukov, Biljana, Gligić, Ana, "Ehrlichia chaffeensis infection in different regions of Serbia" in Materia medica, 23, no. 2 (2007):10-14,
https://hdl.handle.net/21.15107/rcub_intor_236 .

TY  - JOUR
AU  - Papa, Anna
AU  - Papadimitriou, E.
AU  - Božović, Bojana
AU  - Antoniadis, Antonis
PY  - 2005
UR  - http://intor.torlakinstitut.com/handle/123456789/199
AB  - Crimean-Congo hemorrhagic fever (CCHF) virus causes one of the most severe diseases in humans, with a mortality rate of up to 30%. It is transmitted to humans by the bite of hard ticks or by contact with blood or tissues from human patients or infected livestock. Balkan Peninsula is an endemic region of the disease, and sporadic cases or even outbreaks are observed every year. The M RNA segment encodes for the glycoprotein precursor of two surface glycoproteins Gn and Gc. Up to now complete M RNA CCHF virus sequences have been published from strains isolated in Nigeria, China, Pakistan, Tajikistan, and Russia. In the present study, the genetic characterization of the complete nucleotide sequence of the M RNA segment of a Balkan CCHF virus strain, Kosovo/9553/2001, isolated in summer of 2001 from a human fatal case in Kosovo is reported. This is the first published complete M nucleotide sequence of a CCHF virus strain isolated in Balkans. It was found that the Balkan strain is similar to the Russian strain, both strains differing from all other completely sequenced CCHF virus strains by approximately 22% at the nucleotide level forming an independent clade in the phylogenetic tree. (C) 2005 Wiley-Liss, Inc.
PB  - Wiley, Hoboken
T2  - Journal of Medical Virology
T1  - Genetic characterization of the M RNA segment of a Balkan Crimean-Congo hemorrhagic fever virus strain
EP  - 469
IS  - 3
SP  - 466
VL  - 75
DO  - 10.1002/jmv.20290
ER  - 

@article{
author = "Papa, Anna and Papadimitriou, E. and Božović, Bojana and Antoniadis, Antonis",
year = "2005",
abstract = "Crimean-Congo hemorrhagic fever (CCHF) virus causes one of the most severe diseases in humans, with a mortality rate of up to 30%. It is transmitted to humans by the bite of hard ticks or by contact with blood or tissues from human patients or infected livestock. Balkan Peninsula is an endemic region of the disease, and sporadic cases or even outbreaks are observed every year. The M RNA segment encodes for the glycoprotein precursor of two surface glycoproteins Gn and Gc. Up to now complete M RNA CCHF virus sequences have been published from strains isolated in Nigeria, China, Pakistan, Tajikistan, and Russia. In the present study, the genetic characterization of the complete nucleotide sequence of the M RNA segment of a Balkan CCHF virus strain, Kosovo/9553/2001, isolated in summer of 2001 from a human fatal case in Kosovo is reported. This is the first published complete M nucleotide sequence of a CCHF virus strain isolated in Balkans. It was found that the Balkan strain is similar to the Russian strain, both strains differing from all other completely sequenced CCHF virus strains by approximately 22% at the nucleotide level forming an independent clade in the phylogenetic tree. (C) 2005 Wiley-Liss, Inc.",
publisher = "Wiley, Hoboken",
journal = "Journal of Medical Virology",
title = "Genetic characterization of the M RNA segment of a Balkan Crimean-Congo hemorrhagic fever virus strain",
pages = "469-466",
number = "3",
volume = "75",
doi = "10.1002/jmv.20290"
}

Papa, A., Papadimitriou, E., Božović, B.,& Antoniadis, A.. (2005). Genetic characterization of the M RNA segment of a Balkan Crimean-Congo hemorrhagic fever virus strain. in Journal of Medical Virology
Wiley, Hoboken., 75(3), 466-469.
https://doi.org/10.1002/jmv.20290

Papa A, Papadimitriou E, Božović B, Antoniadis A. Genetic characterization of the M RNA segment of a Balkan Crimean-Congo hemorrhagic fever virus strain. in Journal of Medical Virology. 2005;75(3):466-469.
doi:10.1002/jmv.20290 .

Papa, Anna, Papadimitriou, E., Božović, Bojana, Antoniadis, Antonis, "Genetic characterization of the M RNA segment of a Balkan Crimean-Congo hemorrhagic fever virus strain" in Journal of Medical Virology, 75, no. 3 (2005):466-469,
https://doi.org/10.1002/jmv.20290 . .

