Resurgence of measles in Serbia 2010-2011 highlights the need for supplementary immunization activities
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2016
Authors
Nedeljković, JasminkaRakić-Adrović, Slavica
Tasić, G.
Kovačević-Jovanović, Vesna
Lončarević, Goranka
Huebschen, Judith M.
Muller, Claude P.
Article (Published version)
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Between December 2010 and August 2011 an outbreak of measles occurred in Serbia with 363 reported cases. Sera and/or nose/throat swabs were collected from 193 patients and tested for measles-specific IgM antibodies by ELISA and viral RNA by RT-PCR, respectively. Epidemiological data were obtained from the surveillance database of the Institute of Public Health of Serbia. Of the 363 cases involved in the outbreak, 113 were laboratory confirmed. More than one third of the patients were hospitalized (n = 130, 35.8%) and for 15 (4.1% of the reported outbreak cases) the infection was complicated by pneumonia. Mostly pre-school children aged lt = 4 years (37.8%) and adults aged gt = 30 years (27.3%) were affected. The majority of patients belonged to the Roma population with a preponderance of female cases (57.0%). Nearly 94% of the patients were either unvaccinated or of unknown vaccination status. The main outbreak virus was the D4-Hamburg strain. The outbreak in Serbia occurred after se...veral years of very low measles incidence despite a high routine immunization coverage in the general population, suggesting that special efforts to identify and vaccinate susceptible population groups are required even in countries with apparently good disease control.
Keywords:
Measles virus / molecular epidemiology / outbreakSource:
Epidemiology and Infection, 2016, 144, 5, 1121-1128Publisher:
- Cambridge Univ Press, New York
Funding / projects:
- Serbian Ministry of Health
- Luxembourg Ministry of Foreign Affairs
DOI: 10.1017/S0950268815002277
ISSN: 0950-2688
PubMed: 26449667
WoS: 000371720700025
Scopus: 2-s2.0-84943328223
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TorlakTY - JOUR AU - Nedeljković, Jasminka AU - Rakić-Adrović, Slavica AU - Tasić, G. AU - Kovačević-Jovanović, Vesna AU - Lončarević, Goranka AU - Huebschen, Judith M. AU - Muller, Claude P. PY - 2016 UR - http://intor.torlakinstitut.com/handle/123456789/468 AB - Between December 2010 and August 2011 an outbreak of measles occurred in Serbia with 363 reported cases. Sera and/or nose/throat swabs were collected from 193 patients and tested for measles-specific IgM antibodies by ELISA and viral RNA by RT-PCR, respectively. Epidemiological data were obtained from the surveillance database of the Institute of Public Health of Serbia. Of the 363 cases involved in the outbreak, 113 were laboratory confirmed. More than one third of the patients were hospitalized (n = 130, 35.8%) and for 15 (4.1% of the reported outbreak cases) the infection was complicated by pneumonia. Mostly pre-school children aged lt = 4 years (37.8%) and adults aged gt = 30 years (27.3%) were affected. The majority of patients belonged to the Roma population with a preponderance of female cases (57.0%). Nearly 94% of the patients were either unvaccinated or of unknown vaccination status. The main outbreak virus was the D4-Hamburg strain. The outbreak in Serbia occurred after several years of very low measles incidence despite a high routine immunization coverage in the general population, suggesting that special efforts to identify and vaccinate susceptible population groups are required even in countries with apparently good disease control. PB - Cambridge Univ Press, New York T2 - Epidemiology and Infection T1 - Resurgence of measles in Serbia 2010-2011 highlights the need for supplementary immunization activities EP - 1128 IS - 5 SP - 1121 VL - 144 DO - 10.1017/S0950268815002277 ER -
@article{ author = "Nedeljković, Jasminka and Rakić-Adrović, Slavica and Tasić, G. and Kovačević-Jovanović, Vesna and Lončarević, Goranka and Huebschen, Judith M. and Muller, Claude P.", year = "2016", abstract = "Between December 2010 and August 2011 an outbreak of measles occurred in Serbia with 363 reported cases. Sera and/or nose/throat swabs were collected from 193 patients and tested for measles-specific IgM antibodies by ELISA and viral RNA by RT-PCR, respectively. Epidemiological data were obtained from the surveillance database of the Institute of Public Health of Serbia. Of the 363 cases involved in the outbreak, 113 were laboratory confirmed. More than one third of the patients were hospitalized (n = 130, 35.8%) and for 15 (4.1% of the reported outbreak cases) the infection was complicated by pneumonia. Mostly pre-school children aged lt = 4 years (37.8%) and adults aged gt = 30 years (27.3%) were affected. The majority of patients belonged to the Roma population with a preponderance of female cases (57.0%). Nearly 94% of the patients were either unvaccinated or of unknown vaccination status. The main outbreak virus was the D4-Hamburg strain. The outbreak in Serbia occurred after several years of very low measles incidence despite a high routine immunization coverage in the general population, suggesting that special efforts to identify and vaccinate susceptible population groups are required even in countries with apparently good disease control.", publisher = "Cambridge Univ Press, New York", journal = "Epidemiology and Infection", title = "Resurgence of measles in Serbia 2010-2011 highlights the need for supplementary immunization activities", pages = "1128-1121", number = "5", volume = "144", doi = "10.1017/S0950268815002277" }
Nedeljković, J., Rakić-Adrović, S., Tasić, G., Kovačević-Jovanović, V., Lončarević, G., Huebschen, J. M.,& Muller, C. P.. (2016). Resurgence of measles in Serbia 2010-2011 highlights the need for supplementary immunization activities. in Epidemiology and Infection Cambridge Univ Press, New York., 144(5), 1121-1128. https://doi.org/10.1017/S0950268815002277
Nedeljković J, Rakić-Adrović S, Tasić G, Kovačević-Jovanović V, Lončarević G, Huebschen JM, Muller CP. Resurgence of measles in Serbia 2010-2011 highlights the need for supplementary immunization activities. in Epidemiology and Infection. 2016;144(5):1121-1128. doi:10.1017/S0950268815002277 .
Nedeljković, Jasminka, Rakić-Adrović, Slavica, Tasić, G., Kovačević-Jovanović, Vesna, Lončarević, Goranka, Huebschen, Judith M., Muller, Claude P., "Resurgence of measles in Serbia 2010-2011 highlights the need for supplementary immunization activities" in Epidemiology and Infection, 144, no. 5 (2016):1121-1128, https://doi.org/10.1017/S0950268815002277 . .