Filipović-Vignjević, Svetlana

Link to this page

Authority KeyName Variants
orcid::0000-0002-1373-6872
  • Filipović-Vignjević, Svetlana (4)
Projects

Author's Bibliography

Retrospective Analysis of Six Years of Acute Flaccid Paralysis Surveillance and Polio Vaccine Coverage Reported by Italy, Serbia, Bosnia and Herzegovina, Montenegro, Bulgaria, Kosovo, Albania, North Macedonia, Malta, and Greece

Fontana, Stefano; Buttinelli, Gabriele; Fiore, Stefano; Amato, Concetta; Pataracchia, Marco; Kota, Majlinda; Aćimović, Jela; Blažević, Mia; Mulaomerović, Mirsada; Nikolaeva-Glomb, Lubomira; Mentis, Andreas; Voulgari-Kokota, Androniki; Gashi, Luljeta; Kaçaniku-Gunga, Pranvera; Barbara, Christopher; Melillo, Jackie; Protic, Jelena; Filipović-Vignjević, Svetlana; O’Connor, Patrick M.; D’Alberto, Alessandra; Orioli, Riccardo; Siddu, Andrea; Saxentoff, Eugene; Stefanelli, Paola

(MDPI, 2022)

TY  - JOUR
AU  - Fontana, Stefano
AU  - Buttinelli, Gabriele
AU  - Fiore, Stefano
AU  - Amato, Concetta
AU  - Pataracchia, Marco
AU  - Kota, Majlinda
AU  - Aćimović, Jela
AU  - Blažević, Mia
AU  - Mulaomerović, Mirsada
AU  - Nikolaeva-Glomb, Lubomira
AU  - Mentis, Andreas
AU  - Voulgari-Kokota, Androniki
AU  - Gashi, Luljeta
AU  - Kaçaniku-Gunga, Pranvera
AU  - Barbara, Christopher
AU  - Melillo, Jackie
AU  - Protic, Jelena
AU  - Filipović-Vignjević, Svetlana
AU  - O’Connor, Patrick M.
AU  - D’Alberto, Alessandra
AU  - Orioli, Riccardo
AU  - Siddu, Andrea
AU  - Saxentoff, Eugene
AU  - Stefanelli, Paola
PY  - 2022
UR  - http://intor.torlakinstitut.com/handle/123456789/618
AB  - Here we analyzed six years of acute flaccid paralysis (AFP) surveillance, from 2015 to 2020, of 10 countries linked to the WHO Regional Reference Laboratory, at the Istituto Superiore di Sanità, Italy. The analysis also comprises the polio vaccine coverage available (2015–2019) and enterovirus (EV) identification and typing data. Centralized Information System for Infectious Diseases and Laboratory Data Management System databases were used to obtain data on AFP indicators and laboratory performance and countries’ vaccine coverage from 2015 to 2019. EV isolation, identification, and typing were performed by each country according to WHO protocols. Overall, a general AFP underreporting was observed. Non-Polio Enterovirus (NPEV) typing showed a high heterogeneity: over the years, several genotypes of coxsackievirus and echovirus have been identified. The polio vaccine coverage, for the data available, differs among countries. This evaluation allows for the collection, for the first time, of data from the countries of the Balkan area regarding AFP surveillance and polio vaccine coverage. The need, for some countries, to enhance the surveillance systems and to promote the polio vaccine uptake, in order to maintain the polio-free status, is evident.
PB  - MDPI
T2  - Vaccines
T1  - Retrospective Analysis of Six Years of Acute Flaccid Paralysis Surveillance and Polio Vaccine Coverage Reported by Italy, Serbia, Bosnia and Herzegovina, Montenegro, Bulgaria, Kosovo, Albania, North Macedonia, Malta, and Greece
IS  - 1
SP  - 44
VL  - 10
DO  - 10.3390/vaccines10010044
ER  - 
@article{
author = "Fontana, Stefano and Buttinelli, Gabriele and Fiore, Stefano and Amato, Concetta and Pataracchia, Marco and Kota, Majlinda and Aćimović, Jela and Blažević, Mia and Mulaomerović, Mirsada and Nikolaeva-Glomb, Lubomira and Mentis, Andreas and Voulgari-Kokota, Androniki and Gashi, Luljeta and Kaçaniku-Gunga, Pranvera and Barbara, Christopher and Melillo, Jackie and Protic, Jelena and Filipović-Vignjević, Svetlana and O’Connor, Patrick M. and D’Alberto, Alessandra and Orioli, Riccardo and Siddu, Andrea and Saxentoff, Eugene and Stefanelli, Paola",
year = "2022",
