Đurić, Marija

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  • Đurić, Marija (2)
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Supplementary information for the article: Micić, M.; Antonijević, Đ.; Milutinović-Smiljanić, S.; Trisić, D.; Colović, B.; Kosanović, D.; Prokić, B.; Vasić, J.; Zivković, S.; Milašin, J.; Danilović, V.; Đurić, M.; Jokanović, V. Developing a Novel Resorptive Hydroxyapatite-Based Bone Substitute for over-Critical Size Defect Reconstruction: Physicochemical and Biological Characterization and Proof of Concept in Segmental Rabbit’s Ulna Reconstruction. Biomedical Engineering-Biomedizinische Technik 2020, 65 (4), 491–505. https://doi.org/10.1515/bmt-2019-0218.

Micić, Milutin; Antonijević, Đorđe; Milutinović-Smiljanić, Sanja; Trisić, Dijana; Colović, Božana; Kosanović, Dejana; Prokić, Bogomir; Vasić, Jugoslav; Zivković, Slavoljub; Milašin, Jelena; Danilović, Vesna; Đurić, Marija; Jokanović, Vukoman

(Walter De Gruyter Gmbh, Berlin, 2020)

TY  - DATA
AU  - Micić, Milutin
AU  - Antonijević, Đorđe
AU  - Milutinović-Smiljanić, Sanja
AU  - Trisić, Dijana
AU  - Colović, Božana
AU  - Kosanović, Dejana
AU  - Prokić, Bogomir
AU  - Vasić, Jugoslav
AU  - Zivković, Slavoljub
AU  - Milašin, Jelena
AU  - Danilović, Vesna
AU  - Đurić, Marija
AU  - Jokanović, Vukoman
PY  - 2020
UR  - http://intor.torlakinstitut.com/handle/123456789/661
AB  - Figure 1S. Change of the Ca concentration in the solution containing investigated nHAP granules with time.  Figure 2S. Change of the Ca concentration with time in biological apatite (BioOss).  Figure 3S. The correlation of the ALBO-OS compressive strenght and the time of the material’s soaking in Hank’s solution. Table 1S. Reference point indentation outcomes of the ALBOOS. MH – microhardness, ID 1st - 1st Cycle Indentation Distance; US 1st - 1st Cycle Unloading Slope; CID 1st -1st Cycle Creep Indentation Distance; TID - Total Indentation Distance; IDI - Indentation Distance Increase; Avg CID - Avg Creep Indentation Distance; Avg US - Average Unloading Slope; Avg US - Average Unloading Slope; Avg LS - Average Loading Slope; Avg ED - Average Energy Dissipated.  Table 2S. Ph of nHAP after soaking in simulated body fluid. Figure 4S. Microacrhitectural and structural characteristics of nHAP in vitro and in contact with bone tissue in vivo. Adequate microstructure and surface nanotopography provide good environment for cells infiltration in vivo. Note the presence of porous paterns within material structure in vivo as well as the lamellar structure of ALBO-OS.  Figure 5S. Schematic representation of the extruder design in custom made laboratory 3D printer: from technical reasons, 3D printer was modified to include two extruders: 1 – syringe extruder, 1.1 – glass syringe, 1.2 – external frame of the extruder 1, 1.3 – electrical heater coil, 1.4 –metal piston of the syringe, 1.5 – syringe nozzle (0,8mm in diameter), 1.6 – gears of the piston drive, 1.7 – piston drive motor with reduction, 1.8 – HAP PLA mixture, 2 – PLA extruder, 2.1 – heater block of the PLA extruder, 2.2 – extruder cooler, 2.3 – PLA extruder motor drive with reduction, 2.4 – PLA filament 1.75mm in diameter, 2.5 – PLA extruder nozzle 0,4mm in diameter.  Figure 6S. Paste extruder attached to the head of the printer, with removed electrical heater coil, so the syringe with the metal piston can be visible.  A) The engineered construct used for the experiments and B) its structure after magnification (X200). C-E) Wettability of the construct. Administration of the reference liquid droplet on the construct surface. F) Histogram showing the time required for reference liquid to completely wet the construct surface. Note that the droplet is absorbed within the part of the second.
