Ivanović, Nevena

Link to this page

Authority KeyName Variants
orcid::0000-0001-6620-5007
  • Ivanović, Nevena (6)
Projects

Author's Bibliography

Changes In Parameters Of Immunological And Oxidative Status In Elite Athletes During Winter

Stanković, Ivan; Michalickova, Danica; Minić, Rajna; Kotur-Stevuljević, Jelena; Miljković, Milica; Kostić-Vučićević, Marija; Dikić, Nenad; Anđelković, Marija; Baralić, Ivana; Ivanović, Nevena; Đorđević, Brižita

(Lippincott Williams & Wilkins, Philadelphia, 2017)

TY  - CONF
AU  - Stanković, Ivan
AU  - Michalickova, Danica
AU  - Minić, Rajna
AU  - Kotur-Stevuljević, Jelena
AU  - Miljković, Milica
AU  - Kostić-Vučićević, Marija
AU  - Dikić, Nenad
AU  - Anđelković, Marija
AU  - Baralić, Ivana
AU  - Ivanović, Nevena
AU  - Đorđević, Brižita
PY  - 2017
UR  - http://intor.torlakinstitut.com/handle/123456789/481
PB  - Lippincott Williams & Wilkins, Philadelphia
C3  - Medicine and Science in Sports and Exercise
T1  - Changes In Parameters Of Immunological And Oxidative Status In Elite Athletes During Winter
EP  - 457
IS  - 5
SP  - 457
VL  - 49
DO  - 10.1249/01.mss.0000518140.98604.f5
UR  - conv_420
ER  - 
@conference{
author = "Stanković, Ivan and Michalickova, Danica and Minić, Rajna and Kotur-Stevuljević, Jelena and Miljković, Milica and Kostić-Vučićević, Marija and Dikić, Nenad and Anđelković, Marija and Baralić, Ivana and Ivanović, Nevena and Đorđević, Brižita",
year = "2017",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "Medicine and Science in Sports and Exercise",
title = "Changes In Parameters Of Immunological And Oxidative Status In Elite Athletes During Winter",
pages = "457-457",
number = "5",
volume = "49",
doi = "10.1249/01.mss.0000518140.98604.f5",
url = "conv_420"
}
Stanković, I., Michalickova, D., Minić, R., Kotur-Stevuljević, J., Miljković, M., Kostić-Vučićević, M., Dikić, N., Anđelković, M., Baralić, I., Ivanović, N.,& Đorđević, B.. (2017). Changes In Parameters Of Immunological And Oxidative Status In Elite Athletes During Winter. in Medicine and Science in Sports and Exercise
Lippincott Williams & Wilkins, Philadelphia., 49(5), 457-457.
https://doi.org/10.1249/01.mss.0000518140.98604.f5
conv_420
Stanković I, Michalickova D, Minić R, Kotur-Stevuljević J, Miljković M, Kostić-Vučićević M, Dikić N, Anđelković M, Baralić I, Ivanović N, Đorđević B. Changes In Parameters Of Immunological And Oxidative Status In Elite Athletes During Winter. in Medicine and Science in Sports and Exercise. 2017;49(5):457-457.
doi:10.1249/01.mss.0000518140.98604.f5
conv_420 .
Stanković, Ivan, Michalickova, Danica, Minić, Rajna, Kotur-Stevuljević, Jelena, Miljković, Milica, Kostić-Vučićević, Marija, Dikić, Nenad, Anđelković, Marija, Baralić, Ivana, Ivanović, Nevena, Đorđević, Brižita, "Changes In Parameters Of Immunological And Oxidative Status In Elite Athletes During Winter" in Medicine and Science in Sports and Exercise, 49, no. 5 (2017):457-457,
https://doi.org/10.1249/01.mss.0000518140.98604.f5 .,
conv_420 .

