Apostolov, K.

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  • Apostolov, K. (4)
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Author's Bibliography

Nature of the virus associated with endemic Balkan nephropathy

Riquelme, C.; Escors, D.; Ortego, J.; Sanchez, C.M.; Uzelac-Keserović, B.; Apostolov, K.; Enjuanes, L.

(Centers Disease Control & Prevention, Atlanta, 2002)

TY  - JOUR
AU  - Riquelme, C.
AU  - Escors, D.
AU  - Ortego, J.
AU  - Sanchez, C.M.
AU  - Uzelac-Keserović, B.
AU  - Apostolov, K.
AU  - Enjuanes, L.
PY  - 2002
UR  - http://intor.torlakinstitut.com/handle/123456789/147
PB  - Centers  Disease Control & Prevention, Atlanta
T2  - Emerging Infectious Diseases
T1  - Nature of the virus associated with endemic Balkan nephropathy
EP  - 870
IS  - 8
SP  - 869
VL  - 8
DO  - 10.3201/eid0808.020042
ER  - 
@article{
author = "Riquelme, C. and Escors, D. and Ortego, J. and Sanchez, C.M. and Uzelac-Keserović, B. and Apostolov, K. and Enjuanes, L.",
year = "2002",
publisher = "Centers  Disease Control & Prevention, Atlanta",
journal = "Emerging Infectious Diseases",
title = "Nature of the virus associated with endemic Balkan nephropathy",
pages = "870-869",
number = "8",
volume = "8",
doi = "10.3201/eid0808.020042"
}
Riquelme, C., Escors, D., Ortego, J., Sanchez, C.M., Uzelac-Keserović, B., Apostolov, K.,& Enjuanes, L.. (2002). Nature of the virus associated with endemic Balkan nephropathy. in Emerging Infectious Diseases
Centers  Disease Control & Prevention, Atlanta., 8(8), 869-870.
https://doi.org/10.3201/eid0808.020042
Riquelme C, Escors D, Ortego J, Sanchez C, Uzelac-Keserović B, Apostolov K, Enjuanes L. Nature of the virus associated with endemic Balkan nephropathy. in Emerging Infectious Diseases. 2002;8(8):869-870.
doi:10.3201/eid0808.020042 .
Riquelme, C., Escors, D., Ortego, J., Sanchez, C.M., Uzelac-Keserović, B., Apostolov, K., Enjuanes, L., "Nature of the virus associated with endemic Balkan nephropathy" in Emerging Infectious Diseases, 8, no. 8 (2002):869-870,
https://doi.org/10.3201/eid0808.020042 . .
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Virus isolation from the kidney, tumors and lymph nodes of patients with ben

Uzelac-Keserović, B.; Apostolov, K.

(Univerzitet u Nišu, Niš, 2002)

