TY  - JOUR
AU  - Dimitrijević, Ljiljana
AU  - Stojanović, M.
AU  - Cirić, B.
AU  - Radulović, M.
AU  - Stojanović, R.
AU  - Popović, Zoran
AU  - Inić-Kanada, Aleksandra
AU  - Živković, Irena
PY  - 2004
UR  - http://intor.torlakinstitut.com/handle/123456789/178
AB  - In this paper we report data regarding the IgM Y7 cross-reactive idiotope (CRIo) obtained by analysis of: 1) its V-gene subgroup dependance, 2) the frequency of its expression on human monoclonal IgMs and IgM molecules from normal and pathological sera. Furthermore, comparison of epitopic repertoire and nature of binding of human monoclonal IgMs expressing Y7 CRIo was performed to confirm the natural antibody properties of these molecules. IgM isolated from sera of patient DJ (IgM DJ) which expresses the Y7 idiotope has been classified to V(H)3/V(L)2 subgroup. From ten IgMs tested only IgM from patient RD (IgM RD) has been shown to express Y7 idiotope. Y7(+) human IgMs bound to ssDNA, lactic acid bacteria, mouse laminin, porcine thyroglobulin and mouse IgG. Higher percentage of the expression of Y7 CRIo was detected in the sera of patients suffering from autoimmune diseases such as lupus, rheumatoid arthritis and psoriasis vulgaris as well as in patients suffering from chronic infections of the lower urinary tract. Antigen binding repertoire and properties of Y7(+) monoclonal IgM, frequency of Y7 expression on monoclonal IgMs and its concentration in normal and pathological sera indicate the important biological role of this CRIo within the immune system.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Immunological Investigations
T1  - Expression of Y7 cross-reactive idiotope on human IgM molecules
EP  - 14
IS  - 1
SP  - 1
VL  - 33
DO  - 10.1081/IMM-120027680
ER  - 

@article{
author = "Dimitrijević, Ljiljana and Stojanović, M. and Cirić, B. and Radulović, M. and Stojanović, R. and Popović, Zoran and Inić-Kanada, Aleksandra and Živković, Irena",
year = "2004",
abstract = "In this paper we report data regarding the IgM Y7 cross-reactive idiotope (CRIo) obtained by analysis of: 1) its V-gene subgroup dependance, 2) the frequency of its expression on human monoclonal IgMs and IgM molecules from normal and pathological sera. Furthermore, comparison of epitopic repertoire and nature of binding of human monoclonal IgMs expressing Y7 CRIo was performed to confirm the natural antibody properties of these molecules. IgM isolated from sera of patient DJ (IgM DJ) which expresses the Y7 idiotope has been classified to V(H)3/V(L)2 subgroup. From ten IgMs tested only IgM from patient RD (IgM RD) has been shown to express Y7 idiotope. Y7(+) human IgMs bound to ssDNA, lactic acid bacteria, mouse laminin, porcine thyroglobulin and mouse IgG. Higher percentage of the expression of Y7 CRIo was detected in the sera of patients suffering from autoimmune diseases such as lupus, rheumatoid arthritis and psoriasis vulgaris as well as in patients suffering from chronic infections of the lower urinary tract. Antigen binding repertoire and properties of Y7(+) monoclonal IgM, frequency of Y7 expression on monoclonal IgMs and its concentration in normal and pathological sera indicate the important biological role of this CRIo within the immune system.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Immunological Investigations",
title = "Expression of Y7 cross-reactive idiotope on human IgM molecules",
pages = "14-1",
number = "1",
volume = "33",
doi = "10.1081/IMM-120027680"
}

Dimitrijević, L., Stojanović, M., Cirić, B., Radulović, M., Stojanović, R., Popović, Z., Inić-Kanada, A.,& Živković, I.. (2004). Expression of Y7 cross-reactive idiotope on human IgM molecules. in Immunological Investigations
Taylor & Francis Inc, Philadelphia., 33(1), 1-14.
https://doi.org/10.1081/IMM-120027680

Dimitrijević L, Stojanović M, Cirić B, Radulović M, Stojanović R, Popović Z, Inić-Kanada A, Živković I. Expression of Y7 cross-reactive idiotope on human IgM molecules. in Immunological Investigations. 2004;33(1):1-14.
doi:10.1081/IMM-120027680 .