abstract = "Here we analyzed six years of acute flaccid paralysis (AFP) surveillance, from 2015 to 2020, of 10 countries linked to the WHO Regional Reference Laboratory, at the Istituto Superiore di Sanità, Italy. The analysis also comprises the polio vaccine coverage available (2015–2019) and enterovirus (EV) identification and typing data. Centralized Information System for Infectious Diseases and Laboratory Data Management System databases were used to obtain data on AFP indicators and laboratory performance and countries’ vaccine coverage from 2015 to 2019. EV isolation, identification, and typing were performed by each country according to WHO protocols. Overall, a general AFP underreporting was observed. Non-Polio Enterovirus (NPEV) typing showed a high heterogeneity: over the years, several genotypes of coxsackievirus and echovirus have been identified. The polio vaccine coverage, for the data available, differs among countries. This evaluation allows for the collection, for the first time, of data from the countries of the Balkan area regarding AFP surveillance and polio vaccine coverage. The need, for some countries, to enhance the surveillance systems and to promote the polio vaccine uptake, in order to maintain the polio-free status, is evident.",
publisher = "MDPI",
journal = "Vaccines",
title = "Retrospective Analysis of Six Years of Acute Flaccid Paralysis Surveillance and Polio Vaccine Coverage Reported by Italy, Serbia, Bosnia and Herzegovina, Montenegro, Bulgaria, Kosovo, Albania, North Macedonia, Malta, and Greece",
number = "1",
pages = "44",
volume = "10",
doi = "10.3390/vaccines10010044"
}
Fontana, S., Buttinelli, G., Fiore, S., Amato, C., Pataracchia, M., Kota, M., Aćimović, J., Blažević, M., Mulaomerović, M., Nikolaeva-Glomb, L., Mentis, A., Voulgari-Kokota, A., Gashi, L., Kaçaniku-Gunga, P., Barbara, C., Melillo, J., Protic, J., Filipović-Vignjević, S., O’Connor, P. M., D’Alberto, A., Orioli, R., Siddu, A., Saxentoff, E.,& Stefanelli, P.. (2022). Retrospective Analysis of Six Years of Acute Flaccid Paralysis Surveillance and Polio Vaccine Coverage Reported by Italy, Serbia, Bosnia and Herzegovina, Montenegro, Bulgaria, Kosovo, Albania, North Macedonia, Malta, and Greece. in Vaccines
MDPI., 10(1), 44.
https://doi.org/10.3390/vaccines10010044
Fontana S, Buttinelli G, Fiore S, Amato C, Pataracchia M, Kota M, Aćimović J, Blažević M, Mulaomerović M, Nikolaeva-Glomb L, Mentis A, Voulgari-Kokota A, Gashi L, Kaçaniku-Gunga P, Barbara C, Melillo J, Protic J, Filipović-Vignjević S, O’Connor PM, D’Alberto A, Orioli R, Siddu A, Saxentoff E, Stefanelli P. Retrospective Analysis of Six Years of Acute Flaccid Paralysis Surveillance and Polio Vaccine Coverage Reported by Italy, Serbia, Bosnia and Herzegovina, Montenegro, Bulgaria, Kosovo, Albania, North Macedonia, Malta, and Greece. in Vaccines. 2022;10(1):44.
doi:10.3390/vaccines10010044 .
Fontana, Stefano, Buttinelli, Gabriele, Fiore, Stefano, Amato, Concetta, Pataracchia, Marco, Kota, Majlinda, Aćimović, Jela, Blažević, Mia, Mulaomerović, Mirsada, Nikolaeva-Glomb, Lubomira, Mentis, Andreas, Voulgari-Kokota, Androniki, Gashi, Luljeta, Kaçaniku-Gunga, Pranvera, Barbara, Christopher, Melillo, Jackie, Protic, Jelena, Filipović-Vignjević, Svetlana, O’Connor, Patrick M., D’Alberto, Alessandra, Orioli, Riccardo, Siddu, Andrea, Saxentoff, Eugene, Stefanelli, Paola, "Retrospective Analysis of Six Years of Acute Flaccid Paralysis Surveillance and Polio Vaccine Coverage Reported by Italy, Serbia, Bosnia and Herzegovina, Montenegro, Bulgaria, Kosovo, Albania, North Macedonia, Malta, and Greece" in Vaccines, 10, no. 1 (2022):44,
https://doi.org/10.3390/vaccines10010044 . .
1
1
1

Rise in 2017-2018 measles morbidity in Serbia and northwest Russia

Stoiljković, Vera; Bichurina, M.A.; Lavrentieva, I.N.; Filipović-Vignjević, Svetlana; Bancević, M.D.; Zheleznova, N.V.; Antipova, A.Yu

(Sankt-Petersburg-Niiem Imeni Pastera, St Petersburg, 2020)

