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The activity of ofloxacin against methicillin-resistant staphylococcus aureus
dc.creator | Mraović, Mirjana | |
dc.creator | Čanić-Radojlović, M. | |
dc.date.accessioned | 2021-02-18T10:16:43Z | |
dc.date.available | 2021-02-18T10:16:43Z | |
dc.date.issued | 1986 | |
dc.identifier.issn | 0300-8126 | |
dc.identifier.uri | http://intor.torlakinstitut.com/handle/123456789/30 | |
dc.description.abstract | The return of multiresistant Staphylococcus aureus strains and the appearance of methicillin-resistant strains resistant as well to rifampin and fusidic acid increase the need for new agents to treat infections caused by such strains. Ofloxacin susceptibility of 109 selected methicillin-resistant staphylococci (with MIC90 of 1,000 mg/l for methicillin, 1.3% being resistant to gentamicin with MICs ranging from 25 to 100 mg/l, chloramphenicol MICs ranging from 25 to 100 mg/l and resistant to β-lactam-antibiotics and clindamycin), was determined by an agar dilution method. MICs of ofloxacin for methicillin-resistant staphylococci ranged from 0.09 to 0.78 mg/l, with an MIC90 of 0.39 mg/l. The in vitro results suggest a possible clinical role for ofloxacin in infections caused by methicillin-resistant staphylococci. However, further investigations are needed. | en |
dc.publisher | Springer-Verlag | |
dc.rights | restrictedAccess | |
dc.source | Infection | |
dc.title | The activity of ofloxacin against methicillin-resistant staphylococcus aureus | en |
dc.type | article | |
dc.rights.license | ARR | |
dc.citation.epage | S232 | |
dc.citation.issue | 4 Supplement | |
dc.citation.other | 14(4 Supplement): S231-S232 | |
dc.citation.rank | M22 | |
dc.citation.spage | S231 | |
dc.citation.volume | 14 | |
dc.identifier.doi | 10.1007/BF01661278 | |
dc.identifier.pmid | 3469151 | |
dc.identifier.scopus | 2-s2.0-0022845799 | |
dc.type.version | publishedVersion |