PB  - Walter De Gruyter Gmbh, Berlin
T2  - Biomedical Engineering-Biomedizinische Technik
T1  - Supplementary information for the article: Micić, M.; Antonijević, Đ.; Milutinović-Smiljanić, S.; Trisić, D.;  Colović, B.; Kosanović, D.; Prokić, B.; Vasić, J.; Zivković, S.; Milašin, J.; Danilović, V.; Đurić, M.; Jokanović, V. Developing  a Novel Resorptive Hydroxyapatite-Based Bone Substitute for over-Critical Size Defect Reconstruction: Physicochemical and  Biological Characterization and Proof of Concept in Segmental Rabbit’s Ulna Reconstruction. Biomedical  Engineering-Biomedizinische Technik 2020, 65 (4), 491–505. https://doi.org/10.1515/bmt-2019-0218.
UR  - https://hdl.handle.net/21.15107/rcub_intor_661
ER  - 
@misc{
author = "Micić, Milutin and Antonijević, Đorđe and Milutinović-Smiljanić, Sanja and Trisić, Dijana and Colović, Božana and Kosanović, Dejana and Prokić, Bogomir and Vasić, Jugoslav and Zivković, Slavoljub and Milašin, Jelena and Danilović, Vesna and Đurić, Marija and Jokanović, Vukoman",
year = "2020",
abstract = "Figure 1S. Change of the Ca concentration in the solution containing investigated nHAP granules with time.  Figure 2S. Change of the Ca concentration with time in biological apatite (BioOss).  Figure 3S. The correlation of the ALBO-OS compressive strenght and the time of the material’s soaking in Hank’s solution. Table 1S. Reference point indentation outcomes of the ALBOOS. MH – microhardness, ID 1st - 1st Cycle Indentation Distance; US 1st - 1st Cycle Unloading Slope; CID 1st -1st Cycle Creep Indentation Distance; TID - Total Indentation Distance; IDI - Indentation Distance Increase; Avg CID - Avg Creep Indentation Distance; Avg US - Average Unloading Slope; Avg US - Average Unloading Slope; Avg LS - Average Loading Slope; Avg ED - Average Energy Dissipated.  Table 2S. Ph of nHAP after soaking in simulated body fluid. Figure 4S. Microacrhitectural and structural characteristics of nHAP in vitro and in contact with bone tissue in vivo. Adequate microstructure and surface nanotopography provide good environment for cells infiltration in vivo. Note the presence of porous paterns within material structure in vivo as well as the lamellar structure of ALBO-OS.  Figure 5S. Schematic representation of the extruder design in custom made laboratory 3D printer: from technical reasons, 3D printer was modified to include two extruders: 1 – syringe extruder, 1.1 – glass syringe, 1.2 – external frame of the extruder 1, 1.3 – electrical heater coil, 1.4 –metal piston of the syringe, 1.5 – syringe nozzle (0,8mm in diameter), 1.6 – gears of the piston drive, 1.7 – piston drive motor with reduction, 1.8 – HAP PLA mixture, 2 – PLA extruder, 2.1 – heater block of the PLA extruder, 2.2 – extruder cooler, 2.3 – PLA extruder motor drive with reduction, 2.4 – PLA filament 1.75mm in diameter, 2.5 – PLA extruder nozzle 0,4mm in diameter.  Figure 6S. Paste extruder attached to the head of the printer, with removed electrical heater coil, so the syringe with the metal piston can be visible.  A) The engineered construct used for the experiments and B) its structure after magnification (X200). C-E) Wettability of the construct. Administration of the reference liquid droplet on the construct surface. F) Histogram showing the time required for reference liquid to completely wet the construct surface. Note that the droplet is absorbed within the part of the second.",