TY  - JOUR
AU  - Stoiljković, Vera
AU  - Bichurina, M.A.
AU  - Lavrentieva, I.N.
AU  - Filipović-Vignjević, Svetlana
AU  - Bancević, M.D.
AU  - Zheleznova, N.V.
AU  - Antipova, A.Yu
PY  - 2020
UR  - http://intor.torlakinstitut.com/handle/123456789/550
AB  - In 2017, the WHO registered 23,927 measles cases in 44 out of 53 countries in the European region. In 2018, measles incidence rate increased up to 82,599 cases registered in 48 countries of the region, with a large number of measles-associated deaths. Overall, 72 measles fatalities were registered in 10 European countries, including Serbia (15 cases). Aim of the study: to characterize 2017-2018 epidemiological upsurge of measles incidence rate observed in the Republic of Serbia (RS) and the Northwestern Federal District (NWFD) of the Russian Federation. Materials and methods. During the 2017-2018 season, 944 serum samples were collected from patients with measles, rubella, or exanthematous diseases in the NWFD and tested in the Laboratory of Virology at the St. Petersburg Regional Centre for Measles Surveillance (SPbRC). In 2017-2018, 2,946 serum samples from the Republic of Serbia were analyzed in the SPbRC by using ELISA with IgM measles test system (Vector-Best, Russia; or Siemens, Germany). Urine and swab samples were examined by RT-PCR and used for isolation and genotyping of measles viruses. Results. From 2017 to 2018, 5,798 measles cases were registered in the RS, among which 2,946 were laboratory-confirmed (serological testing and/or PCR). Unvaccinated subjects or those with unknown vaccination status accounted for majority of the cases. Children under 5 years of age and adults aged 30 years and over dominated among measles patients. During this season, 15 deaths were reported. Several genotypes of measles virus circulated in the RS, e.g. B3 Dublin, D8 Gir Somnath, and D8 Herborn. In 2018, 109 measles cases were recorded in the NWFD, 5 of which were imported from abroad. Among patients, adults comprised 64.2%, wherein 74.3% were covered by unvaccinated subjects or those with unknown vaccination status. Rise in measles incidence rate linked to multiple importations of various measles virus genotypes: B3 Kabul; B3 Dublin; D8 Frankfurt; D8 Cambridge; and D8 Gir Somnath.
PB  - Sankt-Petersburg-Niiem Imeni Pastera, St Petersburg
T2  - Infektsiya I Immunitet
T1  - Rise in 2017-2018 measles morbidity in Serbia and northwest Russia
EP  - 734
IS  - 4
SP  - 729
VL  - 10
DO  - 10.15789/2220-7619-RIM-1342
UR  - conv_486
ER  - 
@article{
author = "Stoiljković, Vera and Bichurina, M.A. and Lavrentieva, I.N. and Filipović-Vignjević, Svetlana and Bancević, M.D. and Zheleznova, N.V. and Antipova, A.Yu",
year = "2020",
abstract = "In 2017, the WHO registered 23,927 measles cases in 44 out of 53 countries in the European region. In 2018, measles incidence rate increased up to 82,599 cases registered in 48 countries of the region, with a large number of measles-associated deaths. Overall, 72 measles fatalities were registered in 10 European countries, including Serbia (15 cases). Aim of the study: to characterize 2017-2018 epidemiological upsurge of measles incidence rate observed in the Republic of Serbia (RS) and the Northwestern Federal District (NWFD) of the Russian Federation. Materials and methods. During the 2017-2018 season, 944 serum samples were collected from patients with measles, rubella, or exanthematous diseases in the NWFD and tested in the Laboratory of Virology at the St. Petersburg Regional Centre for Measles Surveillance (SPbRC). In 2017-2018, 2,946 serum samples from the Republic of Serbia were analyzed in the SPbRC by using ELISA with IgM measles test system (Vector-Best, Russia; or Siemens, Germany). Urine and swab samples were examined by RT-PCR and used for isolation and genotyping of measles viruses. Results. From 2017 to 2018, 5,798 measles cases were registered in the RS, among which 2,946 were laboratory-confirmed (serological testing and/or PCR). Unvaccinated subjects or those with unknown vaccination status accounted for majority of the cases. Children under 5 years of age and adults aged 30 years and over dominated among measles patients. During this season, 15 deaths were reported. Several genotypes of measles virus circulated in the RS, e.g. B3 Dublin, D8 Gir Somnath, and D8 Herborn. In 2018, 109 measles cases were recorded in the NWFD, 5 of which were imported from abroad. Among patients, adults comprised 64.2%, wherein 74.3% were covered by unvaccinated subjects or those with unknown vaccination status. Rise in measles incidence rate linked to multiple importations of various measles virus genotypes: B3 Kabul; B3 Dublin; D8 Frankfurt; D8 Cambridge; and D8 Gir Somnath.",
publisher = "Sankt-Petersburg-Niiem Imeni Pastera, St Petersburg",
journal = "Infektsiya I Immunitet",
title = "Rise in 2017-2018 measles morbidity in Serbia and northwest Russia",
pages = "734-729",
number = "4",
volume = "10",
doi = "10.15789/2220-7619-RIM-1342",
url = "conv_486"
}
Stoiljković, V., Bichurina, M.A., Lavrentieva, I.N., Filipović-Vignjević, S., Bancević, M.D., Zheleznova, N.V.,& Antipova, A.Yu. (2020). Rise in 2017-2018 measles morbidity in Serbia and northwest Russia. in Infektsiya I Immunitet
Sankt-Petersburg-Niiem Imeni Pastera, St Petersburg., 10(4), 729-734.
https://doi.org/10.15789/2220-7619-RIM-1342
conv_486
Stoiljković V, Bichurina M, Lavrentieva I, Filipović-Vignjević S, Bancević M, Zheleznova N, Antipova A. Rise in 2017-2018 measles morbidity in Serbia and northwest Russia. in Infektsiya I Immunitet. 2020;10(4):729-734.
doi:10.15789/2220-7619-RIM-1342
conv_486 .
Stoiljković, Vera, Bichurina, M.A., Lavrentieva, I.N., Filipović-Vignjević, Svetlana, Bancević, M.D., Zheleznova, N.V., Antipova, A.Yu, "Rise in 2017-2018 measles morbidity in Serbia and northwest Russia" in Infektsiya I Immunitet, 10, no. 4 (2020):729-734,
https://doi.org/10.15789/2220-7619-RIM-1342 .,
conv_486 .
2
2

