TY  - JOUR
AU  - Živanović, Mirjana
AU  - Atanasković-Marković, Marina
AU  - Međo, Biljana
AU  - Gavrović-Jankulović, Marija
AU  - Smiljanić, Katarina
AU  - Tmušić, Vladimir
AU  - Đurić, Vojislav
PY  - 2017
UR  - http://intor.torlakinstitut.com/handle/123456789/785
AB  - IgE-mediated food allergy affects 6-8% of children. Our study aimed to define the correlations between the results obtained with skin prick tests (SPTs) using commercial extracts and fresh foods, and the correlations between these result and those obtained with specific IgE (sIgE) and/or challenge. Children aged from 2 months to 6 years were recruited prospectively. Overall 571 children were positive to one food. In all children we performed SPT using commercial extracts of suspected food and fresh foods and sIgE. If SPT and sIgE test results did not correspond to the history, we performed open oral food challenge. Sensitivity of SPT with commercial extracts for all tested food was poor (3-35%), while sensitivity of fresh food skin prick tests (FFSPT) was excellent (50-100%), and showed correlation with open oral food challenge (p lt 0.001). Our results suggest that fresh food extracts are more effective in detecting sensitization and with levels of sIgE greater than class 3 could predict clinical reactivity, without the need for potentially hazardous food challenges.
PB  - Iranian Scientific Society Medical Entomology, Tehran
T2  - Iranian Journal of Allergy Asthma and Immunology
T1  - Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up
EP  - 132
IS  - 2
SP  - 127
VL  - 16
UR  - https://hdl.handle.net/21.15107/rcub_intor_785
ER  - 

@article{
author = "Živanović, Mirjana and Atanasković-Marković, Marina and Međo, Biljana and Gavrović-Jankulović, Marija and Smiljanić, Katarina and Tmušić, Vladimir and Đurić, Vojislav",
year = "2017",
abstract = "IgE-mediated food allergy affects 6-8% of children. Our study aimed to define the correlations between the results obtained with skin prick tests (SPTs) using commercial extracts and fresh foods, and the correlations between these result and those obtained with specific IgE (sIgE) and/or challenge. Children aged from 2 months to 6 years were recruited prospectively. Overall 571 children were positive to one food. In all children we performed SPT using commercial extracts of suspected food and fresh foods and sIgE. If SPT and sIgE test results did not correspond to the history, we performed open oral food challenge. Sensitivity of SPT with commercial extracts for all tested food was poor (3-35%), while sensitivity of fresh food skin prick tests (FFSPT) was excellent (50-100%), and showed correlation with open oral food challenge (p lt 0.001). Our results suggest that fresh food extracts are more effective in detecting sensitization and with levels of sIgE greater than class 3 could predict clinical reactivity, without the need for potentially hazardous food challenges.",
publisher = "Iranian Scientific Society Medical Entomology, Tehran",
journal = "Iranian Journal of Allergy Asthma and Immunology",
title = "Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up",
pages = "132-127",
number = "2",
volume = "16",
url = "https://hdl.handle.net/21.15107/rcub_intor_785"
}

Živanović, M., Atanasković-Marković, M., Međo, B., Gavrović-Jankulović, M., Smiljanić, K., Tmušić, V.,& Đurić, V.. (2017). Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up. in Iranian Journal of Allergy Asthma and Immunology
Iranian Scientific Society Medical Entomology, Tehran., 16(2), 127-132.
https://hdl.handle.net/21.15107/rcub_intor_785

Živanović M, Atanasković-Marković M, Međo B, Gavrović-Jankulović M, Smiljanić K, Tmušić V, Đurić V. Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up. in Iranian Journal of Allergy Asthma and Immunology. 2017;16(2):127-132.
https://hdl.handle.net/21.15107/rcub_intor_785 .

Živanović, Mirjana, Atanasković-Marković, Marina, Međo, Biljana, Gavrović-Jankulović, Marija, Smiljanić, Katarina, Tmušić, Vladimir, Đurić, Vojislav, "Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge: Our Five Years Experience in Food Allergy Work-up" in Iranian Journal of Allergy Asthma and Immunology, 16, no. 2 (2017):127-132,
https://hdl.handle.net/21.15107/rcub_intor_785 .

