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The effects of chronic stress on thymus innervation in the adult rat
(Elsevier Gmbh, Munich, 2005)
Various stressors induce changes in the immune system. However, it has not yet been analyzed how stressors affect thymus innervation. To examine whether chronic stress alters the morphology of the thymus by changing the ...
In vivo modulation of the splenocyte yield and composition by female sex steroid hormones
(Govi-Verlag Gmbh, Eschborn, 2001)
The study was designed to shed more light on the controversial role of the two main ovarian steroid hormones (i.e. estradiol and progesterone) in shaping the size and phenotypic characteristics of the splenic lymphocyte ...
Androgens Contribute to Age-Associated Changes in Peripheral T-Cell Homeostasis Acting in a Thymus-Independent Way
(Karger, Basel, 2014)
Objective: Considering a causal role of androgens in thymic involution, age-related remodeling of peripheral T-cell compartments in the absence of testicular hormones was evaluated. Methods: Rats were orchidectomized (ORX) ...
Hexameric immunoglobulin M in humans: Desired or unwanted?
(Churchill Livingstone, Edinburgh, 2011)
Immunoglobulin M (IgM) is the first antibody produced upon infection, and is often suggested as the first line of defense of human immune system. In addition to being present on the surface of naive B cells as a monomeric ...
Neonatal androgenization affects the intrathymic T-cell maturation in rats
(Karger, Basel, 2005)
The thymus structure, expression of CD4/CD8/TCR alpha beta on thymocytes and thymocyte proliferative and apoptotic indexes were analyzed in sexually immature 30-day-old and in sexually mature 60-day-old female rats neonatally ...
Strain differences and the role for HSP47 and HSP70 in adjuvant arthritis in rats
(Wiley, Hoboken, 2006)
Because of high sequence homology between microbial and endogenous heat shock proteins (HSP), immunological cross-reactivity to microbial HSP has been suggested as a possible cause of the development of autoimmune diseases, ...
Age-associated reshaping of the thymocyte differentiation model in male rats / Promene u modelu diferentovanja timocita u mužjaka pacova sa godinama
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2001)
In order to elucidate the features of putative age-related changes in the intrathymic T cell maturation sequence, the thymus weight, thymocyte yield and relative proportions of thymocyte subsets were analyzed at distinct ...
Selected Microorganisms from an Antibody Binding Perspective in Professional Athletes
(Lippincott Williams & Wilkins, Philadelphia, 2018)
Effects of catecholamines on thymocyte apoptosis and proliferation depend on thymocyte microenvironment
(Elsevier, Amsterdam, 2014)
The present study, through quantification of tyrosine hydroxylase (TH) expression and catecholamine (CA) content in the presence and in the absence of alpha-methyl-p-tyrosine (AMPT), a TH inhibitor, in adult thymic organ ...
Strain differences in the humoral immune response to commensal bacterial antigens in rats
(Akademiai Kiado Rt, Budapest, 2013)
We have investigated the immune response to commensal bacterial species in the two inbred rat strains: Dark Agouti (DA) and Albino Oxford (AO). The predominant Gram-negative aerobe in our rats' intestinal bacterial flora ...