Implementation of the One Health approach to fight arbovirus infections in the Mediterranean and Black Sea Region: Assessing integrated surveillance in Serbia, Tunisia and Georgia

Dente, Maria Grazia; Riccardo, Flavia; Bolici, Francesco; Colella, Nello Augusto; Jovanović, Verica; Drakulović, Mitra; Vasić, Milena; Mamlouk, Habiba; Maazaoui, Latifa; Bejaoui, Mondher; Zakhashvili, Khatuna; Kalandadze, Irine; Imnadze, Paata; Declich, Silvia; Knjeginić, Vesna; Stojković, Borka; Labus, Tatjana; Milicević, Vesna; Veljović, Ljubiša; Maksimović-Zorić, Jelena; Stoiljković, Vera; Filipović-Vignjević, Svetlana; Protić, Jelena; Zgomba, Marija; Petrić, Dusan; Despot, Dragana; Pesić, Branislav; Serović, Katarina; Aleksić, Ivan; Đurić, Ivana; Ilić, Dragan; Vrga, Svetlana; Pavlović, Ljiljana; Plavsa, Dragana; Grego, Edita; Harabech, Kaouther; Ben Alaya, Nissaf; Bougatef, Souha; Triki, Henda; Bouattour, Ali; Rebhi, Mohamed; Daaboub, Jabeur; Somai, Lamia; Zerlli, Malek; Zerlli, Malek; Oukaili, Kaouther; Ammar, Heni Haj; Sghaier, Chedia; Fatnassi, Naouel; Kalthoum, Sana; Dhaouadi, Anissa; Ben Youness, Abdelhak; Mahale, Issam; Marzouk, Mongi; Ben Bdira, Sassi; Grira, Samia; Ayadi, Sonia; Mastouri, Maha; Faten, Allad; Abdelkader, Ben; Chakhunashvili, Giorgi; Babuadze, Giorgi; Mamuchishvili, Nana; Chanturia, Gvantsa; Adeishvili, Ekaterine; Avaliani, Lasha; Ninidze, Lena; Kartskhia, Natia; Gulbani, Ana; Kokhreidze, Maka; Donduashvili, Marina; Kekelidze, Anna

(Wiley, Hoboken, 2019)