TY  - JOUR
AU  - Tomić-Spirić, Vesna
AU  - Dizdarević, Denisa
AU  - Janković, Slavenka
AU  - Burazer, Lidija
AU  - Barac, Aleksandra
AU  - Bolpacić, Jasna
AU  - Đurić, Vojislav
AU  - Perić-Popadić, Aleksandra
AU  - Aleksić, Aleksandra
AU  - Bogić, Mirjana
PY  - 2016
UR  - http://intor.torlakinstitut.com/handle/123456789/474
AB  - Sublingual allergen immunotherapy (SLIT) is considered to be safer and more convenient than subcutaneus immunotherapy. SLIT trials with house dust mites involving patients with allergic rhinitis (AR) and asthma reported discordant results. The aim of the study was to investigate the clinical efficacy and safety of SLIT with Dermatophagoides pteronyssinus (D.pt) extract produced in Serbia and patient's satisfaction through open-label trial. Adult patients with allergic rhinitis were randomized into two groups: one received drugs and SLIT, while other received only drugs. Symptom score (SS), medication score (MS) and cumulative score (CS), skin prick tests (SPT) and serum level of D. pt specific IgE were assessed. One year after, the patients were re-evaluated. In total, 61 patients were enrolled in the study, but 52 of them were analyzed at the end of the year. CS (29.3%, p lt  0.001) and MS (54.3%, p lt  0.05) reduced significantly in the SLIT group. There was a significant improvement of MS and CS in the SLIT compared to control group (p lt  0.001 and p lt  0.05 respectively). There was no significant improvement of SS as well as specific slgE. Patients in the SLIT group were more satisfied with treatment (p lt  0.001). The incidence of mild adverse reaction was 38.4%. Specific lgG was not done. One year SLIT with D. pt extract was clinically efficient treatment in AR patients.
PB  - Tehran Univ Medical Sciences, Tehran
T2  - Iranian Journal of Allergy, Asthma and Immunology
T1  - Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study
EP  - 121
IS  - 2
SP  - 112
VL  - 15
UR  - https://hdl.handle.net/21.15107/rcub_intor_474
ER  - 

@article{
author = "Tomić-Spirić, Vesna and Dizdarević, Denisa and Janković, Slavenka and Burazer, Lidija and Barac, Aleksandra and Bolpacić, Jasna and Đurić, Vojislav and Perić-Popadić, Aleksandra and Aleksić, Aleksandra and Bogić, Mirjana",
year = "2016",
abstract = "Sublingual allergen immunotherapy (SLIT) is considered to be safer and more convenient than subcutaneus immunotherapy. SLIT trials with house dust mites involving patients with allergic rhinitis (AR) and asthma reported discordant results. The aim of the study was to investigate the clinical efficacy and safety of SLIT with Dermatophagoides pteronyssinus (D.pt) extract produced in Serbia and patient's satisfaction through open-label trial. Adult patients with allergic rhinitis were randomized into two groups: one received drugs and SLIT, while other received only drugs. Symptom score (SS), medication score (MS) and cumulative score (CS), skin prick tests (SPT) and serum level of D. pt specific IgE were assessed. One year after, the patients were re-evaluated. In total, 61 patients were enrolled in the study, but 52 of them were analyzed at the end of the year. CS (29.3%, p lt  0.001) and MS (54.3%, p lt  0.05) reduced significantly in the SLIT group. There was a significant improvement of MS and CS in the SLIT compared to control group (p lt  0.001 and p lt  0.05 respectively). There was no significant improvement of SS as well as specific slgE. Patients in the SLIT group were more satisfied with treatment (p lt  0.001). The incidence of mild adverse reaction was 38.4%. Specific lgG was not done. One year SLIT with D. pt extract was clinically efficient treatment in AR patients.",
publisher = "Tehran Univ Medical Sciences, Tehran",
journal = "Iranian Journal of Allergy, Asthma and Immunology",
title = "Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study",
pages = "121-112",
number = "2",
volume = "15",
url = "https://hdl.handle.net/21.15107/rcub_intor_474"
}

Tomić-Spirić, V., Dizdarević, D., Janković, S., Burazer, L., Barac, A., Bolpacić, J., Đurić, V., Perić-Popadić, A., Aleksić, A.,& Bogić, M.. (2016). Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study. in Iranian Journal of Allergy, Asthma and Immunology
Tehran Univ Medical Sciences, Tehran., 15(2), 112-121.
https://hdl.handle.net/21.15107/rcub_intor_474

Tomić-Spirić V, Dizdarević D, Janković S, Burazer L, Barac A, Bolpacić J, Đurić V, Perić-Popadić A, Aleksić A, Bogić M. Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study. in Iranian Journal of Allergy, Asthma and Immunology. 2016;15(2):112-121.
https://hdl.handle.net/21.15107/rcub_intor_474 .

Tomić-Spirić, Vesna, Dizdarević, Denisa, Janković, Slavenka, Burazer, Lidija, Barac, Aleksandra, Bolpacić, Jasna, Đurić, Vojislav, Perić-Popadić, Aleksandra, Aleksić, Aleksandra, Bogić, Mirjana, "Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study" in Iranian Journal of Allergy, Asthma and Immunology, 15, no. 2 (2016):112-121,
https://hdl.handle.net/21.15107/rcub_intor_474 .