TY  - JOUR
AU  - Stanojević, Maja
AU  - Nikolić, V.
AU  - Stajković, Novica
AU  - Stamenković, Gorana
AU  - Božović, Bojana
AU  - Čekanac, Radovan
AU  - Marušić, Predrag
AU  - Gligić, Ana
PY  - 2015
UR  - http://intor.torlakinstitut.com/handle/123456789/439
AB  - Hantaviruses are endemic in the Balkans, particularly in Serbia, where sporadic cases and/or outbreaks of hantaviral human disease have been reported repeatedly, and evidenced serologically. Here, we present genetic detection of Dobrava-Belgrade virus (DOBV) hantaviral sequences in wild rodents trapped in central Serbia. All the animals were pre-screened serologically by indirect immunofluorescence (IF) test and only those with a positive finding of hantaviral antigens were further tested by polymerase chain reaction. Of the total of 104 trapped animals, 20 were found to be IF positive and of those three were positive for hantaviral RNA: one Microtus arvalis for Tula virus, and one each of Apodemus agrarius and Glis glis for DOBV. Phylogenetic analysis of the obtained sequences implies putative DOBV spillover infection of A. agrarius and G. glis from Apodemus flavicollis. However, future investigations should help to identify the most common natural host and geographical distribution of DOBV in its reservoir hosts in Serbia.
PB  - Cambridge Univ Press, New York
T2  - Epidemiology and Infection
T1  - Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia
EP  - 404
IS  - 2
SP  - 400
VL  - 143
DO  - 10.1017/S0950268814001010
ER  - 

@article{
author = "Stanojević, Maja and Nikolić, V. and Stajković, Novica and Stamenković, Gorana and Božović, Bojana and Čekanac, Radovan and Marušić, Predrag and Gligić, Ana",
year = "2015",
abstract = "Hantaviruses are endemic in the Balkans, particularly in Serbia, where sporadic cases and/or outbreaks of hantaviral human disease have been reported repeatedly, and evidenced serologically. Here, we present genetic detection of Dobrava-Belgrade virus (DOBV) hantaviral sequences in wild rodents trapped in central Serbia. All the animals were pre-screened serologically by indirect immunofluorescence (IF) test and only those with a positive finding of hantaviral antigens were further tested by polymerase chain reaction. Of the total of 104 trapped animals, 20 were found to be IF positive and of those three were positive for hantaviral RNA: one Microtus arvalis for Tula virus, and one each of Apodemus agrarius and Glis glis for DOBV. Phylogenetic analysis of the obtained sequences implies putative DOBV spillover infection of A. agrarius and G. glis from Apodemus flavicollis. However, future investigations should help to identify the most common natural host and geographical distribution of DOBV in its reservoir hosts in Serbia.",
publisher = "Cambridge Univ Press, New York",
journal = "Epidemiology and Infection",
title = "Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia",
pages = "404-400",
number = "2",
volume = "143",
doi = "10.1017/S0950268814001010"
}

Stanojević, M., Nikolić, V., Stajković, N., Stamenković, G., Božović, B., Čekanac, R., Marušić, P.,& Gligić, A.. (2015). Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia. in Epidemiology and Infection
Cambridge Univ Press, New York., 143(2), 400-404.
https://doi.org/10.1017/S0950268814001010

Stanojević M, Nikolić V, Stajković N, Stamenković G, Božović B, Čekanac R, Marušić P, Gligić A. Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia. in Epidemiology and Infection. 2015;143(2):400-404.
doi:10.1017/S0950268814001010 .

Stanojević, Maja, Nikolić, V., Stajković, Novica, Stamenković, Gorana, Božović, Bojana, Čekanac, Radovan, Marušić, Predrag, Gligić, Ana, "Genetic detection of Dobrava-Belgrade hantavirus in the edible dormouse (Glis glis) in central Serbia" in Epidemiology and Infection, 143, no. 2 (2015):400-404,
https://doi.org/10.1017/S0950268814001010 . .