TY  - JOUR
AU  - Dente, Maria Grazia
AU  - Riccardo, Flavia
AU  - Bolici, Francesco
AU  - Colella, Nello Augusto
AU  - Jovanović, Verica
AU  - Drakulović, Mitra
AU  - Vasić, Milena
AU  - Mamlouk, Habiba
AU  - Maazaoui, Latifa
AU  - Bejaoui, Mondher
AU  - Zakhashvili, Khatuna
AU  - Kalandadze, Irine
AU  - Imnadze, Paata
AU  - Declich, Silvia
AU  - Knjeginić, Vesna
AU  - Stojković, Borka
AU  - Labus, Tatjana
AU  - Milicević, Vesna
AU  - Veljović, Ljubiša
AU  - Maksimović-Zorić, Jelena
AU  - Stoiljković, Vera
AU  - Filipović-Vignjević, Svetlana
AU  - Protić, Jelena
AU  - Zgomba, Marija
AU  - Petrić, Dusan
AU  - Despot, Dragana
AU  - Pesić, Branislav
AU  - Serović, Katarina
AU  - Aleksić, Ivan
AU  - Đurić, Ivana
AU  - Ilić, Dragan
AU  - Vrga, Svetlana
AU  - Pavlović, Ljiljana
AU  - Plavsa, Dragana
AU  - Grego, Edita
AU  - Harabech, Kaouther
AU  - Ben Alaya, Nissaf
AU  - Bougatef, Souha
AU  - Triki, Henda
AU  - Bouattour, Ali
AU  - Rebhi, Mohamed
AU  - Daaboub, Jabeur
AU  - Somai, Lamia
AU  - Zerlli, Malek
AU  - Zerlli, Malek
AU  - Oukaili, Kaouther
AU  - Ammar, Heni Haj
AU  - Sghaier, Chedia
AU  - Fatnassi, Naouel
AU  - Kalthoum, Sana
AU  - Dhaouadi, Anissa
AU  - Ben Youness, Abdelhak
AU  - Mahale, Issam
AU  - Marzouk, Mongi
AU  - Ben Bdira, Sassi
AU  - Grira, Samia
AU  - Ayadi, Sonia
AU  - Mastouri, Maha
AU  - Faten, Allad
AU  - Abdelkader, Ben
AU  - Chakhunashvili, Giorgi
AU  - Babuadze, Giorgi
AU  - Mamuchishvili, Nana
AU  - Chanturia, Gvantsa
AU  - Adeishvili, Ekaterine
AU  - Avaliani, Lasha
AU  - Ninidze, Lena
AU  - Kartskhia, Natia
AU  - Gulbani, Ana
AU  - Kokhreidze, Maka
AU  - Donduashvili, Marina
AU  - Kekelidze, Anna
PY  - 2019
UR  - http://intor.torlakinstitut.com/handle/123456789/535
AB  - Background In the Mediterranean and Black Sea Region, arbovirus infections are emerging infectious diseases. Their surveillance can benefit from one health inter-sectoral collaboration; however, no standardized methodology exists to study One Health surveillance. Methods We designed a situation analysis study to document how integration of laboratory/clinical human, animal and entomological surveillance of arboviruses was being implemented in the Region. We applied a framework designed to assess three levels of integration: policy/institutional, data collection/data analysis and dissemination. We tested the use of Business Process Modelling Notation (BPMN) to graphically present evidence of inter-sectoral integration. Results Serbia, Tunisia and Georgia participated in the study. West Nile Virus surveillance was analysed in Serbia and Tunisia, Crimea-Congo Haemorrhagic Fever surveillance in Georgia. Our framework enabled a standardized analysis of One Health surveillance integration, and BPMN was easily understandable and conducive to detailed discussions among different actors/institutions. In all countries, we observed integration across sectors and levels except in data collection and data analysis. Data collection was interoperable only in Georgia without integrated analysis. In all countries, surveillance was mainly oriented towards outbreak response, triggered by an index human case. Discussion The three surveillance systems we observed prove that integrated surveillance can be operationalized with a diverse spectrum of options. However, in all countries, the integrated use of data for early warning and inter-sectoral priority setting is pioneeristic. We also noted that early warning before human case occurrence is recurrently not operationally prioritized.
PB  - Wiley, Hoboken
T2  - Zoonoses and Public Health
T1  - Implementation of the One Health approach to fight arbovirus infections in the Mediterranean and Black Sea Region: Assessing integrated surveillance in Serbia, Tunisia and Georgia
EP  - 287
IS  - 3
SP  - 276
VL  - 66
DO  - 10.1111/zph.12562
UR  - conv_452
ER  - 