TY  - JOUR
AU  - Uzelac-Keserović, B.
AU  - Apostolov, K.
PY  - 2002
UR  - http://intor.torlakinstitut.com/handle/123456789/139
AB  - This paper is based on two recent publications (1,2), and one submitted for publication (submittted for publi-cation). There is an important correction. In the two previous publications in Nephron it was stated that the virus isolated from the kidneys, the tumors and meta-static lymph glands was classified as a coronavirus (1,2). Subsequent more detailed investigations revealed that the virus should not be identified as a coronavirus (submittted for publication). However, the evidence presented in this work suggests strongly that the newly isolated virus is involved in the ethyology of BEN. The new findings open the possibility of reassessment of this still mysterious disease. A virus was isolated from kidneys, tumors and meta-static lymph glands from cases of BEN. The material was obtained at operations of tumors of the urinary tract. The identity of the virus has yet to be established. In cases of BEN with tumors, anti-bodies were found in all the patients. The identity of the virus is the sub-ject of a companion paper (Riquelme C, Escors D, Ortego J, Sanchez CM, Uzelac-Keserovic B Enjuanes L. sub-mitted for publication). The evidence presented sug-gests strongly that as yet an unidentified virus is in-volved in the aetiology of BEN. There are still many unresolved questions concerning the putative virus.
PB  - Univerzitet u Nišu, Niš
T2  - Facta universitatis - series: Medicine and Biology
T1  - Virus isolation from the kidney, tumors and lymph nodes of patients with ben
EP  - 75
IS  - 1
SP  - 74
VL  - 9
UR  - https://hdl.handle.net/21.15107/rcub_intor_139
ER  - 
@article{
author = "Uzelac-Keserović, B. and Apostolov, K.",
year = "2002",
abstract = "This paper is based on two recent publications (1,2), and one submitted for publication (submittted for publi-cation). There is an important correction. In the two previous publications in Nephron it was stated that the virus isolated from the kidneys, the tumors and meta-static lymph glands was classified as a coronavirus (1,2). Subsequent more detailed investigations revealed that the virus should not be identified as a coronavirus (submittted for publication). However, the evidence presented in this work suggests strongly that the newly isolated virus is involved in the ethyology of BEN. The new findings open the possibility of reassessment of this still mysterious disease. A virus was isolated from kidneys, tumors and meta-static lymph glands from cases of BEN. The material was obtained at operations of tumors of the urinary tract. The identity of the virus has yet to be established. In cases of BEN with tumors, anti-bodies were found in all the patients. The identity of the virus is the sub-ject of a companion paper (Riquelme C, Escors D, Ortego J, Sanchez CM, Uzelac-Keserovic B Enjuanes L. sub-mitted for publication). The evidence presented sug-gests strongly that as yet an unidentified virus is in-volved in the aetiology of BEN. There are still many unresolved questions concerning the putative virus.",
publisher = "Univerzitet u Nišu, Niš",
journal = "Facta universitatis - series: Medicine and Biology",
title = "Virus isolation from the kidney, tumors and lymph nodes of patients with ben",
pages = "75-74",
number = "1",
volume = "9",
url = "https://hdl.handle.net/21.15107/rcub_intor_139"
}
Uzelac-Keserović, B.,& Apostolov, K.. (2002). Virus isolation from the kidney, tumors and lymph nodes of patients with ben. in Facta universitatis - series: Medicine and Biology
Univerzitet u Nišu, Niš., 9(1), 74-75.
https://hdl.handle.net/21.15107/rcub_intor_139
Uzelac-Keserović B, Apostolov K. Virus isolation from the kidney, tumors and lymph nodes of patients with ben. in Facta universitatis - series: Medicine and Biology. 2002;9(1):74-75.
https://hdl.handle.net/21.15107/rcub_intor_139 .
Uzelac-Keserović, B., Apostolov, K., "Virus isolation from the kidney, tumors and lymph nodes of patients with ben" in Facta universitatis - series: Medicine and Biology, 9, no. 1 (2002):74-75,
https://hdl.handle.net/21.15107/rcub_intor_139 .

Isolation of a coronavirus from urinary tract tumours of endemic Balkan nephropathy patients

Uzelac-Keserović, B.; Vasić, D.; Ikonomovski, J.; Bojanić, N.; Apostolov, K.

(Karger, Basel, 2000)

TY  - JOUR
AU  - Uzelac-Keserović, B.
AU  - Vasić, D.
AU  - Ikonomovski, J.
AU  - Bojanić, N.
AU  - Apostolov, K.
PY  - 2000
UR  - http://intor.torlakinstitut.com/handle/123456789/114
PB  - Karger, Basel
T2  - Nephron
T1  - Isolation of a coronavirus from urinary tract tumours of endemic Balkan nephropathy patients
EP  - 94
IS  - 1
SP  - 93
VL  - 86
DO  - 10.1159/000045720
ER  - 
@article{
author = "Uzelac-Keserović, B. and Vasić, D. and Ikonomovski, J. and Bojanić, N. and Apostolov, K.",
year = "2000",
publisher = "Karger, Basel",
journal = "Nephron",
title = "Isolation of a coronavirus from urinary tract tumours of endemic Balkan nephropathy patients",
pages = "94-93",
number = "1",
volume = "86",
doi = "10.1159/000045720"
}
Uzelac-Keserović, B., Vasić, D., Ikonomovski, J., Bojanić, N.,& Apostolov, K.. (2000). Isolation of a coronavirus from urinary tract tumours of endemic Balkan nephropathy patients. in Nephron
Karger, Basel., 86(1), 93-94.
https://doi.org/10.1159/000045720
Uzelac-Keserović B, Vasić D, Ikonomovski J, Bojanić N, Apostolov K. Isolation of a coronavirus from urinary tract tumours of endemic Balkan nephropathy patients. in Nephron. 2000;86(1):93-94.
doi:10.1159/000045720 .
Uzelac-Keserović, B., Vasić, D., Ikonomovski, J., Bojanić, N., Apostolov, K., "Isolation of a coronavirus from urinary tract tumours of endemic Balkan nephropathy patients" in Nephron, 86, no. 1 (2000):93-94,
https://doi.org/10.1159/000045720 . .
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Isolation of a coronavirus from kidney biopsies of endemic Balkan nephropathy patients

Uzelac-Keserović, B.; Spasić, P.; Bojanić, N.; Dimitrijević, J.; Lako, Branislav; Lepšanović, Z.; Kuljić-Kapulica, N.; Vasić, D.; Apostolov, K.

