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Gonadal hormone dependent developmental plasticity of catecholamine:beta 2-adrenoceptor signaling complex in male rat thymus: Putative implications for thymopoiesis
(Elsevier, Amsterdam, 2013)
The study was undertaken considering that: i) androgens affect beta(2)-adrenoceptor (AR)-mediated catecholamine (CA) action in many tissues; and ii) peripubertal changes in both circulating androgen and thymic CA levels ...
Neonatal androgenization affects the efficiency of beta-adrenoceptor-mediated modulation of thymopoiesis
(Elsevier Science Bv, Amsterdam, 2011)
We tested the hypothesis that neonatal androgenization affects the efficacy of beta-adrenoceptor (beta-AR)-mediated fine tuning of thymopoiesis in adult female rats by modulating the thymic noradrenaline (NA) level and/or ...
Effects of catecholamines on thymocyte apoptosis and proliferation depend on thymocyte microenvironment
(Elsevier, Amsterdam, 2014)
The present study, through quantification of tyrosine hydroxylase (TH) expression and catecholamine (CA) content in the presence and in the absence of alpha-methyl-p-tyrosine (AMPT), a TH inhibitor, in adult thymic organ ...
Age-related changes in spleen of Dark Agouti rats immunized for experimental autoimmune encephalomyelitis
(Elsevier Science Bv, Amsterdam, 2015)
The study was undertaken considering age-related changes in susceptibility to experimental autoimmune encephalomyelitis (EAE) and a putative role of spleen in pathogenesis of this disease. The phenotypic and functional ...
NPY suppressed development of experimental autoimmune encephalomyelitis in Dark Agouti rats by disrupting costimulatory molecule interactions
(Elsevier, Amsterdam, 2012)
Neuropeptide Y (NPY) suppressed clinical experimental autoimmune encephalomyelitis (EAE) and reduced numbers of CD28+, CD11b+ and CD80+ cells among spinal cord infiltrating cells at the peak of disease in Dark Agouti rat ...
Peripubertal ovariectomy influences thymic adrenergic network plasticity in adult rats
(Elsevier Science Bv, Amsterdam, 2016)
The study investigated the influence of peripubertal ovariectomy on the thymic noradrenaline (NA) concentration, and the thymocyte NA content and beta(2)- and alpha(1)-adrenoceptor (AR) expression in adult 2- and 11-month-old ...