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Приказ резултата 231-240 од 262
Antigenic specificity and expression of a natural idiotope on human pentameric and hexameric IgM polymers
(Humana Press Inc, Totowa, 2011)
Natural antibodies (NAbs) are present in circulation even before the exposure to antigen and they exert various biological functions. They are polyreactive and mainly represented by immunoglobulin M (IgM), which is the ...
Infectious dose and repeated infections are key factors influencing immune response characteristics in guinea pig ocular chlamydial infection
(Elsevier Science Bv, Amsterdam, 2016)
The aim of this study was to determine whether infectious dose of Chlamydia caviae after repeated infections influences the immunological responses and subsequent clearance of pathogen at the ocular surface of guinea pigs. ...
Prophylactic effect of recombinant banana lectin on TNBS-induced colitis in BALB/c mice
(Wiley, Hoboken, 2017)
Oral treatment with Lactobacillus rhamnosus 64 during the early postnatal period improves the health of adult rats with TNBS-induced colitis
(Elsevier Science Bv, Amsterdam, 2018)
The current study investigated a potential modulating effect of orally applied Lactobacillus rhamnosus 64 (LB64) during the early postnatal period (day of life: similar to 3-30), during young adult period (day of life: ...
The involvement of estrogen receptors alpha and beta in the in vitro effects of 17 beta-estradiol on secretory profile of peritoneal macrophages from naturally menopausal female and middle-aged male rats
(Pergamon-Elsevier Science Ltd, Oxford, 2018)
The systemic and extra- gonadal levels of 17 beta-estradiol (E2) change during aging, and affect the expression of estrogen receptors (ERs) in the immune cells of both females and males. The age-related cessation of ovarian ...
Rat strain differences in peritoneal immune cell response to selected gut microbiota: A crossroad between tolerance and autoimmunity?
(Pergamon-Elsevier Science Ltd, Oxford, 2018)
Aims: Some gut commensals can be protective, whereas others are implicated as necessary for development of inflammatory/autoimmune diseases. Peritoneal immune cells may play an important role in promoting auto-immunity in ...
Sex Differences in Macrophage Functions in Middle-Aged Rats: Relevance of Estradiol Level and Macrophage Estrogen Receptor Expression
(Springer/Plenum Publishers, New York, 2017)
The aim of this study was to examine the influence of sex on age-related changes in phenotype and functional capacity of rat macrophages. The potential role of estradiol as a contributing factor to a sex difference in ...
Strain-dependent response to stimulation in middle-aged rat macrophages: A quest after a useful indicator of healthy aging
(Pergamon-Elsevier Science Ltd, Oxford, 2016)
Rats of Albino Oxford (AO) strain in our animal facility exhibit a longer average healthy life span than rats of Dark Agouit (DA) strain. Since chronic activation of macrophages contributes to chronic low level inflammation ...
Unopposed Estrogen Supplementation/Progesterone Deficiency in Post-Reproductive Age Affects the Secretory Profile of Resident Macrophages in a Tissue-Specific Manner in the Rat
(Wiley, Hoboken, 2015)
Problem The influence of unopposed estrogen replacement/isolated progesterone deficiency on macrophage production of pro-inflammatory/anti-inflammatory mediators in the post-reproductive age was studied. Method of study ...
Aging affects the responsiveness of rat peritoneal macrophages to GM-CSF and IL-4
(Springer, New York, 2016)
Macrophages undergo significant functional alterations during aging. The aim of the present study was to investigate changes of rat macrophage functions and response to M1/M2 polarization signals with age. Therefore, ...