Dimitrijević, Ljiljana, Stojanović, M., Cirić, B., Radulović, M., Stojanović, R., Popović, Zoran, Inić-Kanada, Aleksandra, Živković, Irena, "Expression of Y7 cross-reactive idiotope on human IgM molecules" in Immunological Investigations, 33, no. 1 (2004):1-14,
https://doi.org/10.1081/IMM-120027680 . .

TY  - JOUR
AU  - Diglisić, G.
AU  - Xiao, S.-Y.
AU  - Gligić, Ana
AU  - Obradović, M.
AU  - Stojanović, R.
AU  - Velimirović, D.
AU  - Lukac, V.
AU  - Rossi, C.A.
AU  - Le Duc, J.W.
PY  - 1994
UR  - http://intor.torlakinstitut.com/handle/123456789/57
AB  - An outbreak of severe hemorrhagic fever with renal syndrome (HFRS) occurred in 1988 in Pozarevac, Serbia, Yugoslavia. The disease was diagnosed in 4 children and I adult, and I of the children died. Rodents were captured from the same area and virus isolation attempted. A hantavirus, POZ-M1, was isolated from lung tissues of hantavirus antigen-positive Mus musculus. Serology and restriction enzyme digestion of polymerase chain reaction-amplified segments from this virus showed that it was a strain of Puumala (PUU) virus, the causative agent of nephropathia epidemica. While Clethrionomys glareolus is the major rodent host for PUU virus, these results suggest that M. musculus may also play an important role in harboring and transmitting PUU-like viruses. The serologic association of this virus with patients with severe HFRS reaffirms that PUU-like viruses may cause severe disease in addition to the generally mild form normally associated with nephropathia epidemica.
T2  - Journal of Infectious Diseases
T1  - Isolation of a puumala-like virus from mus musculus captured in yugoslavia and its association with severe hemorrhagic fever with renal syndrome
EP  - 207
IS  - 1
SP  - 204
VL  - 169
DO  - 10.1093/infdis/169.1.204
ER  - 

@article{
author = "Diglisić, G. and Xiao, S.-Y. and Gligić, Ana and Obradović, M. and Stojanović, R. and Velimirović, D. and Lukac, V. and Rossi, C.A. and Le Duc, J.W.",
year = "1994",
abstract = "An outbreak of severe hemorrhagic fever with renal syndrome (HFRS) occurred in 1988 in Pozarevac, Serbia, Yugoslavia. The disease was diagnosed in 4 children and I adult, and I of the children died. Rodents were captured from the same area and virus isolation attempted. A hantavirus, POZ-M1, was isolated from lung tissues of hantavirus antigen-positive Mus musculus. Serology and restriction enzyme digestion of polymerase chain reaction-amplified segments from this virus showed that it was a strain of Puumala (PUU) virus, the causative agent of nephropathia epidemica. While Clethrionomys glareolus is the major rodent host for PUU virus, these results suggest that M. musculus may also play an important role in harboring and transmitting PUU-like viruses. The serologic association of this virus with patients with severe HFRS reaffirms that PUU-like viruses may cause severe disease in addition to the generally mild form normally associated with nephropathia epidemica.",
journal = "Journal of Infectious Diseases",
title = "Isolation of a puumala-like virus from mus musculus captured in yugoslavia and its association with severe hemorrhagic fever with renal syndrome",
pages = "207-204",
number = "1",
volume = "169",
doi = "10.1093/infdis/169.1.204"
}

Diglisić, G., Xiao, S.-Y., Gligić, A., Obradović, M., Stojanović, R., Velimirović, D., Lukac, V., Rossi, C.A.,& Le Duc, J.W.. (1994). Isolation of a puumala-like virus from mus musculus captured in yugoslavia and its association with severe hemorrhagic fever with renal syndrome. in Journal of Infectious Diseases, 169(1), 204-207.
https://doi.org/10.1093/infdis/169.1.204

Diglisić G, Xiao S, Gligić A, Obradović M, Stojanović R, Velimirović D, Lukac V, Rossi C, Le Duc J. Isolation of a puumala-like virus from mus musculus captured in yugoslavia and its association with severe hemorrhagic fever with renal syndrome. in Journal of Infectious Diseases. 1994;169(1):204-207.
doi:10.1093/infdis/169.1.204 .

