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Neuroprotective effect of chronic verapamil treatment on cognitive and noncognitive deficits in an experimental Alzheimer's disease in rats
(Taylor & Francis Ltd, Abingdon, 1997)
It is well known that disturbance of calcium homeostasis has a significant role in the development of neurodegenerative disorders, such as Alzheimer's disease (AD). Our recent data suggest that acute treatment with the ...
Effect of physostigmine and verapamil on active avoidance in an experimental model of Alzheimer's disease
(Taylor & Francis Ltd, Abingdon, 1997)
The present study was performed to investigate and compare the effect of acetylcholinesterase inhibitor, physostigmine (0.045, 0.060 and 0.075 mg/kg sc, 30 min before the tests) and Ca-antagonist, verapamil (1.0, 2.5, 5.0 ...
Open field behavior in nucleus basalis magnocellularis-lesioned rats treated with physostigmine and verapamil
(Taylor & Francis Ltd, Abingdon, 1997)
The present study was done to investigate and compare the effect of acetylcholinesterase inhibitor, physostigmine (0.030, 0.045, 0.060 and 0.075 mg/kg sc) and Ca-antagonist, verapamil (1.0, 2.5, 5.0 and 10.0 mg/kg sc) on ...
The neuronal and immune memory systems as supervisors of neural plasticity and aging of the brain - From phenomenology to coding of information
(New York Acad Sciences, New York, 2005)
The ultimate goal of this report is to learn how to manipulate the level of memory T cells for more effective treatment of such neurological diseases as multiple sclerosis (MS), where certain T cell subsets recognize ...
Importance of immunological and inflammatory processes in the pathogenesis and therapy of Alzheimer's disease
(Taylor & Francis Ltd, Abingdon, 1998)
The contribution of autoimmune processes or inflammatory components in the etiology and pathogenesis of Alzheimer's disease (AD) has been suspected for many years. The presence of antigen-presenting, HLA-DR-positive and ...
Behavioral and adaptive status in an experimental model of Alzheimer's disease in rats
(Taylor & Francis Ltd, Abingdon, 1996)
Ten days after bilateral electrolytic lesions of nucleus basalis magnocellularis (NBM) we tested behavioral (spontaneous motor activity, acquisition and performance of two-way active avoidance, fear-response in open field ...
Learning and memory in nucleus basalis magnocellularis-lesioned rats after transplantation of fetal frontal cortex
(Taylor & Francis Ltd, Abingdon, 1997)
The effect of fetal frontal cortex transplantation on behaviour performance was examined in adult male Wistar rats with lesions of the nucleus basalis magnocellularis (NBM). Compared to intact and sham-operated controls, ...
Aging, aluminium and basal forebrain lesions modify substrate kinetics of erythrocyte membrane Na, K-ATPase in the rat
(IOS Press, Amsterdam, 2008)
Several studies suggested that the activity of erythrocyte Na, K-ATPase declines with aging. Here, it is postulated that alterations in the substrate kinetics of the erythrocyte membrane Na, K-ATPase could be more aggravated ...
Effect of acute physostigmine and verapamil treatment on aggressive and depressive behavior in rats with lesioned nucleus basalis magnocellularis
(Wiley, Hoboken, 1998)
In order to investigate the effects of physostigmine and verapamil on aggressive (test of foot shock induced aggression) and depressive (learned helplessness test) behavior, ten days after bilateral lesions of the nucleus ...
Effect of acute verapamil treatment on body temperature in nucleus basalis magnocellularis-lesioned rats
(Wiley, Hoboken, 1998)
Our recent studies suggest that lesions of the nucleus basalis magnocellularis (nbm) in rats induce a significant decrease of core body temperature in standard laboratory conditions. Considering the importance of calcium ...