Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases
Нема приказа
Аутори
Bogić, MirjanaRašković, S.
Sojić, J.
Boricić, I.
Ješić, R.
Burazer, Lidija
Spirić, V.T.
Popadić, A.P.
Đurić, V.
Celeketić, D.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Drug hypersensitivity syndrome is a severe form of hypersensitivity to the antiepileptic agent carbamazepine, particularly in presence of visceral and hematological manifestations that must be evidenced and treated in time. Two cases of female patients with carbamazepine-induced hypersensitivity syndrome are reported. Both patients had prominent general complaints (febricity, weakness). The first patient had leukopenia, lymphadenopathy and rash, while the other one had urticaria, angioedema and hepatitis after administration of carbamazepine. Hypersensitivity reactions induced by antiepileptics widely applied in the practice may be severe and life-threatening if blood elements are involved via the immune or nonimmune mechanisms and if they result in hepatitis.
Кључне речи:
hypersensitivity syndrome / carbamazepine / leukopenia / hepatitis / skin rash / lymphadenopathyИзвор:
Allergologie, 2004, 27, 11, 468-472Издавач:
- Dustri-Verlag Dr Karl Feistle, Deisenhofen-Muenchen
DOI: 10.5414/ALP27468
ISSN: 0344-5062
WoS: 000225548200005
Scopus: 2-s2.0-10344233168
Институција/група
TorlakTY - JOUR AU - Bogić, Mirjana AU - Rašković, S. AU - Sojić, J. AU - Boricić, I. AU - Ješić, R. AU - Burazer, Lidija AU - Spirić, V.T. AU - Popadić, A.P. AU - Đurić, V. AU - Celeketić, D. PY - 2004 UR - http://intor.torlakinstitut.com/handle/123456789/174 AB - Drug hypersensitivity syndrome is a severe form of hypersensitivity to the antiepileptic agent carbamazepine, particularly in presence of visceral and hematological manifestations that must be evidenced and treated in time. Two cases of female patients with carbamazepine-induced hypersensitivity syndrome are reported. Both patients had prominent general complaints (febricity, weakness). The first patient had leukopenia, lymphadenopathy and rash, while the other one had urticaria, angioedema and hepatitis after administration of carbamazepine. Hypersensitivity reactions induced by antiepileptics widely applied in the practice may be severe and life-threatening if blood elements are involved via the immune or nonimmune mechanisms and if they result in hepatitis. PB - Dustri-Verlag Dr Karl Feistle, Deisenhofen-Muenchen T2 - Allergologie T1 - Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases EP - 472 IS - 11 SP - 468 VL - 27 DO - 10.5414/ALP27468 ER -
@article{ author = "Bogić, Mirjana and Rašković, S. and Sojić, J. and Boricić, I. and Ješić, R. and Burazer, Lidija and Spirić, V.T. and Popadić, A.P. and Đurić, V. and Celeketić, D.", year = "2004", abstract = "Drug hypersensitivity syndrome is a severe form of hypersensitivity to the antiepileptic agent carbamazepine, particularly in presence of visceral and hematological manifestations that must be evidenced and treated in time. Two cases of female patients with carbamazepine-induced hypersensitivity syndrome are reported. Both patients had prominent general complaints (febricity, weakness). The first patient had leukopenia, lymphadenopathy and rash, while the other one had urticaria, angioedema and hepatitis after administration of carbamazepine. Hypersensitivity reactions induced by antiepileptics widely applied in the practice may be severe and life-threatening if blood elements are involved via the immune or nonimmune mechanisms and if they result in hepatitis.", publisher = "Dustri-Verlag Dr Karl Feistle, Deisenhofen-Muenchen", journal = "Allergologie", title = "Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases", pages = "472-468", number = "11", volume = "27", doi = "10.5414/ALP27468" }
Bogić, M., Rašković, S., Sojić, J., Boricić, I., Ješić, R., Burazer, L., Spirić, V.T., Popadić, A.P., Đurić, V.,& Celeketić, D.. (2004). Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases. in Allergologie Dustri-Verlag Dr Karl Feistle, Deisenhofen-Muenchen., 27(11), 468-472. https://doi.org/10.5414/ALP27468
Bogić M, Rašković S, Sojić J, Boricić I, Ješić R, Burazer L, Spirić V, Popadić A, Đurić V, Celeketić D. Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases. in Allergologie. 2004;27(11):468-472. doi:10.5414/ALP27468 .
Bogić, Mirjana, Rašković, S., Sojić, J., Boricić, I., Ješić, R., Burazer, Lidija, Spirić, V.T., Popadić, A.P., Đurić, V., Celeketić, D., "Carbamazepine hypersensitivity syndrome with leukopenia and hepatitis - report of two cases" in Allergologie, 27, no. 11 (2004):468-472, https://doi.org/10.5414/ALP27468 . .