Active Lactobacillus rhamnosus LA68 or Lactobacillus plantarum WCFS1 administration positively influences liver fatty acid composition in mice on a HFD regime

Ivanović, Nevena; Minić, Rajna; Đuričić, Ivana; Radojević-Skodrić, Sanja; Živković, Irena; Šobajić, Slađana; Đorđević, Brižita

(Royal Soc Chemistry, Cambridge, 2016)

TY  - JOUR
AU  - Ivanović, Nevena
AU  - Minić, Rajna
AU  - Đuričić, Ivana
AU  - Radojević-Skodrić, Sanja
AU  - Živković, Irena
AU  - Šobajić, Slađana
AU  - Đorđević, Brižita
PY  - 2016
UR  - http://intor.torlakinstitut.com/handle/123456789/472
AB  - Western life style, and high calorie diet in particular is causing major health problems such as insulin resistance, hepatic steatosis and heart disease in the modern age. High fat diet (HFD) induces similar changes in mice, such as increased body weight, hypercholesterolemia and accumulation of triglycerides in the liver. These changes can be ameliorated by the administration of some Lactobacillus species. The focus of this study was to analyze the fatty acid content of liver, heart and brain tissues of mice fed HFD and administered with either Lactobacillus plantarum WCFS1 or Lactobacillus rhamnosus LA68, and to analyze the fatty acid content of these organs after a two months washout period. The fatty acid composition of mouse liver tissue changed significantly due to probiotic administration during a 12 weeks HFD regime and active Lactobacillus administration had a slightly reversing effect toward the standard mouse diet group, but after the washout period these changes disappeared. The fatty acid composition of the heart and brain tissues was significantly changed in the HFD regime but probiotic administration had no significant influence on the fatty acid profile of these two organs. Upon the 8 weeks washout period the only remaining beneficial effect was the significantly lower mouse weight in the supplemented groups compared to the HFD group.
PB  - Royal Soc Chemistry, Cambridge
T2  - Food & Function
T1  - Active Lactobacillus rhamnosus LA68 or Lactobacillus plantarum WCFS1 administration positively influences liver fatty acid composition in mice on a HFD regime
EP  - 2848
IS  - 6
SP  - 2840
VL  - 7
DO  - 10.1039/c5fo01432h
UR  - conv_389
ER  - 
@article{
author = "Ivanović, Nevena and Minić, Rajna and Đuričić, Ivana and Radojević-Skodrić, Sanja and Živković, Irena and Šobajić, Slađana and Đorđević, Brižita",
year = "2016",
abstract = "Western life style, and high calorie diet in particular is causing major health problems such as insulin resistance, hepatic steatosis and heart disease in the modern age. High fat diet (HFD) induces similar changes in mice, such as increased body weight, hypercholesterolemia and accumulation of triglycerides in the liver. These changes can be ameliorated by the administration of some Lactobacillus species. The focus of this study was to analyze the fatty acid content of liver, heart and brain tissues of mice fed HFD and administered with either Lactobacillus plantarum WCFS1 or Lactobacillus rhamnosus LA68, and to analyze the fatty acid content of these organs after a two months washout period. The fatty acid composition of mouse liver tissue changed significantly due to probiotic administration during a 12 weeks HFD regime and active Lactobacillus administration had a slightly reversing effect toward the standard mouse diet group, but after the washout period these changes disappeared. The fatty acid composition of the heart and brain tissues was significantly changed in the HFD regime but probiotic administration had no significant influence on the fatty acid profile of these two organs. Upon the 8 weeks washout period the only remaining beneficial effect was the significantly lower mouse weight in the supplemented groups compared to the HFD group.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food & Function",
title = "Active Lactobacillus rhamnosus LA68 or Lactobacillus plantarum WCFS1 administration positively influences liver fatty acid composition in mice on a HFD regime",
pages = "2848-2840",
number = "6",
volume = "7",
doi = "10.1039/c5fo01432h",
url = "conv_389"
}
Ivanović, N., Minić, R., Đuričić, I., Radojević-Skodrić, S., Živković, I., Šobajić, S.,& Đorđević, B.. (2016). Active Lactobacillus rhamnosus LA68 or Lactobacillus plantarum WCFS1 administration positively influences liver fatty acid composition in mice on a HFD regime. in Food & Function
Royal Soc Chemistry, Cambridge., 7(6), 2840-2848.
https://doi.org/10.1039/c5fo01432h
conv_389
Ivanović N, Minić R, Đuričić I, Radojević-Skodrić S, Živković I, Šobajić S, Đorđević B. Active Lactobacillus rhamnosus LA68 or Lactobacillus plantarum WCFS1 administration positively influences liver fatty acid composition in mice on a HFD regime. in Food & Function. 2016;7(6):2840-2848.
doi:10.1039/c5fo01432h
conv_389 .
Ivanović, Nevena, Minić, Rajna, Đuričić, Ivana, Radojević-Skodrić, Sanja, Živković, Irena, Šobajić, Slađana, Đorđević, Brižita, "Active Lactobacillus rhamnosus LA68 or Lactobacillus plantarum WCFS1 administration positively influences liver fatty acid composition in mice on a HFD regime" in Food & Function, 7, no. 6 (2016):2840-2848,
https://doi.org/10.1039/c5fo01432h .,
conv_389 .
1
9
7
9