(S. Karger AG, 1999)

TY  - JOUR
AU  - Uzelac-Keserović, B.
AU  - Spasić, P.
AU  - Bojanić, N.
AU  - Dimitrijević, J.
AU  - Lako, Branislav
AU  - Lepšanović, Z.
AU  - Kuljić-Kapulica, N.
AU  - Vasić, D.
AU  - Apostolov, K.
PY  - 1999
UR  - http://intor.torlakinstitut.com/handle/123456789/109
AB  - Endemic Balkan nephropathy (EBN) is a kidney disease of unknown etiology limited to Bulgaria, Rumania and former Yugoslavia. Primary kidney tissue cultures were established as explants from tissue obtained at operations from 5 EBN patients with urinary tract tumors. Four out of the five biopsy specimens on extended culture incubation at 33°C yielded a coronavirus virus (EBNV) which was cytopathogenic for human fibroblast and Vero cells. In cells inoculated with EBNV, cytoplasmic immunofluorescence was found using antisera for human coronaviruses OC43 and 229E as well as the porcine transmissible gastroenteric virus and avian (chicken) bronchitis virus. In neutralization tests, EBNV failed to react with antisera to these viruses. Using hyperimmune serum raised with EBNV, positive cytoplasmic immunofluorescence was seen with cells infected with OC43, 229E, TGV and significantly with the kidney tissue of the biopsy specimens from the EBN patients. A screen for neutralizing antibody using the EBN virus revealed that 87.2% of EBN patients on dialysis were positive, also 74% of people from an endemic area were also positive, while only 13.5% from outside were positive. It is suggested that a coronavirus is involved in the etiology of the disease and that humans are an incidental host of a coronavirus zoonosis.
PB  - S. Karger AG
T2  - Nephron
T1  - Isolation of a coronavirus from kidney biopsies of endemic Balkan nephropathy patients
EP  - 145
IS  - 2
SP  - 141
VL  - 81
DO  - 10.1159/000045269
ER  - 
@article{
author = "Uzelac-Keserović, B. and Spasić, P. and Bojanić, N. and Dimitrijević, J. and Lako, Branislav and Lepšanović, Z. and Kuljić-Kapulica, N. and Vasić, D. and Apostolov, K.",
year = "1999",
abstract = "Endemic Balkan nephropathy (EBN) is a kidney disease of unknown etiology limited to Bulgaria, Rumania and former Yugoslavia. Primary kidney tissue cultures were established as explants from tissue obtained at operations from 5 EBN patients with urinary tract tumors. Four out of the five biopsy specimens on extended culture incubation at 33°C yielded a coronavirus virus (EBNV) which was cytopathogenic for human fibroblast and Vero cells. In cells inoculated with EBNV, cytoplasmic immunofluorescence was found using antisera for human coronaviruses OC43 and 229E as well as the porcine transmissible gastroenteric virus and avian (chicken) bronchitis virus. In neutralization tests, EBNV failed to react with antisera to these viruses. Using hyperimmune serum raised with EBNV, positive cytoplasmic immunofluorescence was seen with cells infected with OC43, 229E, TGV and significantly with the kidney tissue of the biopsy specimens from the EBN patients. A screen for neutralizing antibody using the EBN virus revealed that 87.2% of EBN patients on dialysis were positive, also 74% of people from an endemic area were also positive, while only 13.5% from outside were positive. It is suggested that a coronavirus is involved in the etiology of the disease and that humans are an incidental host of a coronavirus zoonosis.",
publisher = "S. Karger AG",
journal = "Nephron",
title = "Isolation of a coronavirus from kidney biopsies of endemic Balkan nephropathy patients",
pages = "145-141",
number = "2",
volume = "81",
doi = "10.1159/000045269"
}
Uzelac-Keserović, B., Spasić, P., Bojanić, N., Dimitrijević, J., Lako, B., Lepšanović, Z., Kuljić-Kapulica, N., Vasić, D.,& Apostolov, K.. (1999). Isolation of a coronavirus from kidney biopsies of endemic Balkan nephropathy patients. in Nephron
S. Karger AG., 81(2), 141-145.
https://doi.org/10.1159/000045269
Uzelac-Keserović B, Spasić P, Bojanić N, Dimitrijević J, Lako B, Lepšanović Z, Kuljić-Kapulica N, Vasić D, Apostolov K. Isolation of a coronavirus from kidney biopsies of endemic Balkan nephropathy patients. in Nephron. 1999;81(2):141-145.
doi:10.1159/000045269 .
Uzelac-Keserović, B., Spasić, P., Bojanić, N., Dimitrijević, J., Lako, Branislav, Lepšanović, Z., Kuljić-Kapulica, N., Vasić, D., Apostolov, K., "Isolation of a coronavirus from kidney biopsies of endemic Balkan nephropathy patients" in Nephron, 81, no. 2 (1999):141-145,
https://doi.org/10.1159/000045269 . .
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