TY  - JOUR
AU  - Papa, Anna
AU  - Božović, Bojana
AU  - Pavlidou, V.
AU  - Papadimitriou, E.
AU  - Pelemiš, Mijomir
AU  - Antoniadis, Antonis
PY  - 2002
UR  - http://intor.torlakinstitut.com/handle/123456789/146
AB  - Crimean-Congo hemorrhagic fever virus (C-CHFV) strains were isolated from a fatal case and the attending physician in Kosovo, Yugoslavia. Early, rapid diagnosis of the disease was achieved by reverse transcription-polymerase chain reaction. The physician was successfully treated with oral ribavirin. These cases yielded the first genetically studied C-CHFV human isolates in the Balkans.
PB  - Centers for Disease Control and Prevention (CDC)
T2  - Emerging Infectious Diseases
T1  - Genetic detection and isolation of Crimean-Congo hemorrhagic fever virus, Kosovo, Yugoslavia
EP  - 854
IS  - 8
SP  - 852
VL  - 8
DO  - 10.3201/eid0808.010448
ER  - 

@article{
author = "Papa, Anna and Božović, Bojana and Pavlidou, V. and Papadimitriou, E. and Pelemiš, Mijomir and Antoniadis, Antonis",
year = "2002",
abstract = "Crimean-Congo hemorrhagic fever virus (C-CHFV) strains were isolated from a fatal case and the attending physician in Kosovo, Yugoslavia. Early, rapid diagnosis of the disease was achieved by reverse transcription-polymerase chain reaction. The physician was successfully treated with oral ribavirin. These cases yielded the first genetically studied C-CHFV human isolates in the Balkans.",
publisher = "Centers for Disease Control and Prevention (CDC)",
journal = "Emerging Infectious Diseases",
title = "Genetic detection and isolation of Crimean-Congo hemorrhagic fever virus, Kosovo, Yugoslavia",
pages = "854-852",
number = "8",
volume = "8",
doi = "10.3201/eid0808.010448"
}

Papa, A., Božović, B., Pavlidou, V., Papadimitriou, E., Pelemiš, M.,& Antoniadis, A.. (2002). Genetic detection and isolation of Crimean-Congo hemorrhagic fever virus, Kosovo, Yugoslavia. in Emerging Infectious Diseases
Centers for Disease Control and Prevention (CDC)., 8(8), 852-854.
https://doi.org/10.3201/eid0808.010448

Papa A, Božović B, Pavlidou V, Papadimitriou E, Pelemiš M, Antoniadis A. Genetic detection and isolation of Crimean-Congo hemorrhagic fever virus, Kosovo, Yugoslavia. in Emerging Infectious Diseases. 2002;8(8):852-854.
doi:10.3201/eid0808.010448 .

Papa, Anna, Božović, Bojana, Pavlidou, V., Papadimitriou, E., Pelemiš, Mijomir, Antoniadis, Antonis, "Genetic detection and isolation of Crimean-Congo hemorrhagic fever virus, Kosovo, Yugoslavia" in Emerging Infectious Diseases, 8, no. 8 (2002):852-854,
https://doi.org/10.3201/eid0808.010448 . .

TY  - JOUR
AU  - Đokić, Milomir
AU  - Bojić, Ivanko
AU  - Mikić, Dragan
AU  - Begović, Vesna
AU  - Božović, Bojana
AU  - Ćurčić, Petar
AU  - Rajić-Dimitrijević, Radmila
AU  - Drmanić, Sanja
PY  - 2000
UR  - http://intor.torlakinstitut.com/handle/123456789/123
AB  - Crimean-Congo hemorrhagic fever was for the first time recognized in Yugoslavia in 1971. In this paper were presented clinical and laboratory findings of a patient infected with Crimean-Congo hemorrhagic fever in Kosovo in 1999. The disease was manifested with fever, headache, vomiting, myalgia, abdominal pain, pharyngitis, conjunctival injection, diarrhoea, hypotension, gingival bleeding, skin hemorrhages, hematuria, hepatomegaly, splenomegaly, jaudice, thrombocytopenia, prolonged prothrombin and partial thromboplastin time, high serum fibrinogen degradation product, leukocytosis, mild anemia, elevated levels of bilirubin and serum aminotransferases. Diagnosis was set clinically, epidemiologically and supported by serological tests. Supportive management of hypotension, multi-organ failure, coagulation disturbances the patient was of the utmost in the treatment together with the isolation and prophylactic measures.
AB  - Krimska-kongo hemoragijska groznica prepoznata je prvi put u Jugoslaviji 1971. godine. Članak prikazuje kliničke i laboratorijske karakteristike kod bolesnika sa krimskom-kongo hemoragijskom groznicom inficiranog tokom boravka na Kosovu 1999. godine. Bolest se manifestovala febrilnošću, glavoboljom, povraćanjem, bolovima u mišićima, bolom u trbuhu, upalom ždrela, konjunktivnom injekcijom, prolivom, hipotenzijom, krvarenjem iz desni, krvarenjima na koži, hematurijom, uvećanjem jetre i slezine, žuticom, smanjenjem broja trombocita, produženim trombinskim i parcijalnim tromboplastinskim vremenom, povećanjem degradacionih produkata fibrinogena, leukocitozom, blažom anemijom, povišenjem serumskih vrednosti bilirubina i aminotransferaza. Dijagnoza je postavljena klinički, epidemiološki, a podržana serološkim testovima. U terapiji je najvažnije bilo suzbijanje hipotenzije, multiorganskih oštećenja, poremaćaja koagulacije uz izolaciju i primenu profilaktičkih mera.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - Crimean-Congo hemorrhagic fever
T1  - Krimska-kongo hemoragijska groznica
EP  - 471
IS  - 4
SP  - 467
VL  - 57
UR  - https://hdl.handle.net/21.15107/rcub_intor_123
ER  - 