Lactobacillus Helveticus L10 Supplementation Modulates Immunity Parameters in Elite Athletes

Đorđević, Brižita; Marinković, Danica; Minić, Rajna; Ivanović, Nevena; Dikić, Nenad; Anđelković, Marija; Živković, Irena; Stanković, Ivan

(Lippincott Williams & Wilkins, Philadelphia, 2016)

TY  - CONF
AU  - Đorđević, Brižita
AU  - Marinković, Danica
AU  - Minić, Rajna
AU  - Ivanović, Nevena
AU  - Dikić, Nenad
AU  - Anđelković, Marija
AU  - Živković, Irena
AU  - Stanković, Ivan
PY  - 2016
UR  - http://intor.torlakinstitut.com/handle/123456789/452
PB  - Lippincott Williams & Wilkins, Philadelphia
C3  - Medicine and Science in Sports and Exercise
T1  - Lactobacillus Helveticus L10 Supplementation Modulates Immunity Parameters in Elite Athletes
EP  - 246
IS  - 5
SP  - 246
VL  - 48
DO  - 10.1249/01.mss.0000485740.06462.11
UR  - conv_418
ER  - 
@conference{
author = "Đorđević, Brižita and Marinković, Danica and Minić, Rajna and Ivanović, Nevena and Dikić, Nenad and Anđelković, Marija and Živković, Irena and Stanković, Ivan",
year = "2016",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "Medicine and Science in Sports and Exercise",
title = "Lactobacillus Helveticus L10 Supplementation Modulates Immunity Parameters in Elite Athletes",
pages = "246-246",
number = "5",
volume = "48",
doi = "10.1249/01.mss.0000485740.06462.11",
url = "conv_418"
}
Đorđević, B., Marinković, D., Minić, R., Ivanović, N., Dikić, N., Anđelković, M., Živković, I.,& Stanković, I.. (2016). Lactobacillus Helveticus L10 Supplementation Modulates Immunity Parameters in Elite Athletes. in Medicine and Science in Sports and Exercise
Lippincott Williams & Wilkins, Philadelphia., 48(5), 246-246.
https://doi.org/10.1249/01.mss.0000485740.06462.11
conv_418
Đorđević B, Marinković D, Minić R, Ivanović N, Dikić N, Anđelković M, Živković I, Stanković I. Lactobacillus Helveticus L10 Supplementation Modulates Immunity Parameters in Elite Athletes. in Medicine and Science in Sports and Exercise. 2016;48(5):246-246.
doi:10.1249/01.mss.0000485740.06462.11
conv_418 .
Đorđević, Brižita, Marinković, Danica, Minić, Rajna, Ivanović, Nevena, Dikić, Nenad, Anđelković, Marija, Živković, Irena, Stanković, Ivan, "Lactobacillus Helveticus L10 Supplementation Modulates Immunity Parameters in Elite Athletes" in Medicine and Science in Sports and Exercise, 48, no. 5 (2016):246-246,
https://doi.org/10.1249/01.mss.0000485740.06462.11 .,
conv_418 .

