Ethanol consumption affecting some brain proteins and cortical plasticity might disturb the neural networks of long-term memory
Апстракт
The objective of this study is to investigate whether chronic ethanol consumption include brain damage expressed as; an increase of antibody titer to S-100 and synaptic membrane proteins, additioning of lateral ventricles volume and increasing within the brain cortex in the rats. After six months of ethanol consumption rats wer tested for antibody titer to S-100, neuron specific enolase (NSE), 14-3-2 and synaptic membrane proteins. In this rat's diameter of anterior, medial and posterior cortical areas and diameter of lateral ventricles were measured after histological examination. Ethanol consumption significantly increases antibody titer to V-100 and synaptic membranes, decrease antibody titer to 14-3-2 protein and do not affect antibody to NSE in peripheral blood of these animals. Additional volume of lateral right and left ventricles indicate that brain atrophy appears after six months of ethanol consumption. Increased diameter of anterior cortical area but not medial and posterior... cortical area indicate morphological changes in the brain cortical tissue in prefrontal, and frontal cortical areas that art, responsible for attention memory and associative long-term memory in this part of the brain. Of course, all of these morpho-functional changes in the cortex find some depth structures of the brain might disturb the function of neural networks for abovementioned types of memory in the brain.
Кључне речи:
ethanol / rats / NSA / S-100 / synaptic membranes / 14-3-2 protein / long-term memory / neural networksИзвор:
2004 Seventh Seminar on Neural Network Applications in Electrical Engineering - Proceedings, NEUREL, 2004, 165-170Издавач:
- IEEE, New York
Институција/група
TorlakTY - CONF AU - Jovanova-Nešić, Katica AU - Rakić, L. PY - 2004 UR - http://intor.torlakinstitut.com/handle/123456789/172 AB - The objective of this study is to investigate whether chronic ethanol consumption include brain damage expressed as; an increase of antibody titer to S-100 and synaptic membrane proteins, additioning of lateral ventricles volume and increasing within the brain cortex in the rats. After six months of ethanol consumption rats wer tested for antibody titer to S-100, neuron specific enolase (NSE), 14-3-2 and synaptic membrane proteins. In this rat's diameter of anterior, medial and posterior cortical areas and diameter of lateral ventricles were measured after histological examination. Ethanol consumption significantly increases antibody titer to V-100 and synaptic membranes, decrease antibody titer to 14-3-2 protein and do not affect antibody to NSE in peripheral blood of these animals. Additional volume of lateral right and left ventricles indicate that brain atrophy appears after six months of ethanol consumption. Increased diameter of anterior cortical area but not medial and posterior cortical area indicate morphological changes in the brain cortical tissue in prefrontal, and frontal cortical areas that art, responsible for attention memory and associative long-term memory in this part of the brain. Of course, all of these morpho-functional changes in the cortex find some depth structures of the brain might disturb the function of neural networks for abovementioned types of memory in the brain. PB - IEEE, New York C3 - 2004 Seventh Seminar on Neural Network Applications in Electrical Engineering - Proceedings, NEUREL T1 - Ethanol consumption affecting some brain proteins and cortical plasticity might disturb the neural networks of long-term memory EP - 170 SP - 165 UR - https://hdl.handle.net/21.15107/rcub_intor_172 ER -
@conference{ author = "Jovanova-Nešić, Katica and Rakić, L.", year = "2004", abstract = "The objective of this study is to investigate whether chronic ethanol consumption include brain damage expressed as; an increase of antibody titer to S-100 and synaptic membrane proteins, additioning of lateral ventricles volume and increasing within the brain cortex in the rats. After six months of ethanol consumption rats wer tested for antibody titer to S-100, neuron specific enolase (NSE), 14-3-2 and synaptic membrane proteins. In this rat's diameter of anterior, medial and posterior cortical areas and diameter of lateral ventricles were measured after histological examination. Ethanol consumption significantly increases antibody titer to V-100 and synaptic membranes, decrease antibody titer to 14-3-2 protein and do not affect antibody to NSE in peripheral blood of these animals. Additional volume of lateral right and left ventricles indicate that brain atrophy appears after six months of ethanol consumption. Increased diameter of anterior cortical area but not medial and posterior cortical area indicate morphological changes in the brain cortical tissue in prefrontal, and frontal cortical areas that art, responsible for attention memory and associative long-term memory in this part of the brain. Of course, all of these morpho-functional changes in the cortex find some depth structures of the brain might disturb the function of neural networks for abovementioned types of memory in the brain.", publisher = "IEEE, New York", journal = "2004 Seventh Seminar on Neural Network Applications in Electrical Engineering - Proceedings, NEUREL", title = "Ethanol consumption affecting some brain proteins and cortical plasticity might disturb the neural networks of long-term memory", pages = "170-165", url = "https://hdl.handle.net/21.15107/rcub_intor_172" }
Jovanova-Nešić, K.,& Rakić, L.. (2004). Ethanol consumption affecting some brain proteins and cortical plasticity might disturb the neural networks of long-term memory. in 2004 Seventh Seminar on Neural Network Applications in Electrical Engineering - Proceedings, NEUREL IEEE, New York., 165-170. https://hdl.handle.net/21.15107/rcub_intor_172
Jovanova-Nešić K, Rakić L. Ethanol consumption affecting some brain proteins and cortical plasticity might disturb the neural networks of long-term memory. in 2004 Seventh Seminar on Neural Network Applications in Electrical Engineering - Proceedings, NEUREL. 2004;:165-170. https://hdl.handle.net/21.15107/rcub_intor_172 .
Jovanova-Nešić, Katica, Rakić, L., "Ethanol consumption affecting some brain proteins and cortical plasticity might disturb the neural networks of long-term memory" in 2004 Seventh Seminar on Neural Network Applications in Electrical Engineering - Proceedings, NEUREL (2004):165-170, https://hdl.handle.net/21.15107/rcub_intor_172 .