@article{
author = "Dente, Maria Grazia and Riccardo, Flavia and Bolici, Francesco and Colella, Nello Augusto and Jovanović, Verica and Drakulović, Mitra and Vasić, Milena and Mamlouk, Habiba and Maazaoui, Latifa and Bejaoui, Mondher and Zakhashvili, Khatuna and Kalandadze, Irine and Imnadze, Paata and Declich, Silvia and Knjeginić, Vesna and Stojković, Borka and Labus, Tatjana and Milicević, Vesna and Veljović, Ljubiša and Maksimović-Zorić, Jelena and Stoiljković, Vera and Filipović-Vignjević, Svetlana and Protić, Jelena and Zgomba, Marija and Petrić, Dusan and Despot, Dragana and Pesić, Branislav and Serović, Katarina and Aleksić, Ivan and Đurić, Ivana and Ilić, Dragan and Vrga, Svetlana and Pavlović, Ljiljana and Plavsa, Dragana and Grego, Edita and Harabech, Kaouther and Ben Alaya, Nissaf and Bougatef, Souha and Triki, Henda and Bouattour, Ali and Rebhi, Mohamed and Daaboub, Jabeur and Somai, Lamia and Zerlli, Malek and Zerlli, Malek and Oukaili, Kaouther and Ammar, Heni Haj and Sghaier, Chedia and Fatnassi, Naouel and Kalthoum, Sana and Dhaouadi, Anissa and Ben Youness, Abdelhak and Mahale, Issam and Marzouk, Mongi and Ben Bdira, Sassi and Grira, Samia and Ayadi, Sonia and Mastouri, Maha and Faten, Allad and Abdelkader, Ben and Chakhunashvili, Giorgi and Babuadze, Giorgi and Mamuchishvili, Nana and Chanturia, Gvantsa and Adeishvili, Ekaterine and Avaliani, Lasha and Ninidze, Lena and Kartskhia, Natia and Gulbani, Ana and Kokhreidze, Maka and Donduashvili, Marina and Kekelidze, Anna",
year = "2019",
abstract = "Background In the Mediterranean and Black Sea Region, arbovirus infections are emerging infectious diseases. Their surveillance can benefit from one health inter-sectoral collaboration; however, no standardized methodology exists to study One Health surveillance. Methods We designed a situation analysis study to document how integration of laboratory/clinical human, animal and entomological surveillance of arboviruses was being implemented in the Region. We applied a framework designed to assess three levels of integration: policy/institutional, data collection/data analysis and dissemination. We tested the use of Business Process Modelling Notation (BPMN) to graphically present evidence of inter-sectoral integration. Results Serbia, Tunisia and Georgia participated in the study. West Nile Virus surveillance was analysed in Serbia and Tunisia, Crimea-Congo Haemorrhagic Fever surveillance in Georgia. Our framework enabled a standardized analysis of One Health surveillance integration, and BPMN was easily understandable and conducive to detailed discussions among different actors/institutions. In all countries, we observed integration across sectors and levels except in data collection and data analysis. Data collection was interoperable only in Georgia without integrated analysis. In all countries, surveillance was mainly oriented towards outbreak response, triggered by an index human case. Discussion The three surveillance systems we observed prove that integrated surveillance can be operationalized with a diverse spectrum of options. However, in all countries, the integrated use of data for early warning and inter-sectoral priority setting is pioneeristic. We also noted that early warning before human case occurrence is recurrently not operationally prioritized.",
publisher = "Wiley, Hoboken",
journal = "Zoonoses and Public Health",
title = "Implementation of the One Health approach to fight arbovirus infections in the Mediterranean and Black Sea Region: Assessing integrated surveillance in Serbia, Tunisia and Georgia",
pages = "287-276",
number = "3",
volume = "66",
doi = "10.1111/zph.12562",
url = "conv_452"
}