TY  - JOUR
AU  - Bogdanović, R.
AU  - Gligić, Ana
AU  - Nikolić, V.
AU  - Ognjanović, M.
AU  - Marković, M.
AU  - Sarjanović, L.
PY  - 1994
UR  - http://intor.torlakinstitut.com/handle/123456789/55
AB  - During an outbreak of haemorrhagic fever with renal syndrome (HFRS) in 1989, five children (3 girls, 2 boys, aged 6.8-16 years) with a severe form of the disease were treated; four of these were followed for 22-28 months. The main clinical features in all five patients were: fever, headache, myalgia, abdominal and back pain and vomiting; haemorrhagic syndrome was present in four children. Renal syndrome presented with severe acute renal failure in all five patients. All patients recovered. Serological confirmation by an indirect immunofluorescence assay, by enzyme immunoassay for IgM antibodies and by plaque reduction neutralization test showed infection by Belgrade virus in three and by Hantaan virus in two patients. It was not possible to differentiate these two serogroups on the basis of clinical features. This study provides futher information on the circulation of different hantaviruses causing severe HFRS in Serbia.
PB  - Springer-Verlag
T2  - Pediatric Nephrology
T1  - Belgrade and Hantaan hantaviruses - the causative agents of severe haemorrhagic fever with renal syndrome in children in Serbia
EP  - 303
IS  - 3
SP  - 299
VL  - 8
DO  - 10.1007/BF00866341
ER  - 

@article{
author = "Bogdanović, R. and Gligić, Ana and Nikolić, V. and Ognjanović, M. and Marković, M. and Sarjanović, L.",
year = "1994",
abstract = "During an outbreak of haemorrhagic fever with renal syndrome (HFRS) in 1989, five children (3 girls, 2 boys, aged 6.8-16 years) with a severe form of the disease were treated; four of these were followed for 22-28 months. The main clinical features in all five patients were: fever, headache, myalgia, abdominal and back pain and vomiting; haemorrhagic syndrome was present in four children. Renal syndrome presented with severe acute renal failure in all five patients. All patients recovered. Serological confirmation by an indirect immunofluorescence assay, by enzyme immunoassay for IgM antibodies and by plaque reduction neutralization test showed infection by Belgrade virus in three and by Hantaan virus in two patients. It was not possible to differentiate these two serogroups on the basis of clinical features. This study provides futher information on the circulation of different hantaviruses causing severe HFRS in Serbia.",
publisher = "Springer-Verlag",
journal = "Pediatric Nephrology",
title = "Belgrade and Hantaan hantaviruses - the causative agents of severe haemorrhagic fever with renal syndrome in children in Serbia",
pages = "303-299",
number = "3",
volume = "8",
doi = "10.1007/BF00866341"
}

Bogdanović, R., Gligić, A., Nikolić, V., Ognjanović, M., Marković, M.,& Sarjanović, L.. (1994). Belgrade and Hantaan hantaviruses - the causative agents of severe haemorrhagic fever with renal syndrome in children in Serbia. in Pediatric Nephrology
Springer-Verlag., 8(3), 299-303.
https://doi.org/10.1007/BF00866341

Bogdanović R, Gligić A, Nikolić V, Ognjanović M, Marković M, Sarjanović L. Belgrade and Hantaan hantaviruses - the causative agents of severe haemorrhagic fever with renal syndrome in children in Serbia. in Pediatric Nephrology. 1994;8(3):299-303.
doi:10.1007/BF00866341 .

Bogdanović, R., Gligić, Ana, Nikolić, V., Ognjanović, M., Marković, M., Sarjanović, L., "Belgrade and Hantaan hantaviruses - the causative agents of severe haemorrhagic fever with renal syndrome in children in Serbia" in Pediatric Nephrology, 8, no. 3 (1994):299-303,
https://doi.org/10.1007/BF00866341 . .