Lactobacillus rhamnosus LA68 and Lactobacillus plantarum WCFS1 differently influence metabolic and immunological parameters in high fat diet-induced hypercholesterolemia and hepatic steatosis

Ivanović, Nevena; Minić, Rajna; Dimitrijević, Ljiljana; Radojević-Skodrić, Sanja; Živković, Irena; Đorđević, Brižita

(Royal Soc Chemistry, Cambridge, 2015)

TY  - JOUR
AU  - Ivanović, Nevena
AU  - Minić, Rajna
AU  - Dimitrijević, Ljiljana
AU  - Radojević-Skodrić, Sanja
AU  - Živković, Irena
AU  - Đorđević, Brižita
PY  - 2015
UR  - http://intor.torlakinstitut.com/handle/123456789/445
AB  - In this study, two Lactobacillus strains (L. rhamnosus LA68 and L. plantarum WCFS1) were evaluated for their effects on high fat diet induced pathology in mice. The aim was to determine whether the administration of lactic acid bacteria had beneficial effects on ameliorating pathology. C57BL/6 mice fed a high fat diet were orally administered with the Lactobacillus strains. Both the metabolic and immunological parameters were analyzed. The administration of both of the strains had beneficial effects on mouse weight, serum cholesterol, TNF-alpha levels and liver histology. LA68 lowered the total cholesterol and HDL levels more prominently, whereas WCFS1 was more potent in lowering the TG and LDL levels. Leptin and adiponectin levels were increased in all experimental groups to different extents. The administration of L. plantarum WCFS1 led to a marked increase in leptin levels, as well as an increase in CD3+CD4+ and CD3+CD8+ cells, and a decrease of CD25+ cells, and had a lowering effect on IL-6 production and cell metabolic activity. In conclusion, active administration of both Lactobacillus strains had a positive effect on HFD-induced pathology. Although both of the tested strains had beneficial effects, oral administration of WCFS1 increased leptin levels and had a more prominent immunomodulatory effect, which should be taken into consideration in case of humane usage.
PB  - Royal Soc Chemistry, Cambridge
T2  - Food & Function
T1  - Lactobacillus rhamnosus LA68 and Lactobacillus plantarum WCFS1 differently influence metabolic and immunological parameters in high fat diet-induced hypercholesterolemia and hepatic steatosis
EP  - 565
IS  - 2
SP  - 558
VL  - 6
DO  - 10.1039/c4fo00843j
UR  - conv_355
ER  - 
@article{
author = "Ivanović, Nevena and Minić, Rajna and Dimitrijević, Ljiljana and Radojević-Skodrić, Sanja and Živković, Irena and Đorđević, Brižita",
year = "2015",