@article{
author = "Đokić, Milomir and Bojić, Ivanko and Mikić, Dragan and Begović, Vesna and Božović, Bojana and Ćurčić, Petar and Rajić-Dimitrijević, Radmila and Drmanić, Sanja",
year = "2000",
abstract = "Crimean-Congo hemorrhagic fever was for the first time recognized in Yugoslavia in 1971. In this paper were presented clinical and laboratory findings of a patient infected with Crimean-Congo hemorrhagic fever in Kosovo in 1999. The disease was manifested with fever, headache, vomiting, myalgia, abdominal pain, pharyngitis, conjunctival injection, diarrhoea, hypotension, gingival bleeding, skin hemorrhages, hematuria, hepatomegaly, splenomegaly, jaudice, thrombocytopenia, prolonged prothrombin and partial thromboplastin time, high serum fibrinogen degradation product, leukocytosis, mild anemia, elevated levels of bilirubin and serum aminotransferases. Diagnosis was set clinically, epidemiologically and supported by serological tests. Supportive management of hypotension, multi-organ failure, coagulation disturbances the patient was of the utmost in the treatment together with the isolation and prophylactic measures., Krimska-kongo hemoragijska groznica prepoznata je prvi put u Jugoslaviji 1971. godine. Članak prikazuje kliničke i laboratorijske karakteristike kod bolesnika sa krimskom-kongo hemoragijskom groznicom inficiranog tokom boravka na Kosovu 1999. godine. Bolest se manifestovala febrilnošću, glavoboljom, povraćanjem, bolovima u mišićima, bolom u trbuhu, upalom ždrela, konjunktivnom injekcijom, prolivom, hipotenzijom, krvarenjem iz desni, krvarenjima na koži, hematurijom, uvećanjem jetre i slezine, žuticom, smanjenjem broja trombocita, produženim trombinskim i parcijalnim tromboplastinskim vremenom, povećanjem degradacionih produkata fibrinogena, leukocitozom, blažom anemijom, povišenjem serumskih vrednosti bilirubina i aminotransferaza. Dijagnoza je postavljena klinički, epidemiološki, a podržana serološkim testovima. U terapiji je najvažnije bilo suzbijanje hipotenzije, multiorganskih oštećenja, poremaćaja koagulacije uz izolaciju i primenu profilaktičkih mera.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "Crimean-Congo hemorrhagic fever, Krimska-kongo hemoragijska groznica",
pages = "471-467",
number = "4",
volume = "57",
url = "https://hdl.handle.net/21.15107/rcub_intor_123"
}

Đokić, M., Bojić, I., Mikić, D., Begović, V., Božović, B., Ćurčić, P., Rajić-Dimitrijević, R.,& Drmanić, S.. (2000). Crimean-Congo hemorrhagic fever. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 57(4), 467-471.
https://hdl.handle.net/21.15107/rcub_intor_123

Đokić M, Bojić I, Mikić D, Begović V, Božović B, Ćurčić P, Rajić-Dimitrijević R, Drmanić S. Crimean-Congo hemorrhagic fever. in Vojnosanitetski pregled. 2000;57(4):467-471.
https://hdl.handle.net/21.15107/rcub_intor_123 .

Đokić, Milomir, Bojić, Ivanko, Mikić, Dragan, Begović, Vesna, Božović, Bojana, Ćurčić, Petar, Rajić-Dimitrijević, Radmila, Drmanić, Sanja, "Crimean-Congo hemorrhagic fever" in Vojnosanitetski pregled, 57, no. 4 (2000):467-471,
https://hdl.handle.net/21.15107/rcub_intor_123 .