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Catecholaminergic signalling through thymic nerve fibres, thymocytes and stromal cells is dependent on both circulating and locally synthesized glucocorticoids
(Wiley-Blackwell, Hoboken, 2012)
Glucocorticoids have been shown to modulate the expression of noradrenaline metabolizing enzymes and beta(2)- and alpha(1B)-adrenoceptors in a tissue- and cell- specific manner. In the thymus, apart from extensive sympathetic ...
Glucocorticoids, master modulators of the thymic catecholaminergic system?
(Assoc Bras Divulg Cientifica, Ribeirao Preto, 2010)
There is evidence that the major mediators of stress, i.e., catecholamines and glucocorticoids, play an important role in modulating thymopoiesis and consequently immune responses. Furthermore, there are data suggesting ...
Aging impairs endocytic capacity of splenic dendritic cells from dark agouti rats and alters their response to TLR4 stimulation
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2015)
The study was undertaken considering: i) that relative proportion of distinct subsets of splenic dendritic cells (DCs) is strain-specific and predictive for the susceptibility to autoimmune diseases; ii) age-related changes ...
Aging affects rat inflammatory peritoneal exudate composition and macrophage inflammatory mediator production in a strain-dependent manner
(Immunological society of SerbiaUniversity of Kragujevac, Faculty of medical sciences, 2015)
The present study was designed to examine influence of aging on
macrophage proinflammatory/anti-inflammatory capacity in rat model of
thioglycollate-induced peritonitis. Peritoneal macrophages were isolated
from young ...
The Ocular Conjunctiva as a Mucosal Immunization Route: A Profile of the Immune Response to the Model Antigen Tetanus Toxoid
(Public Library Science, San Francisco, 2013)
Background: In a quest for a needle-free vaccine administration strategy, we evaluated the ocular conjunctiva as an alternative mucosal immunization route by profiling and comparing the local and systemic immune responses ...
Effectiveness of Wharton's jelly stem cells in gastroschisis repair using the inner surface of the umbilical cord as a patch: long-term results
(Lippincott Williams & Wilkins, Philadelphia, 2015)
Objective This retrospective study was designed to assess and compare the anatomical, functional, and esthetic appearance of the umbilical area in patients after repair of gastroschisis using the inner surface of the ...
Profiling of microorganism-binding serum antibody specificities in professional athletes
(Public Library Science, San Francisco, 2018)
The goal of this work was to elucidate similarities between microorganisms from the perspective of the humoral immune system reactivity in professional athletes. The reactivity of serum IgG of 14 young, individuals was ...
Deep and quantitative profiling of PTMs in ecologically preserved and polluted pollen proteomes of timothy grass reveals predominant source of contamination
(Srpsko Udruženje za Proteomiku, SePA; IBISS, 2018)
Objective: to create method for unrestrictive deep, relative quantification of post translationalmodifications (PTMs) within different proteomes. Pollution field studies of bio indicators such aspollen are valuable because ...
Peritoneal exudate cells from long-lived rats exhibit increased IL-10/IL-1 beta expression ratio and preserved NO/urea ratio following LPS-stimulation in vitro
(Springer, Dordrecht, 2014)
In humans, usual aging, differently from successful aging, is associated with deregulation of proinflammatory/anti-inflammatory cytokine balance. The corresponding data from rat studies are limited. Therefore, we examined ...
The effect of infectious dose on humoral and cellular immune responses in Chlamydophila caviae primary ocular infection
(Public Library Science, San Francisco, 2017)
Following infection, the balance between protective immunity and immunopathology often depends on the initial infectious load. Several studies have investigated the effect of infectious dose; however, the mechanism by which ...