Virus isolation from the kidney, tumors and lymph nodes of patients with ben

Abstract

This paper is based on two recent publications (1,2), and one submitted for publication (submittted for publi-cation). There is an important correction. In the two previous publications in Nephron it was stated that the virus isolated from the kidneys, the tumors and meta-static lymph glands was classified as a coronavirus (1,2). Subsequent more detailed investigations revealed that the virus should not be identified as a coronavirus (submittted for publication). However, the evidence presented in this work suggests strongly that the newly isolated virus is involved in the ethyology of BEN. The new findings open the possibility of reassessment of this still mysterious disease. A virus was isolated from kidneys, tumors and meta-static lymph glands from cases of BEN. The material was obtained at operations of tumors of the urinary tract. The identity of the virus has yet to be established. In cases of BEN with tumors, anti-bodies were found in all the patients. The identity of the virus is the sub-ject of a companion paper (Riquelme C, Escors D, Ortego J, Sanchez CM, Uzelac-Keserovic B Enjuanes L. sub-mitted for publication). The evidence presented sug-gests strongly that as yet an unidentified virus is in-volved in the aetiology of BEN. There are still many unresolved questions concerning the putative virus.