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Age-Associated Remodeling of Thymopoiesis: Role for Gonadal Hormones and Catecholamines
(Karger, Basel, 2008)
The present review summarizes recent data on age-related thymic changes termed thymic involution, and highlights the putative role of perturbances in extrathymical and, possibly, intrathymical production of gonadal steroids ...
Catecholamines as immunomodulators: A role for adrenoceptor-mediated mechanisms in fine tuning of T-cell development
(Elsevier Science Bv, Amsterdam, 2008)
In its simplest form, effective T cell-mediated immunity emanates from the expansion of specific T cells activated tit response to antigen. In establishing and maintaining the peripheral T-cell pool, the thymus plays a ...