The return of multiresistant Staphylococcus aureus strains and the appearance of methicillin-resistant strains resistant as well to rifampin and fusidic acid increase the need for new agents to treat infections caused by such strains. Ofloxacin susceptibility of 109 selected methicillin-resistant staphylococci (with MIC90 of 1,000 mg/l for methicillin, 1.3% being resistant to gentamicin with MICs ranging from 25 to 100 mg/l, chloramphenicol MICs ranging from 25 to 100 mg/l and resistant to β-lactam-antibiotics and clindamycin), was determined by an agar dilution method. MICs of ofloxacin for methicillin-resistant staphylococci ranged from 0.09 to 0.78 mg/l, with an MIC90 of 0.39 mg/l. The in vitro results suggest a possible clinical role for ofloxacin in infections caused by methicillin-resistant staphylococci. However, further investigations are needed.
TY - JOUR
AU - Mraović, Mirjana
AU - Čanić-Radojlović, M.
PY - 1986
UR - http://intor.torlakinstitut.com/handle/123456789/30
AB - The return of multiresistant Staphylococcus aureus strains and the appearance of methicillin-resistant strains resistant as well to rifampin and fusidic acid increase the need for new agents to treat infections caused by such strains. Ofloxacin susceptibility of 109 selected methicillin-resistant staphylococci (with MIC90 of 1,000 mg/l for methicillin, 1.3% being resistant to gentamicin with MICs ranging from 25 to 100 mg/l, chloramphenicol MICs ranging from 25 to 100 mg/l and resistant to β-lactam-antibiotics and clindamycin), was determined by an agar dilution method. MICs of ofloxacin for methicillin-resistant staphylococci ranged from 0.09 to 0.78 mg/l, with an MIC90 of 0.39 mg/l. The in vitro results suggest a possible clinical role for ofloxacin in infections caused by methicillin-resistant staphylococci. However, further investigations are needed.
PB - Springer-Verlag
T2 - Infection
T1 - The activity of ofloxacin against methicillin-resistant staphylococcus aureus
EP - S232
IS - 4 Supplement
SP - S231
VL - 14
DO - 10.1007/BF01661278
UR - conv_559
ER -
@article{
author = "Mraović, Mirjana and Čanić-Radojlović, M.",
year = "1986",
abstract = "The return of multiresistant Staphylococcus aureus strains and the appearance of methicillin-resistant strains resistant as well to rifampin and fusidic acid increase the need for new agents to treat infections caused by such strains. Ofloxacin susceptibility of 109 selected methicillin-resistant staphylococci (with MIC90 of 1,000 mg/l for methicillin, 1.3% being resistant to gentamicin with MICs ranging from 25 to 100 mg/l, chloramphenicol MICs ranging from 25 to 100 mg/l and resistant to β-lactam-antibiotics and clindamycin), was determined by an agar dilution method. MICs of ofloxacin for methicillin-resistant staphylococci ranged from 0.09 to 0.78 mg/l, with an MIC90 of 0.39 mg/l. The in vitro results suggest a possible clinical role for ofloxacin in infections caused by methicillin-resistant staphylococci. However, further investigations are needed.",
publisher = "Springer-Verlag",
journal = "Infection",
title = "The activity of ofloxacin against methicillin-resistant staphylococcus aureus",
pages = "S232-S231",
number = "4 Supplement",
volume = "14",
doi = "10.1007/BF01661278",
url = "conv_559"
}
Mraović, M.,& Čanić-Radojlović, M.. (1986). The activity of ofloxacin against methicillin-resistant staphylococcus aureus. in Infection
Springer-Verlag., 14(4 Supplement), S231-S232.
https://doi.org/10.1007/BF01661278
conv_559
Mraović M, Čanić-Radojlović M. The activity of ofloxacin against methicillin-resistant staphylococcus aureus. in Infection. 1986;14(4 Supplement):S231-S232.
doi:10.1007/BF01661278
conv_559 .
Mraović, Mirjana, Čanić-Radojlović, M., "The activity of ofloxacin against methicillin-resistant staphylococcus aureus" in Infection, 14, no. 4 Supplement (1986):S231-S232,
https://doi.org/10.1007/BF01661278 .,
conv_559 .
