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dc.creatorDimitrijević, Rajna
dc.creatorStojanović, Marijana
dc.creatorMicić, M.
dc.creatorDimitrijević, Ljiljana
dc.creatorGavrović-Jankulović, Marija
dc.date.accessioned2021-02-18T10:39:00Z
dc.date.available2021-02-18T10:39:00Z
dc.date.issued2012
dc.identifier.issn1756-4646
dc.identifier.urihttp://intor.torlakinstitut.com/handle/123456789/354
dc.description.abstractTo explore the potential usage of recombinant banana lectin as an immunostimulator it was of interest to analyze the effect it exerted in vivo in mice, upon two different routes of exposure. By Western blotting analysis of the gastric and intestinal luminal content it was found that recombinant banana lectin is stable in vivo in the mouse digestive tract, where it specifically interacts with the mucosal surfaces which can be inhibited by the addition of glucose. Its attachment to mice jejunum has been confirmed by immunofluorescence. In addition, it was able to induce systemic immunity, evidenced by specific antibody production, by oral application, a property that might be exploited for the induction of systemic immune responses. (c) 2012 Elsevier Ltd. All rights reserved.en
dc.publisherElsevier, Amsterdam
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172049/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/175053/RS//
dc.rightsrestrictedAccess
dc.sourceJournal of Functional Foods
dc.subjectRecombinant banana lectinen
dc.subjectMouse digestive tracten
dc.subjectAntibody subclass profileen
dc.titleRecombinant banana lectin as mucosal immunostimulatoren
dc.typearticle
dc.rights.licenseARR
dc.citation.epage641
dc.citation.issue3
dc.citation.other4(3): 636-641
dc.citation.rankM21
dc.citation.spage636
dc.citation.volume4
dc.identifier.doi10.1016/j.jff.2012.04.003
dc.identifier.rcubconv_295
dc.identifier.scopus2-s2.0-84861671490
dc.identifier.wos000305492100008
dc.type.versionpublishedVersion


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