Dente, M. G., Riccardo, F., Bolici, F., Colella, N. A., Jovanović, V., Drakulović, M., Vasić, M., Mamlouk, H., Maazaoui, L., Bejaoui, M., Zakhashvili, K., Kalandadze, I., Imnadze, P., Declich, S., Knjeginić, V., Stojković, B., Labus, T., Milicević, V., Veljović, L., Maksimović-Zorić, J., Stoiljković, V., Filipović-Vignjević, S., Protić, J., Zgomba, M., Petrić, D., Despot, D., Pesić, B., Serović, K., Aleksić, I., Đurić, I., Ilić, D., Vrga, S., Pavlović, L., Plavsa, D., Grego, E., Harabech, K., Ben Alaya, N., Bougatef, S., Triki, H., Bouattour, A., Rebhi, M., Daaboub, J., Somai, L., Zerlli, M., Zerlli, M., Oukaili, K., Ammar, H. H., Sghaier, C., Fatnassi, N., Kalthoum, S., Dhaouadi, A., Ben Youness, A., Mahale, I., Marzouk, M., Ben Bdira, S., Grira, S., Ayadi, S., Mastouri, M., Faten, A., Abdelkader, B., Chakhunashvili, G., Babuadze, G., Mamuchishvili, N., Chanturia, G., Adeishvili, E., Avaliani, L., Ninidze, L., Kartskhia, N., Gulbani, A., Kokhreidze, M., Donduashvili, M.,& Kekelidze, A.. (2019). Implementation of the One Health approach to fight arbovirus infections in the Mediterranean and Black Sea Region: Assessing integrated surveillance in Serbia, Tunisia and Georgia. in Zoonoses and Public Health
Wiley, Hoboken., 66(3), 276-287.
https://doi.org/10.1111/zph.12562
conv_452
Dente MG, Riccardo F, Bolici F, Colella NA, Jovanović V, Drakulović M, Vasić M, Mamlouk H, Maazaoui L, Bejaoui M, Zakhashvili K, Kalandadze I, Imnadze P, Declich S, Knjeginić V, Stojković B, Labus T, Milicević V, Veljović L, Maksimović-Zorić J, Stoiljković V, Filipović-Vignjević S, Protić J, Zgomba M, Petrić D, Despot D, Pesić B, Serović K, Aleksić I, Đurić I, Ilić D, Vrga S, Pavlović L, Plavsa D, Grego E, Harabech K, Ben Alaya N, Bougatef S, Triki H, Bouattour A, Rebhi M, Daaboub J, Somai L, Zerlli M, Zerlli M, Oukaili K, Ammar HH, Sghaier C, Fatnassi N, Kalthoum S, Dhaouadi A, Ben Youness A, Mahale I, Marzouk M, Ben Bdira S, Grira S, Ayadi S, Mastouri M, Faten A, Abdelkader B, Chakhunashvili G, Babuadze G, Mamuchishvili N, Chanturia G, Adeishvili E, Avaliani L, Ninidze L, Kartskhia N, Gulbani A, Kokhreidze M, Donduashvili M, Kekelidze A. Implementation of the One Health approach to fight arbovirus infections in the Mediterranean and Black Sea Region: Assessing integrated surveillance in Serbia, Tunisia and Georgia. in Zoonoses and Public Health. 2019;66(3):276-287.
doi:10.1111/zph.12562
conv_452 .
Dente, Maria Grazia, Riccardo, Flavia, Bolici, Francesco, Colella, Nello Augusto, Jovanović, Verica, Drakulović, Mitra, Vasić, Milena, Mamlouk, Habiba, Maazaoui, Latifa, Bejaoui, Mondher, Zakhashvili, Khatuna, Kalandadze, Irine, Imnadze, Paata, Declich, Silvia, Knjeginić, Vesna, Stojković, Borka, Labus, Tatjana, Milicević, Vesna, Veljović, Ljubiša, Maksimović-Zorić, Jelena, Stoiljković, Vera, Filipović-Vignjević, Svetlana, Protić, Jelena, Zgomba, Marija, Petrić, Dusan, Despot, Dragana, Pesić, Branislav, Serović, Katarina, Aleksić, Ivan, Đurić, Ivana, Ilić, Dragan, Vrga, Svetlana, Pavlović, Ljiljana, Plavsa, Dragana, Grego, Edita, Harabech, Kaouther, Ben Alaya, Nissaf, Bougatef, Souha, Triki, Henda, Bouattour, Ali, Rebhi, Mohamed, Daaboub, Jabeur, Somai, Lamia, Zerlli, Malek, Zerlli, Malek, Oukaili, Kaouther, Ammar, Heni Haj, Sghaier, Chedia, Fatnassi, Naouel, Kalthoum, Sana, Dhaouadi, Anissa, Ben Youness, Abdelhak, Mahale, Issam, Marzouk, Mongi, Ben Bdira, Sassi, Grira, Samia, Ayadi, Sonia, Mastouri, Maha, Faten, Allad, Abdelkader, Ben, Chakhunashvili, Giorgi, Babuadze, Giorgi, Mamuchishvili, Nana, Chanturia, Gvantsa, Adeishvili, Ekaterine, Avaliani, Lasha, Ninidze, Lena, Kartskhia, Natia, Gulbani, Ana, Kokhreidze, Maka, Donduashvili, Marina, Kekelidze, Anna, "Implementation of the One Health approach to fight arbovirus infections in the Mediterranean and Black Sea Region: Assessing integrated surveillance in Serbia, Tunisia and Georgia" in Zoonoses and Public Health, 66, no. 3 (2019):276-287,
https://doi.org/10.1111/zph.12562 .,
conv_452 .
1
17
11
16