Diglisić, G., Xiao, S.-Y., Gligić, Ana, Obradović, M., Stojanović, R., Velimirović, D., Lukac, V., Rossi, C.A., Le Duc, J.W., "Isolation of a puumala-like virus from mus musculus captured in yugoslavia and its association with severe hemorrhagic fever with renal syndrome" in Journal of Infectious Diseases, 169, no. 1 (1994):204-207,
https://doi.org/10.1093/infdis/169.1.204 . .

TY  - JOUR
AU  - Gligić, Ana
AU  - Obradović, M.
AU  - Stojanović, R.
AU  - Vujošević, N.
AU  - Ovcarić, A.
AU  - Frusić, M.
AU  - Gibbs Jr.
AU  - Calisher, C.H.
AU  - Gajdusek, D.C.
PY  - 1989
UR  - http://intor.torlakinstitut.com/handle/123456789/31
AB  - An epidemic of hemorrhagic fever with renal syndrome (HFRS) occurred in Yugoslavia May-November 1986; all Republics and Provinces were involved. Serum samples were received from 260 of 267 persons with symptoms clinically compatible with a diagnosis of HFRS. Presumptive infection with a hantavirus was determined serologically for 161 of these. Many patients with serious clinical pictures, including severe renal insufficiency and shock, were hospitalized; 11 died. Indirect fluorescent antibody tests with antigens of 4 hantaviruses (Hantaan, Fojnica, Puumala, and the Vranica strain of Puumala virus) showed that  gt 1 serotype was circulating during this epidemic. Hantavirus antigens were detected in the lungs of 86 of 302 (28.5%) wild-caught small mammals.
T2  - American Journal of Tropical Medicine and Hygiene
T1  - Epidemic hemorrhagic fever with renal syndrome in Yugoslavia, 1986
EP  - 108
IS  - 1
SP  - 102
VL  - 41
DO  - 10.4269/ajtmh.1989.41.102
ER  - 

@article{
author = "Gligić, Ana and Obradović, M. and Stojanović, R. and Vujošević, N. and Ovcarić, A. and Frusić, M. and Gibbs Jr. and Calisher, C.H. and Gajdusek, D.C.",
year = "1989",
abstract = "An epidemic of hemorrhagic fever with renal syndrome (HFRS) occurred in Yugoslavia May-November 1986; all Republics and Provinces were involved. Serum samples were received from 260 of 267 persons with symptoms clinically compatible with a diagnosis of HFRS. Presumptive infection with a hantavirus was determined serologically for 161 of these. Many patients with serious clinical pictures, including severe renal insufficiency and shock, were hospitalized; 11 died. Indirect fluorescent antibody tests with antigens of 4 hantaviruses (Hantaan, Fojnica, Puumala, and the Vranica strain of Puumala virus) showed that  gt 1 serotype was circulating during this epidemic. Hantavirus antigens were detected in the lungs of 86 of 302 (28.5%) wild-caught small mammals.",
journal = "American Journal of Tropical Medicine and Hygiene",
title = "Epidemic hemorrhagic fever with renal syndrome in Yugoslavia, 1986",
pages = "108-102",
number = "1",
volume = "41",
doi = "10.4269/ajtmh.1989.41.102"
}

Gligić, A., Obradović, M., Stojanović, R., Vujošević, N., Ovcarić, A., Frusić, M., Gibbs Jr., Calisher, C.H.,& Gajdusek, D.C.. (1989). Epidemic hemorrhagic fever with renal syndrome in Yugoslavia, 1986. in American Journal of Tropical Medicine and Hygiene, 41(1), 102-108.
https://doi.org/10.4269/ajtmh.1989.41.102

Gligić A, Obradović M, Stojanović R, Vujošević N, Ovcarić A, Frusić M, Gibbs Jr., Calisher C, Gajdusek D. Epidemic hemorrhagic fever with renal syndrome in Yugoslavia, 1986. in American Journal of Tropical Medicine and Hygiene. 1989;41(1):102-108.
doi:10.4269/ajtmh.1989.41.102 .

Gligić, Ana, Obradović, M., Stojanović, R., Vujošević, N., Ovcarić, A., Frusić, M., Gibbs Jr., Calisher, C.H., Gajdusek, D.C., "Epidemic hemorrhagic fever with renal syndrome in Yugoslavia, 1986" in American Journal of Tropical Medicine and Hygiene, 41, no. 1 (1989):102-108,
https://doi.org/10.4269/ajtmh.1989.41.102 . .