HD phenocopies - Possible role of saitohin gene
Samo za registrovane korisnike
2008
Autori
Janković, N.Kemanović, M.
Dimitrijević, Rajna
Keckarević-Marković, Milica
Dobričić, Valerija
Savić-Pavićević, Dušanka
Romac, Stanka
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Saitohin (STH) is located in the intron of the human gene for microtubule-associated protein tau. Q7R polymorphism has been identified in the STH gene. Some neurodegenerative disorders were found to be associated with the presence of certain STH allele. This study genotyped 37 subjects with diagnosis of Huntington's disease, but lacking mutations in HD, PRNP, JPH-3, and FTL genes for STH polymorphism. It was determined that Q allele of STH gene was over-represented in a tested group of patients (P gt Pt). Over-representation of Q allele in a group of patients might be considered as genetic risk factor for HD like diseases.
Ključne reči:
HD phenocopies / microtubule-associated protein tau / neurodegenerative diseases / peroxiredoxin 6 / polymorphism / SaitohinIzvor:
International Journal of Neuroscience, 2008, 118, 3, 391-397Izdavač:
- Taylor & Francis Ltd, Abingdon
Finansiranje / projekti:
- Molekularna genetika naslednih neurodegenerativnih i psihijatrijskih oboljenja (RS-MESTD-MPN2006-2010-143013)
DOI: 10.1080/00207450701593103
ISSN: 0020-7454
PubMed: 18300012
WoS: 000253720600008
Scopus: 2-s2.0-40049098967
Institucija/grupa
TorlakTY - JOUR AU - Janković, N. AU - Kemanović, M. AU - Dimitrijević, Rajna AU - Keckarević-Marković, Milica AU - Dobričić, Valerija AU - Savić-Pavićević, Dušanka AU - Romac, Stanka PY - 2008 UR - http://intor.torlakinstitut.com/handle/123456789/251 AB - Saitohin (STH) is located in the intron of the human gene for microtubule-associated protein tau. Q7R polymorphism has been identified in the STH gene. Some neurodegenerative disorders were found to be associated with the presence of certain STH allele. This study genotyped 37 subjects with diagnosis of Huntington's disease, but lacking mutations in HD, PRNP, JPH-3, and FTL genes for STH polymorphism. It was determined that Q allele of STH gene was over-represented in a tested group of patients (P gt Pt). Over-representation of Q allele in a group of patients might be considered as genetic risk factor for HD like diseases. PB - Taylor & Francis Ltd, Abingdon T2 - International Journal of Neuroscience T1 - HD phenocopies - Possible role of saitohin gene EP - 397 IS - 3 SP - 391 VL - 118 DO - 10.1080/00207450701593103 ER -
@article{ author = "Janković, N. and Kemanović, M. and Dimitrijević, Rajna and Keckarević-Marković, Milica and Dobričić, Valerija and Savić-Pavićević, Dušanka and Romac, Stanka", year = "2008", abstract = "Saitohin (STH) is located in the intron of the human gene for microtubule-associated protein tau. Q7R polymorphism has been identified in the STH gene. Some neurodegenerative disorders were found to be associated with the presence of certain STH allele. This study genotyped 37 subjects with diagnosis of Huntington's disease, but lacking mutations in HD, PRNP, JPH-3, and FTL genes for STH polymorphism. It was determined that Q allele of STH gene was over-represented in a tested group of patients (P gt Pt). Over-representation of Q allele in a group of patients might be considered as genetic risk factor for HD like diseases.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "International Journal of Neuroscience", title = "HD phenocopies - Possible role of saitohin gene", pages = "397-391", number = "3", volume = "118", doi = "10.1080/00207450701593103" }
Janković, N., Kemanović, M., Dimitrijević, R., Keckarević-Marković, M., Dobričić, V., Savić-Pavićević, D.,& Romac, S.. (2008). HD phenocopies - Possible role of saitohin gene. in International Journal of Neuroscience Taylor & Francis Ltd, Abingdon., 118(3), 391-397. https://doi.org/10.1080/00207450701593103
Janković N, Kemanović M, Dimitrijević R, Keckarević-Marković M, Dobričić V, Savić-Pavićević D, Romac S. HD phenocopies - Possible role of saitohin gene. in International Journal of Neuroscience. 2008;118(3):391-397. doi:10.1080/00207450701593103 .
Janković, N., Kemanović, M., Dimitrijević, Rajna, Keckarević-Marković, Milica, Dobričić, Valerija, Savić-Pavićević, Dušanka, Romac, Stanka, "HD phenocopies - Possible role of saitohin gene" in International Journal of Neuroscience, 118, no. 3 (2008):391-397, https://doi.org/10.1080/00207450701593103 . .