Safety and immunogenicity of a seasonal trivalent inactivated split influenza vaccine: a phase I randomized clinical trial in healthy Serbian adults

Stevanović, Goran; Lavadinović, Lidija; Filipović-Vignjević, Svetlana; Holt, Renee; Ilić, Katarina; Scorza, Francesco Berlanda; Sparrow, Erin; Stoiljković, Vera; Torelli, Guido; Madenwald, Tamra; Socquet, Muriel; Barac, Aleksandra; Ilieva-Borisova, Yordanka; Pelemiš, Mijomir; Flores, Jorge

(Taylor & Francis Inc, Philadelphia, 2018)

TY  - JOUR
AU  - Stevanović, Goran
AU  - Lavadinović, Lidija
AU  - Filipović-Vignjević, Svetlana
AU  - Holt, Renee
AU  - Ilić, Katarina
AU  - Scorza, Francesco Berlanda
AU  - Sparrow, Erin
AU  - Stoiljković, Vera
AU  - Torelli, Guido
AU  - Madenwald, Tamra
AU  - Socquet, Muriel
AU  - Barac, Aleksandra
AU  - Ilieva-Borisova, Yordanka
AU  - Pelemiš, Mijomir
AU  - Flores, Jorge
PY  - 2018
UR  - http://intor.torlakinstitut.com/handle/123456789/517
AB  - This study was a phase I double-blind, randomized, placebo-controlled trial to evaluate the safety and immunogenicity of a Serbian-produced seasonal trivalent split, inactivated influenza vaccine in healthy adults. The vaccine was manufactured in eggs by the Torlak Institute of Virology, Vaccines and Sera, Belgrade, Serbia and contained A/H1N1, A/H3N2 and B viruses. The clinical trial took place at the Clinical Center of Serbia in Belgrade. Sixty healthy volunteers, aged 18-45years, were enrolled in the trial. On the day of immunization, volunteers were randomly assigned to receive either a single dose of the trivalent seasonal influenza vaccine (15g of hemagglutinin per strain) or placebo (phosphate-buffered saline). Subjects were monitored for adverse events through a clinical history and physical examination, and blood was taken for testing at screening and on day 8 to assess vaccine safety. Serum samples obtained before and 21days after immunization were tested for influenza antibody titers using hemagglutination-inhibition (HAI) and microneutralization (MN) tests. No serious adverse events were reported. Pain and tenderness at the injection site were the most commonly reported symptoms in both vaccine and placebo groups. Overall, serum HAI responses of fourfold or greater magnitude were observed to H1, H3, and B antigen in 80%, 75%, and 70% of subjects, respectively. Seroprotection rates as measured by HAI were also high (100%, 100% and 86.67%, respectively, for H1, H3 and B). Thus, Torlak's seasonal trivalent influenza vaccine was not associated with adverse events, was well-tolerated and immunogenic. It should be further evaluated in clinical trials to provide sufficient safety and immunogenicity data for licensing in Serbia.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Human Vaccines & Immunotherapeutics
T1  - Safety and immunogenicity of a seasonal trivalent inactivated split influenza vaccine: a phase I randomized clinical trial in healthy Serbian adults
EP  - 586
IS  - 3
SP  - 579
VL  - 14
DO  - 10.1080/21645515.2017.1415683
UR  - conv_427
ER  - 
@article{
author = "Stevanović, Goran and Lavadinović, Lidija and Filipović-Vignjević, Svetlana and Holt, Renee and Ilić, Katarina and Scorza, Francesco Berlanda and Sparrow, Erin and Stoiljković, Vera and Torelli, Guido and Madenwald, Tamra and Socquet, Muriel and Barac, Aleksandra and Ilieva-Borisova, Yordanka and Pelemiš, Mijomir and Flores, Jorge",
year = "2018",
abstract = "This study was a phase I double-blind, randomized, placebo-controlled trial to evaluate the safety and immunogenicity of a Serbian-produced seasonal trivalent split, inactivated influenza vaccine in healthy adults. The vaccine was manufactured in eggs by the Torlak Institute of Virology, Vaccines and Sera, Belgrade, Serbia and contained A/H1N1, A/H3N2 and B viruses. The clinical trial took place at the Clinical Center of Serbia in Belgrade. Sixty healthy volunteers, aged 18-45years, were enrolled in the trial. On the day of immunization, volunteers were randomly assigned to receive either a single dose of the trivalent seasonal influenza vaccine (15g of hemagglutinin per strain) or placebo (phosphate-buffered saline). Subjects were monitored for adverse events through a clinical history and physical examination, and blood was taken for testing at screening and on day 8 to assess vaccine safety. Serum samples obtained before and 21days after immunization were tested for influenza antibody titers using hemagglutination-inhibition (HAI) and microneutralization (MN) tests. No serious adverse events were reported. Pain and tenderness at the injection site were the most commonly reported symptoms in both vaccine and placebo groups. Overall, serum HAI responses of fourfold or greater magnitude were observed to H1, H3, and B antigen in 80%, 75%, and 70% of subjects, respectively. Seroprotection rates as measured by HAI were also high (100%, 100% and 86.67%, respectively, for H1, H3 and B). Thus, Torlak's seasonal trivalent influenza vaccine was not associated with adverse events, was well-tolerated and immunogenic. It should be further evaluated in clinical trials to provide sufficient safety and immunogenicity data for licensing in Serbia.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Human Vaccines & Immunotherapeutics",
title = "Safety and immunogenicity of a seasonal trivalent inactivated split influenza vaccine: a phase I randomized clinical trial in healthy Serbian adults",
pages = "586-579",
number = "3",
volume = "14",
doi = "10.1080/21645515.2017.1415683",
url = "conv_427"
}
Stevanović, G., Lavadinović, L., Filipović-Vignjević, S., Holt, R., Ilić, K., Scorza, F. B., Sparrow, E., Stoiljković, V., Torelli, G., Madenwald, T., Socquet, M., Barac, A., Ilieva-Borisova, Y., Pelemiš, M.,& Flores, J.. (2018). Safety and immunogenicity of a seasonal trivalent inactivated split influenza vaccine: a phase I randomized clinical trial in healthy Serbian adults. in Human Vaccines & Immunotherapeutics
Taylor & Francis Inc, Philadelphia., 14(3), 579-586.
https://doi.org/10.1080/21645515.2017.1415683
conv_427
Stevanović G, Lavadinović L, Filipović-Vignjević S, Holt R, Ilić K, Scorza FB, Sparrow E, Stoiljković V, Torelli G, Madenwald T, Socquet M, Barac A, Ilieva-Borisova Y, Pelemiš M, Flores J. Safety and immunogenicity of a seasonal trivalent inactivated split influenza vaccine: a phase I randomized clinical trial in healthy Serbian adults. in Human Vaccines & Immunotherapeutics. 2018;14(3):579-586.
doi:10.1080/21645515.2017.1415683
conv_427 .
Stevanović, Goran, Lavadinović, Lidija, Filipović-Vignjević, Svetlana, Holt, Renee, Ilić, Katarina, Scorza, Francesco Berlanda, Sparrow, Erin, Stoiljković, Vera, Torelli, Guido, Madenwald, Tamra, Socquet, Muriel, Barac, Aleksandra, Ilieva-Borisova, Yordanka, Pelemiš, Mijomir, Flores, Jorge, "Safety and immunogenicity of a seasonal trivalent inactivated split influenza vaccine: a phase I randomized clinical trial in healthy Serbian adults" in Human Vaccines & Immunotherapeutics, 14, no. 3 (2018):579-586,
https://doi.org/10.1080/21645515.2017.1415683 .,
conv_427 .
15
4
2
4