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dc.creatorPapa, Anna
dc.creatorPapadimitriou, E.
dc.creatorBožović, Bojana
dc.creatorAntoniadis, Antonis
dc.date.accessioned2021-02-18T10:28:21Z
dc.date.available2021-02-18T10:28:21Z
dc.date.issued2005
dc.identifier.issn0146-6615
dc.identifier.urihttp://intor.torlakinstitut.com/handle/123456789/199
dc.description.abstractCrimean-Congo hemorrhagic fever (CCHF) virus causes one of the most severe diseases in humans, with a mortality rate of up to 30%. It is transmitted to humans by the bite of hard ticks or by contact with blood or tissues from human patients or infected livestock. Balkan Peninsula is an endemic region of the disease, and sporadic cases or even outbreaks are observed every year. The M RNA segment encodes for the glycoprotein precursor of two surface glycoproteins Gn and Gc. Up to now complete M RNA CCHF virus sequences have been published from strains isolated in Nigeria, China, Pakistan, Tajikistan, and Russia. In the present study, the genetic characterization of the complete nucleotide sequence of the M RNA segment of a Balkan CCHF virus strain, Kosovo/9553/2001, isolated in summer of 2001 from a human fatal case in Kosovo is reported. This is the first published complete M nucleotide sequence of a CCHF virus strain isolated in Balkans. It was found that the Balkan strain is similar to the Russian strain, both strains differing from all other completely sequenced CCHF virus strains by approximately 22% at the nucleotide level forming an independent clade in the phylogenetic tree. (C) 2005 Wiley-Liss, Inc.en
dc.publisherWiley, Hoboken
dc.rightsrestrictedAccess
dc.sourceJournal of Medical Virology
dc.subjectCrimean-Congo hemorrhagic feveren
dc.subjectM segmenten
dc.subjectgenetic characterizationen
dc.subjectglycoproteinen
dc.subjectKosovoen
dc.titleGenetic characterization of the M RNA segment of a Balkan Crimean-Congo hemorrhagic fever virus strainen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage469
dc.citation.issue3
dc.citation.other75(3): 466-469
dc.citation.rankM23
dc.citation.spage466
dc.citation.volume75
dc.identifier.doi10.1002/jmv.20290
dc.identifier.pmid15648072
dc.identifier.rcubconv_167
dc.identifier.scopus2-s2.0-12944305740
dc.identifier.wos000226700900016
dc.type.versionpublishedVersion


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