abstract = "In this study, two Lactobacillus strains (L. rhamnosus LA68 and L. plantarum WCFS1) were evaluated for their effects on high fat diet induced pathology in mice. The aim was to determine whether the administration of lactic acid bacteria had beneficial effects on ameliorating pathology. C57BL/6 mice fed a high fat diet were orally administered with the Lactobacillus strains. Both the metabolic and immunological parameters were analyzed. The administration of both of the strains had beneficial effects on mouse weight, serum cholesterol, TNF-alpha levels and liver histology. LA68 lowered the total cholesterol and HDL levels more prominently, whereas WCFS1 was more potent in lowering the TG and LDL levels. Leptin and adiponectin levels were increased in all experimental groups to different extents. The administration of L. plantarum WCFS1 led to a marked increase in leptin levels, as well as an increase in CD3+CD4+ and CD3+CD8+ cells, and a decrease of CD25+ cells, and had a lowering effect on IL-6 production and cell metabolic activity. In conclusion, active administration of both Lactobacillus strains had a positive effect on HFD-induced pathology. Although both of the tested strains had beneficial effects, oral administration of WCFS1 increased leptin levels and had a more prominent immunomodulatory effect, which should be taken into consideration in case of humane usage.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "Food & Function",
title = "Lactobacillus rhamnosus LA68 and Lactobacillus plantarum WCFS1 differently influence metabolic and immunological parameters in high fat diet-induced hypercholesterolemia and hepatic steatosis",
pages = "565-558",
number = "2",
volume = "6",
doi = "10.1039/c4fo00843j",
url = "conv_355"
}
Ivanović, N., Minić, R., Dimitrijević, L., Radojević-Skodrić, S., Živković, I.,& Đorđević, B.. (2015). Lactobacillus rhamnosus LA68 and Lactobacillus plantarum WCFS1 differently influence metabolic and immunological parameters in high fat diet-induced hypercholesterolemia and hepatic steatosis. in Food & Function
Royal Soc Chemistry, Cambridge., 6(2), 558-565.
https://doi.org/10.1039/c4fo00843j
conv_355
Ivanović N, Minić R, Dimitrijević L, Radojević-Skodrić S, Živković I, Đorđević B. Lactobacillus rhamnosus LA68 and Lactobacillus plantarum WCFS1 differently influence metabolic and immunological parameters in high fat diet-induced hypercholesterolemia and hepatic steatosis. in Food & Function. 2015;6(2):558-565.
doi:10.1039/c4fo00843j
conv_355 .
Ivanović, Nevena, Minić, Rajna, Dimitrijević, Ljiljana, Radojević-Skodrić, Sanja, Živković, Irena, Đorđević, Brižita, "Lactobacillus rhamnosus LA68 and Lactobacillus plantarum WCFS1 differently influence metabolic and immunological parameters in high fat diet-induced hypercholesterolemia and hepatic steatosis" in Food & Function, 6, no. 2 (2015):558-565,
https://doi.org/10.1039/c4fo00843j .,
conv_355 .
28
22
24

