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Exploring E. coli-based expression of genetically inactivated tetanus toxin for vaccine development
(Serbian Society for Microbiology, 2024)
Tetanus toxin, a highly potent neurotoxin produced by Clostridium tetani, is the primary agent responsible for causing tetanus. This serious, potentially fatal disease can be effectively prevented through vaccination. ...
Inactivation of diphtheria toxin by site-directed mutagenesis
(Serbian Society for Microbiology, 2024)
Diphtheria toxin is a single polypeptide chain produced by toxigenic strains of Corynebacterium diphtheriae that causes the disease diphtheria in humans by gaining entry into the cytoplasm of cells and inhibiting protein ...
Diphtheria and tetanus vaccines: a historical overview, present achievements, and future directions
(Serbian Society for Microbiology, 2024)
Diphtheria and tetanus, once formidable causes of morbidity and mortality worldwide, have seen their threats markedly diminished through the advent and widespread use of vaccines. This review article delves into the ...