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dc.creatorDimitrijević, Mirjana
dc.creatorStanojević, Stanislava
dc.creatorMicić, Stana
dc.creatorVujić, Vesna
dc.creatorKovačević-Jovanović, Vesna
dc.creatorMitić, Katarina
dc.creatorvon Hoersten, Stephan
dc.creatorKosec, Duško
dc.date.accessioned2021-02-18T10:29:38Z
dc.date.available2021-02-18T10:29:38Z
dc.date.issued2006
dc.identifier.issn0196-9781
dc.identifier.urihttp://intor.torlakinstitut.com/handle/123456789/218
dc.description.abstractWe studied the effects of neuropeptide Y (NPY) and NPY-related receptor specific peptides on functions of carrageenan-elicited granulocytes in vitro and ability of NPY to modulate carrageenan-induced air pouch inflammation in rats in vivo. Anti-inflammatory effect of NPY comprises reduced granulocyte accumulation into the air pouch, to some extent attenuation of phagocytosis, attained via Y1 receptor, and considerable decrease in peroxide production, albeit mediated via Y2 and Y5 receptors activation. Conversely, NPY increases nitric oxide production and this potentiation is mediated via Y1 receptor. It is concluded that NPY Y1 and Y2/Y5 receptors' interaction participates in NPY-induced modulation of granulocyte functions related to inflammation. (c) 2006 Elsevier Inc. All rights reserved.en
dc.publisherElsevier Science Inc, New York
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/145049/RS//
dc.rightsrestrictedAccess
dc.sourcePeptides
dc.subjectneuropeptide y (NPY)en
dc.subjectNPY receptorsen
dc.subjectinflammationen
dc.subjectgranulocytes raten
dc.titleNeuropeptide Y (NPY) modulates oxidative burst and nitric oxide production in carrageenan-elicited granulocytes from rat air pouchen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage3215
dc.citation.issue12
dc.citation.other27(12): 3208-3215
dc.citation.rankM22
dc.citation.spage3208
dc.citation.volume27
dc.identifier.doi10.1016/j.peptides.2006.08.018
dc.identifier.pmid17010476
dc.identifier.rcubconv_109
dc.identifier.scopus2-s2.0-33750959354
dc.identifier.wos000242821300022
dc.type.versionpublishedVersion


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