Brain and liver fatty acid composition changes upon consumption of Lactobacillus rhamnosus LA68

Ivanović, Nevena; Minić, Rajna; Đuričić, Ivana; Dimitrijević, Ljiljana; Šobajić, Slađana; Živković, Irena; Đorđević, Brižita

(Taylor & Francis Ltd, Abingdon, 2015)

TY  - JOUR
AU  - Ivanović, Nevena
AU  - Minić, Rajna
AU  - Đuričić, Ivana
AU  - Dimitrijević, Ljiljana
AU  - Šobajić, Slađana
AU  - Živković, Irena
AU  - Đorđević, Brižita
PY  - 2015
UR  - http://intor.torlakinstitut.com/handle/123456789/443
AB  - Recent reports suggest that the metabolic activity of the enteric microbiota may influence the fatty acid composition of the host tissue. There are many studies dealing with the influence of lactobacilli on various pathological conditions, and some of the effects are strain-specific. This study was designed to test the effects of a particular Lactobacillus strain, Lactobacillus rhamnosus LA68 on fatty acid composition of the liver and the brain of C57BL/6 mice in the absence of an underlying pathological condition. Female mice were supplemented with live L. rhamnosus LA68 bacteria for the duration of 1 month. Serum biochemistry was analyzed and liver and brain fatty acid composition was assessed by gas-liquid chromatography. Significant changes in liver and brain fatty acid composition were detected. In the liver tissue we detected an increase in palmitoleic acid (p = 0.038), while in the brain compartment we found an increase in palmitic (p = 0.042), stearic (p = 0.017), arachidonic acid (p = 0.009) and docosahexaenoic acid (p = 0.004) for control versus experimental group. These results show discrete changes caused by LA68 strain consumption. Even short duration of administration of LA68 influences the fatty acid composition of the host which adds to the existing knowledge about Lactobacillus host interaction, and adds to the growing knowledge of metabolic intervention possibilities.
PB  - Taylor & Francis Ltd, Abingdon
T2  - International Journal of Food Sciences and Nutrition
T1  - Brain and liver fatty acid composition changes upon consumption of Lactobacillus rhamnosus LA68
EP  - 97
IS  - 1
SP  - 93
VL  - 66
DO  - 10.3109/09637486.2014.979313
UR  - conv_353
ER  - 
@article{
author = "Ivanović, Nevena and Minić, Rajna and Đuričić, Ivana and Dimitrijević, Ljiljana and Šobajić, Slađana and Živković, Irena and Đorđević, Brižita",
year = "2015",
abstract = "Recent reports suggest that the metabolic activity of the enteric microbiota may influence the fatty acid composition of the host tissue. There are many studies dealing with the influence of lactobacilli on various pathological conditions, and some of the effects are strain-specific. This study was designed to test the effects of a particular Lactobacillus strain, Lactobacillus rhamnosus LA68 on fatty acid composition of the liver and the brain of C57BL/6 mice in the absence of an underlying pathological condition. Female mice were supplemented with live L. rhamnosus LA68 bacteria for the duration of 1 month. Serum biochemistry was analyzed and liver and brain fatty acid composition was assessed by gas-liquid chromatography. Significant changes in liver and brain fatty acid composition were detected. In the liver tissue we detected an increase in palmitoleic acid (p = 0.038), while in the brain compartment we found an increase in palmitic (p = 0.042), stearic (p = 0.017), arachidonic acid (p = 0.009) and docosahexaenoic acid (p = 0.004) for control versus experimental group. These results show discrete changes caused by LA68 strain consumption. Even short duration of administration of LA68 influences the fatty acid composition of the host which adds to the existing knowledge about Lactobacillus host interaction, and adds to the growing knowledge of metabolic intervention possibilities.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "International Journal of Food Sciences and Nutrition",
title = "Brain and liver fatty acid composition changes upon consumption of Lactobacillus rhamnosus LA68",
pages = "97-93",
number = "1",
volume = "66",
doi = "10.3109/09637486.2014.979313",
url = "conv_353"
}
Ivanović, N., Minić, R., Đuričić, I., Dimitrijević, L., Šobajić, S., Živković, I.,& Đorđević, B.. (2015). Brain and liver fatty acid composition changes upon consumption of Lactobacillus rhamnosus LA68. in International Journal of Food Sciences and Nutrition
Taylor & Francis Ltd, Abingdon., 66(1), 93-97.
https://doi.org/10.3109/09637486.2014.979313
conv_353
Ivanović N, Minić R, Đuričić I, Dimitrijević L, Šobajić S, Živković I, Đorđević B. Brain and liver fatty acid composition changes upon consumption of Lactobacillus rhamnosus LA68. in International Journal of Food Sciences and Nutrition. 2015;66(1):93-97.
doi:10.3109/09637486.2014.979313
conv_353 .
Ivanović, Nevena, Minić, Rajna, Đuričić, Ivana, Dimitrijević, Ljiljana, Šobajić, Slađana, Živković, Irena, Đorđević, Brižita, "Brain and liver fatty acid composition changes upon consumption of Lactobacillus rhamnosus LA68" in International Journal of Food Sciences and Nutrition, 66, no. 1 (2015):93-97,
https://doi.org/10.3109/09637486.2014.979313 .,
conv_353 .
1
7
5
6

Effects of Lactobacillus rhamnosus LA68 on the immune system of C57BL/6 mice upon oral administration

Dimitrijević, Rajna; Ivanović, Nevena; Mathiesen, Geir; Petrušić, Vladimir; Živković, Irena; Đorđević, Brižita; Dimitrijević, Ljiljana

(Cambridge Univ Press, New York, 2014)

