TY  - JOUR
AU  - Tomić-Spirić, Vesna
AU  - Dizdarević, Denisa
AU  - Janković, Slavenka
AU  - Burazer, Lidija
AU  - Barac, Aleksandra
AU  - Bolpacić, Jasna
AU  - Đurić, Vojislav
AU  - Perić-Popadić, Aleksandra
AU  - Aleksić, Aleksandra
AU  - Bogić, Mirjana
PY  - 2016
UR  - http://intor.torlakinstitut.com/handle/123456789/474
AB  - Sublingual allergen immunotherapy (SLIT) is considered to be safer and more convenient than subcutaneus immunotherapy. SLIT trials with house dust mites involving patients with allergic rhinitis (AR) and asthma reported discordant results. The aim of the study was to investigate the clinical efficacy and safety of SLIT with Dermatophagoides pteronyssinus (D.pt) extract produced in Serbia and patient's satisfaction through open-label trial. Adult patients with allergic rhinitis were randomized into two groups: one received drugs and SLIT, while other received only drugs. Symptom score (SS), medication score (MS) and cumulative score (CS), skin prick tests (SPT) and serum level of D. pt specific IgE were assessed. One year after, the patients were re-evaluated. In total, 61 patients were enrolled in the study, but 52 of them were analyzed at the end of the year. CS (29.3%, p lt  0.001) and MS (54.3%, p lt  0.05) reduced significantly in the SLIT group. There was a significant improvement of MS and CS in the SLIT compared to control group (p lt  0.001 and p lt  0.05 respectively). There was no significant improvement of SS as well as specific slgE. Patients in the SLIT group were more satisfied with treatment (p lt  0.001). The incidence of mild adverse reaction was 38.4%. Specific lgG was not done. One year SLIT with D. pt extract was clinically efficient treatment in AR patients.
PB  - Tehran Univ Medical Sciences, Tehran
T2  - Iranian Journal of Allergy, Asthma and Immunology
T1  - Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study
EP  - 121
IS  - 2
SP  - 112
VL  - 15
UR  - https://hdl.handle.net/21.15107/rcub_intor_474
ER  - 

@article{
author = "Tomić-Spirić, Vesna and Dizdarević, Denisa and Janković, Slavenka and Burazer, Lidija and Barac, Aleksandra and Bolpacić, Jasna and Đurić, Vojislav and Perić-Popadić, Aleksandra and Aleksić, Aleksandra and Bogić, Mirjana",
year = "2016",
abstract = "Sublingual allergen immunotherapy (SLIT) is considered to be safer and more convenient than subcutaneus immunotherapy. SLIT trials with house dust mites involving patients with allergic rhinitis (AR) and asthma reported discordant results. The aim of the study was to investigate the clinical efficacy and safety of SLIT with Dermatophagoides pteronyssinus (D.pt) extract produced in Serbia and patient's satisfaction through open-label trial. Adult patients with allergic rhinitis were randomized into two groups: one received drugs and SLIT, while other received only drugs. Symptom score (SS), medication score (MS) and cumulative score (CS), skin prick tests (SPT) and serum level of D. pt specific IgE were assessed. One year after, the patients were re-evaluated. In total, 61 patients were enrolled in the study, but 52 of them were analyzed at the end of the year. CS (29.3%, p lt  0.001) and MS (54.3%, p lt  0.05) reduced significantly in the SLIT group. There was a significant improvement of MS and CS in the SLIT compared to control group (p lt  0.001 and p lt  0.05 respectively). There was no significant improvement of SS as well as specific slgE. Patients in the SLIT group were more satisfied with treatment (p lt  0.001). The incidence of mild adverse reaction was 38.4%. Specific lgG was not done. One year SLIT with D. pt extract was clinically efficient treatment in AR patients.",
publisher = "Tehran Univ Medical Sciences, Tehran",
journal = "Iranian Journal of Allergy, Asthma and Immunology",
title = "Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study",
pages = "121-112",
number = "2",
volume = "15",
url = "https://hdl.handle.net/21.15107/rcub_intor_474"
}

Tomić-Spirić, V., Dizdarević, D., Janković, S., Burazer, L., Barac, A., Bolpacić, J., Đurić, V., Perić-Popadić, A., Aleksić, A.,& Bogić, M.. (2016). Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study. in Iranian Journal of Allergy, Asthma and Immunology
Tehran Univ Medical Sciences, Tehran., 15(2), 112-121.
https://hdl.handle.net/21.15107/rcub_intor_474

Tomić-Spirić V, Dizdarević D, Janković S, Burazer L, Barac A, Bolpacić J, Đurić V, Perić-Popadić A, Aleksić A, Bogić M. Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study. in Iranian Journal of Allergy, Asthma and Immunology. 2016;15(2):112-121.
https://hdl.handle.net/21.15107/rcub_intor_474 .