publisher = "Walter De Gruyter Gmbh, Berlin",
journal = "Biomedical Engineering-Biomedizinische Technik",
title = "Supplementary information for the article: Micić, M.; Antonijević, Đ.; Milutinović-Smiljanić, S.; Trisić, D.;  Colović, B.; Kosanović, D.; Prokić, B.; Vasić, J.; Zivković, S.; Milašin, J.; Danilović, V.; Đurić, M.; Jokanović, V. Developing  a Novel Resorptive Hydroxyapatite-Based Bone Substitute for over-Critical Size Defect Reconstruction: Physicochemical and  Biological Characterization and Proof of Concept in Segmental Rabbit’s Ulna Reconstruction. Biomedical  Engineering-Biomedizinische Technik 2020, 65 (4), 491–505. https://doi.org/10.1515/bmt-2019-0218.",
url = "https://hdl.handle.net/21.15107/rcub_intor_661"
}
Micić, M., Antonijević, Đ., Milutinović-Smiljanić, S., Trisić, D., Colović, B., Kosanović, D., Prokić, B., Vasić, J., Zivković, S., Milašin, J., Danilović, V., Đurić, M.,& Jokanović, V.. (2020). Supplementary information for the article: Micić, M.; Antonijević, Đ.; Milutinović-Smiljanić, S.; Trisić, D.;  Colović, B.; Kosanović, D.; Prokić, B.; Vasić, J.; Zivković, S.; Milašin, J.; Danilović, V.; Đurić, M.; Jokanović, V. Developing  a Novel Resorptive Hydroxyapatite-Based Bone Substitute for over-Critical Size Defect Reconstruction: Physicochemical and  Biological Characterization and Proof of Concept in Segmental Rabbit’s Ulna Reconstruction. Biomedical  Engineering-Biomedizinische Technik 2020, 65 (4), 491–505. https://doi.org/10.1515/bmt-2019-0218.. in Biomedical Engineering-Biomedizinische Technik
Walter De Gruyter Gmbh, Berlin..
https://hdl.handle.net/21.15107/rcub_intor_661
Micić M, Antonijević Đ, Milutinović-Smiljanić S, Trisić D, Colović B, Kosanović D, Prokić B, Vasić J, Zivković S, Milašin J, Danilović V, Đurić M, Jokanović V. Supplementary information for the article: Micić, M.; Antonijević, Đ.; Milutinović-Smiljanić, S.; Trisić, D.;  Colović, B.; Kosanović, D.; Prokić, B.; Vasić, J.; Zivković, S.; Milašin, J.; Danilović, V.; Đurić, M.; Jokanović, V. Developing  a Novel Resorptive Hydroxyapatite-Based Bone Substitute for over-Critical Size Defect Reconstruction: Physicochemical and  Biological Characterization and Proof of Concept in Segmental Rabbit’s Ulna Reconstruction. Biomedical  Engineering-Biomedizinische Technik 2020, 65 (4), 491–505. https://doi.org/10.1515/bmt-2019-0218.. in Biomedical Engineering-Biomedizinische Technik. 2020;.
https://hdl.handle.net/21.15107/rcub_intor_661 .
Micić, Milutin, Antonijević, Đorđe, Milutinović-Smiljanić, Sanja, Trisić, Dijana, Colović, Božana, Kosanović, Dejana, Prokić, Bogomir, Vasić, Jugoslav, Zivković, Slavoljub, Milašin, Jelena, Danilović, Vesna, Đurić, Marija, Jokanović, Vukoman, "Supplementary information for the article: Micić, M.; Antonijević, Đ.; Milutinović-Smiljanić, S.; Trisić, D.;  Colović, B.; Kosanović, D.; Prokić, B.; Vasić, J.; Zivković, S.; Milašin, J.; Danilović, V.; Đurić, M.; Jokanović, V. Developing  a Novel Resorptive Hydroxyapatite-Based Bone Substitute for over-Critical Size Defect Reconstruction: Physicochemical and  Biological Characterization and Proof of Concept in Segmental Rabbit’s Ulna Reconstruction. Biomedical  Engineering-Biomedizinische Technik 2020, 65 (4), 491–505. https://doi.org/10.1515/bmt-2019-0218." in Biomedical Engineering-Biomedizinische Technik (2020),
https://hdl.handle.net/21.15107/rcub_intor_661 .

Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction

Micić, Milutin; Antonijević, Đorđe; Milutinović-Smiljanić, Sanja; Trisić, Dijana; Colović, Božana; Kosanović, Dejana; Prokić, Bogomir; Vasić, Jugoslav; Zivković, Slavoljub; Milašin, Jelena; Danilović, Vesna; Đurić, Marija; Jokanović, Vukoman

(Walter De Gruyter Gmbh, Berlin, 2020)

TY  - JOUR
AU  - Micić, Milutin
AU  - Antonijević, Đorđe
AU  - Milutinović-Smiljanić, Sanja
AU  - Trisić, Dijana
AU  - Colović, Božana
AU  - Kosanović, Dejana
AU  - Prokić, Bogomir
AU  - Vasić, Jugoslav
AU  - Zivković, Slavoljub
AU  - Milašin, Jelena
AU  - Danilović, Vesna
AU  - Đurić, Marija
AU  - Jokanović, Vukoman
PY  - 2020
UR  - http://intor.torlakinstitut.com/handle/123456789/542
AB  - The aim of this study was to develop novel hydroxyapatite (HAP)-based bioactive bone replacement materials for segmental osteotomy reconstruction. Customized three-dimensional (3D) bone construct was manufactured from nanohydroxyapatite (nHAP) with poly(lactide-co-glycolide) (PLGA) coating using 3D models derived from the computed tomography (CT) scanning of the rabbit's ulna and gradient 3D printing of the bone substitute mimicking the anatomical shape of the natural bone defect. Engineered construct revealed adequate micro-architectural design for successful bone regeneration having a total porosity of 64% and an average pore size of 256 mu m. Radiography and micro-CT analysis depicted new bone apposition through the whole length of the reconstructed ulna with a small area of non-resorbed construct in the central area of defect. Histological analysis revealed new bone formation with both endochondral and endesmal type of ossification. Immunohistochemistry analysis depicted the presence of bone formation indicators - bone morphogenetic protein (BMP), osteocalcin (OCN) and osteopontin (OPN) within newly formed bone. Manufactured personalized construct acts as a "smart" responsive biomaterial capable of modulating the functionality and potential for the personalized bone reconstruction on a clinically relevant length scale.
PB  - Walter De Gruyter Gmbh, Berlin
T2  - Biomedical Engineering-Biomedizinische Technik
T1  - Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction
EP  - 505
IS  - 4
SP  - 491
VL  - 65
DO  - 10.1515/bmt-2019-0218
ER  - 
@article{
author = "Micić, Milutin and Antonijević, Đorđe and Milutinović-Smiljanić, Sanja and Trisić, Dijana and Colović, Božana and Kosanović, Dejana and Prokić, Bogomir and Vasić, Jugoslav and Zivković, Slavoljub and Milašin, Jelena and Danilović, Vesna and Đurić, Marija and Jokanović, Vukoman",
year = "2020",
abstract = "The aim of this study was to develop novel hydroxyapatite (HAP)-based bioactive bone replacement materials for segmental osteotomy reconstruction. Customized three-dimensional (3D) bone construct was manufactured from nanohydroxyapatite (nHAP) with poly(lactide-co-glycolide) (PLGA) coating using 3D models derived from the computed tomography (CT) scanning of the rabbit's ulna and gradient 3D printing of the bone substitute mimicking the anatomical shape of the natural bone defect. Engineered construct revealed adequate micro-architectural design for successful bone regeneration having a total porosity of 64% and an average pore size of 256 mu m. Radiography and micro-CT analysis depicted new bone apposition through the whole length of the reconstructed ulna with a small area of non-resorbed construct in the central area of defect. Histological analysis revealed new bone formation with both endochondral and endesmal type of ossification. Immunohistochemistry analysis depicted the presence of bone formation indicators - bone morphogenetic protein (BMP), osteocalcin (OCN) and osteopontin (OPN) within newly formed bone. Manufactured personalized construct acts as a "smart" responsive biomaterial capable of modulating the functionality and potential for the personalized bone reconstruction on a clinically relevant length scale.",
publisher = "Walter De Gruyter Gmbh, Berlin",
journal = "Biomedical Engineering-Biomedizinische Technik",
title = "Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction",
pages = "505-491",
number = "4",
volume = "65",
doi = "10.1515/bmt-2019-0218"
}
Micić, M., Antonijević, Đ., Milutinović-Smiljanić, S., Trisić, D., Colović, B., Kosanović, D., Prokić, B., Vasić, J., Zivković, S., Milašin, J., Danilović, V., Đurić, M.,& Jokanović, V.. (2020). Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction. in Biomedical Engineering-Biomedizinische Technik
Walter De Gruyter Gmbh, Berlin., 65(4), 491-505.
https://doi.org/10.1515/bmt-2019-0218
Micić M, Antonijević Đ, Milutinović-Smiljanić S, Trisić D, Colović B, Kosanović D, Prokić B, Vasić J, Zivković S, Milašin J, Danilović V, Đurić M, Jokanović V. Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction. in Biomedical Engineering-Biomedizinische Technik. 2020;65(4):491-505.
doi:10.1515/bmt-2019-0218 .
Micić, Milutin, Antonijević, Đorđe, Milutinović-Smiljanić, Sanja, Trisić, Dijana, Colović, Božana, Kosanović, Dejana, Prokić, Bogomir, Vasić, Jugoslav, Zivković, Slavoljub, Milašin, Jelena, Danilović, Vesna, Đurić, Marija, Jokanović, Vukoman, "Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction" in Biomedical Engineering-Biomedizinische Technik, 65, no. 4 (2020):491-505,
https://doi.org/10.1515/bmt-2019-0218 . .
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