TY  - JOUR
AU  - Dimitrijević, Rajna
AU  - Ivanović, Nevena
AU  - Mathiesen, Geir
AU  - Petrušić, Vladimir
AU  - Živković, Irena
AU  - Đorđević, Brižita
AU  - Dimitrijević, Ljiljana
PY  - 2014
UR  - http://intor.torlakinstitut.com/handle/123456789/398
AB  - Probiotic bacteria have been used in human nutrition for centuries and are now attracting more attention. In order to examine the immunological aspects of probiotic consumption, Lactobacillus rhamnosus LA68 was orally administrated using gavage to healthy C57BL/6 mice. After one month splenocytes were isolated, and analysed by flow cytometry. The magnitude of splenocyte proliferation upon stimulation with lipopolysaccharide and peptidoglycan and cytokine levels (IFN-gamma, IL-6, IL-10 and IL-17) was assessed. Cytokine levels in the serum were also analysed. Oral application of strain LA68 leads to a significant decrease of CD3+, CD25+ and CD19+ cells, and an increase of CD11b+ and CD16/CD32+ positive cell populations in the mouse spleen. Increased sensitivity to stimulation through proliferation and IL-6 secretion was detected. Increased serum IFN-gamma and decreased IL-10 levels were found. Our results show increased responsiveness of splenocytes, activation of the Th1 type of immune response, and a shift of leucocyte populations towards monocyte/granulocyte populations.
PB  - Cambridge Univ Press, New York
T2  - Journal of Dairy Research
T1  - Effects of Lactobacillus rhamnosus LA68 on the immune system of C57BL/6 mice upon oral administration
EP  - 207
IS  - 2
SP  - 202
VL  - 81
DO  - 10.1017/S0022029914000028
UR  - conv_338
ER  - 
@article{
author = "Dimitrijević, Rajna and Ivanović, Nevena and Mathiesen, Geir and Petrušić, Vladimir and Živković, Irena and Đorđević, Brižita and Dimitrijević, Ljiljana",
year = "2014",
abstract = "Probiotic bacteria have been used in human nutrition for centuries and are now attracting more attention. In order to examine the immunological aspects of probiotic consumption, Lactobacillus rhamnosus LA68 was orally administrated using gavage to healthy C57BL/6 mice. After one month splenocytes were isolated, and analysed by flow cytometry. The magnitude of splenocyte proliferation upon stimulation with lipopolysaccharide and peptidoglycan and cytokine levels (IFN-gamma, IL-6, IL-10 and IL-17) was assessed. Cytokine levels in the serum were also analysed. Oral application of strain LA68 leads to a significant decrease of CD3+, CD25+ and CD19+ cells, and an increase of CD11b+ and CD16/CD32+ positive cell populations in the mouse spleen. Increased sensitivity to stimulation through proliferation and IL-6 secretion was detected. Increased serum IFN-gamma and decreased IL-10 levels were found. Our results show increased responsiveness of splenocytes, activation of the Th1 type of immune response, and a shift of leucocyte populations towards monocyte/granulocyte populations.",
publisher = "Cambridge Univ Press, New York",
journal = "Journal of Dairy Research",
title = "Effects of Lactobacillus rhamnosus LA68 on the immune system of C57BL/6 mice upon oral administration",
pages = "207-202",
number = "2",
volume = "81",
doi = "10.1017/S0022029914000028",
url = "conv_338"
}
Dimitrijević, R., Ivanović, N., Mathiesen, G., Petrušić, V., Živković, I., Đorđević, B.,& Dimitrijević, L.. (2014). Effects of Lactobacillus rhamnosus LA68 on the immune system of C57BL/6 mice upon oral administration. in Journal of Dairy Research
Cambridge Univ Press, New York., 81(2), 202-207.
https://doi.org/10.1017/S0022029914000028
conv_338
Dimitrijević R, Ivanović N, Mathiesen G, Petrušić V, Živković I, Đorđević B, Dimitrijević L. Effects of Lactobacillus rhamnosus LA68 on the immune system of C57BL/6 mice upon oral administration. in Journal of Dairy Research. 2014;81(2):202-207.
doi:10.1017/S0022029914000028
conv_338 .
Dimitrijević, Rajna, Ivanović, Nevena, Mathiesen, Geir, Petrušić, Vladimir, Živković, Irena, Đorđević, Brižita, Dimitrijević, Ljiljana, "Effects of Lactobacillus rhamnosus LA68 on the immune system of C57BL/6 mice upon oral administration" in Journal of Dairy Research, 81, no. 2 (2014):202-207,
https://doi.org/10.1017/S0022029914000028 .,
conv_338 .
1
19
14
17