Tomić-Spirić, Vesna, Dizdarević, Denisa, Janković, Slavenka, Burazer, Lidija, Barac, Aleksandra, Bolpacić, Jasna, Đurić, Vojislav, Perić-Popadić, Aleksandra, Aleksić, Aleksandra, Bogić, Mirjana, "Efficacy of Sublingual Immunotherapy with Dermatophagoides Pteronyssinus: A Real-life Study" in Iranian Journal of Allergy, Asthma and Immunology, 15, no. 2 (2016):112-121,
https://hdl.handle.net/21.15107/rcub_intor_474 .

TY  - JOUR
AU  - Bogić, Mirjana
AU  - Rašković, S.
AU  - Sojić, J.
AU  - Boricić, I.
AU  - Ješić, R.
AU  - Burazer, Lidija
AU  - Spirić, V.T.
AU  - Popadić, A.P.
AU  - Đurić, V.
AU  - Celeketić, D.
PY  - 2004
UR  - http://intor.torlakinstitut.com/handle/123456789/174
AB  - Drug hypersensitivity syndrome is a severe form of hypersensitivity to the antiepileptic agent carbamazepine, particularly in presence of visceral and hematological manifestations that must be evidenced and treated in time. Two cases of female patients with carbamazepine-induced hypersensitivity syndrome are reported. Both patients had prominent general complaints (febricity, weakness). The first patient had leukopenia, lymphadenopathy and rash, while the other one had urticaria, angioedema and hepatitis after administration of carbamazepine. Hypersensitivity reactions induced by antiepileptics widely applied in the practice may be severe and life-threatening if blood elements are involved via the immune or nonimmune mechanisms and if they result in hepatitis.
PB  - Dustri-Verlag Dr Karl Feistle, Deisenhofen-Muenchen
T2  - Allergologie
T1  - Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases
EP  - 472
IS  - 11
SP  - 468
VL  - 27
DO  - 10.5414/ALP27468
ER  - 

@article{
author = "Bogić, Mirjana and Rašković, S. and Sojić, J. and Boricić, I. and Ješić, R. and Burazer, Lidija and Spirić, V.T. and Popadić, A.P. and Đurić, V. and Celeketić, D.",
year = "2004",
abstract = "Drug hypersensitivity syndrome is a severe form of hypersensitivity to the antiepileptic agent carbamazepine, particularly in presence of visceral and hematological manifestations that must be evidenced and treated in time. Two cases of female patients with carbamazepine-induced hypersensitivity syndrome are reported. Both patients had prominent general complaints (febricity, weakness). The first patient had leukopenia, lymphadenopathy and rash, while the other one had urticaria, angioedema and hepatitis after administration of carbamazepine. Hypersensitivity reactions induced by antiepileptics widely applied in the practice may be severe and life-threatening if blood elements are involved via the immune or nonimmune mechanisms and if they result in hepatitis.",
publisher = "Dustri-Verlag Dr Karl Feistle, Deisenhofen-Muenchen",
journal = "Allergologie",
title = "Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases",
pages = "472-468",
number = "11",
volume = "27",
doi = "10.5414/ALP27468"
}

Bogić, M., Rašković, S., Sojić, J., Boricić, I., Ješić, R., Burazer, L., Spirić, V.T., Popadić, A.P., Đurić, V.,& Celeketić, D.. (2004). Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases. in Allergologie
Dustri-Verlag Dr Karl Feistle, Deisenhofen-Muenchen., 27(11), 468-472.
https://doi.org/10.5414/ALP27468

Bogić M, Rašković S, Sojić J, Boricić I, Ješić R, Burazer L, Spirić V, Popadić A, Đurić V, Celeketić D. Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases. in Allergologie. 2004;27(11):468-472.
doi:10.5414/ALP27468 .

Bogić, Mirjana, Rašković, S., Sojić, J., Boricić, I., Ješić, R., Burazer, Lidija, Spirić, V.T., Popadić, A.P., Đurić, V., Celeketić, D., "Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases" in Allergologie, 27, no. 11 (2004):468-472,
https://doi.org/10.5414/ALP27468 . .